along the way…

Posted on Monday 10 October 2011

This is a rambler, following up on this morning’s question about paper churning.

Dr. John Rush is the master at it [whatever the point]. Rush’s CV as of January 2011 lists 638 articles. On PubMed he has 533 as of today. Whatever the actual count, it’s pretty impressive. Back when I was looking at STAR*D, I noticed that most of Rush’s STAR*D articles said "The authors acknowledge the editorial support of Jon Kilner, M.S., M.A." [a study in pollen…]. Jon Kilner’s not that hard to locate [http://kilnerwriter.net/]. He’s a trained medical writer as his day job, but he also writes other science fiction [Songs of Ice and Darkness].

Besides being a megaprolific article generator, Dr. Rush achieved notoriety in 2008 by making Senator Grassley’s list of luminaries, and promptly left Texas for Singapore [the singapore sojourn? ask Alice…] to take a position at Duke NUS [a Medical Graduate School in Singapore]. My interpretation of that move was that he needed to escape not just Grassley’s scrutiny, but also to get away from Texas where there’s a really big suit against Johnson & Johnson for mega-hanky-panky in the Texas Medical Algorithm Project [which Rush directed from its inception]:
 
About 12 minutes across Singapore from Duke, there’s a separate enterprise that does Clinical Trial consulting:
Dr. Rush is over at SCRI too. As best I can tell, it’s a Clinical Research Organization involved in multiple aspects of Clinical Research and, as it turns out, getting things published [moving to Singapore certainly only slowed down the steady output from Dr. Rush, with Jon Kilner’s editorial assistance]. Looking around on the SCRI site, I of course wanted to take a look at their Mission and Vision Statements [always a sure-fire way to understand a company – clear, direct, to the point]. It was a large graphic and on the bottom it concluded with their signature 5 ‘C’s:
 

I particularly honed in on Collaboration and Co-authorship, having marveled not only at the number of papers John Rush has authored, but the number of co-authors on most of them. Then I remembered something – a comment Nancy Wilson had made back in April. She had been at UT, and sent a link to a slide presentation by Dr. Rush from September 2006 that definitely fits this topic. Look it over. Dr. Rush is the go-to man for getting things published, and getting many papers out of a single study. It’s actually an amazing document and is right in line with SCRI’s 5 ‘C’s.

So why am I writing about this? I had entered Jon Kilner’s name in Google to relocate his web site when I wrote that last post. Most of what came up were references to things in the Science Fiction fanzine list-serves. Then I ran across this:

In Singapore, the prevalence of end-stage renal disease (ESRD) and the number of people on dialysis is increasing. The impact of ESRD on patient quality of life has been recognized as an important outcome measure. The Kidney Disease Quality Of Life-Short Form (KDQOL-SF™) has been validated and is widely used as a measure of quality of life in dialysis patients in many countries, but not in Singapore. We aimed to determine the reliability and validity of the KDQOL-SF™ for haemodialysis patients in Singapore.

Conclusions: The psychometric properties of the KDQOL-SF™ resulting from this first-time administration of the instrument support the validity and reliability of the KDQOL-SF™ as a measure of quality of life of haemodialysis patients in Singapore. It is, however, necessary to determine the test-retest reliability of the KDQOL-SF™ among the haemodialysis population of Singapore.

Huh? Then I looked at the bottom of the full text version of the paper:
Acknowledgements …The authors appreciate the support of the Singapore Clinical Research Institute for the editorial assistance provided by Jon Kilner, MS, MA (Pittsburgh, PA., USA).
I would suspect that Jon Kilner is a ghost writer, but there’s no way I can prove such a thing. It looks like whatever-he-does, he’s not just writing/editorial-assistantizing for Dr. Rush, but is marketing his whatever-he-does through Dr. Rush’s Singapore Clinical Research Institute.

There’s something fundamental about this story that I’m pretty sure I’m not capable of understanding. He and I trained at approximately the same time, both did some time in the military, and both stayed on the faculty after training. This has been the strangest of times in the world of psychiatry, but it’s impossible for me to follow how that lead to him to where he is today – an expert on churning out scientific papers, living in Singapore. There’s a court trial next month against a Pharmaceutical Company [Johnson & Johnson] that alleges that the Texas Medical Algorithm Project that Dr. Rush directed was a scam – a way of directing doctors in public medical facilities [ultimately in sixteen States] to use drugs that were extremely expensive, but no better than the available generic drugs. The only reason for the program that I can see was to line the drug companies’ pockets with money. And the bulk of Dr. Rush’s copious article output recently is about some studies that cost the NIMH a mint, but yielded next to nothing [STAR*D and CO-MED].

To me, this a sad story. Something went terribly wrong along the path…

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