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Archive for July, 2013

a shameful misuse…

Ghost- and Guest-Authored Pharmaceutical Industry-Sponsored Studies: Abuse of Academic Integrity, the Peer Review System, and Public Trust by Dennis K Flaherty, PhD Annals of Pharmacotherapy. 2013 47:1081-1083. [full text on-line] Industry-sponsored ghost- and guest-authored clinical research publications are a continuing problem in medical journals. These communications are written by unacknowledged medical communication companies and submitted […]

down the rabbit hole…

There is only so much mileage to be gained from discussing a 20+ year old legal case and the square-off between Drs. Klerman and Stone. For those of us living through those days, it can’t help but bring up the feelings from that time. And if you have access to the literature, the published articles […]

faded from the rolls…

In the transcript of Osherhoff v. Chestnut Lodge, there’s a confusion of tongues [to borrow a term]. The opening description talks about two kinds of depression, the longstanding prevailing view in psychiatry: There are two kinds of depression known to psychiatry. One kind of depression is an individual’s reaction to external situations and events. It […]

a loud creaking noise…

This is from a transcript of Osherhoff v. Chestnut Lodge in 1985, amended after a failed arbitration. I can’t find the original from 1982. I suspect that the wording of number 6. might have been changed between the two but that’s just a guess that I can’t confirm: III. SUMMARY OF THE CASE 4. Dr. […]

respecting our limits…

I often use the word cloistered to describe my twenty years between retiring and leaving an academic position [that I had thought would be my career] to go into practice. It wasn’t exactly a choice. There was a new psychiatry arriving like a tsunami – one now well known to us. And there was an […]

just endure…

for every roach you see, there are a hundred behind the wall… One thing about transparency, it’s irrelevant if you don’t look. So first, Propublica’s Dollars for Docs: Charles B. Nemeroff   Johnson & Johnson   2011   Meals   $111 Charles Barnet Nemeroff Allergan 2012 Combination $1-1,000 Charles Nemeroff Eli Lilly 2011 Meals $118 […]

no red flags…

I did regressions among the reported means from the Atypical meta-analysis [the mother of meta…] using only the Atypicals approved in the US starting with Risperidal in 1994. The only significant linear regressions I could find with an Open Office Spreadsheet were these two [my cabin didn’t come equipped with SAS]:   The only correlation […]

should’ve listened then…

Several have written in the comments or emailed me with some "did they?…" questions and comments about the article in the last post [the mother of meta…]. I have a lot of those questions myself, but I probably didn’t convey how mega this meta really is. Besides being a long and dense article itself, it […]

the mother of meta…

I said a few days ago that I never met a graph I didn’t like, but there’s been a graph that I’ve wanted to see for years, but I never found the data to draw it. But as of today, I can put all of that behind me: On the left, the Efficacy of the […]