When you read an article in a medical journal, all you have to go on is what you’re told in the article itself. If you watched Dr. Healy’s commentary [background music…], you know that this 11 page article represents 77,000 pages of data locked away in some data archive out of sight, a compression ratio […]
The RIAT Initiative was a bright idea. Rather than simply decrying unpublished or questionable Clinical Trials, it offers the original authors/sponsors the opportunity to set things right. If they decline, the RIAT Team will attempt to do it for them with a republication. Success depends on having access to the raw trial data and on […]
Efficacy of Paroxetine in the Treatment of Adolescent Major Depression: A Randomized, Controlled Trial by Keller MB, Ryan ND, Strober M, Klein RG, Kutcher SP, Birmaher B, Hagino OR, Koplewicz H, Carlson GA, Clarke GN, Emslie GJ, Feinberg D, Geller B, Kusumakar V, Papatheodorou G, Sack WH, Sweeney M, Wagner KD, Weller EB, Winters NC, […]
I sure don’t want to become 1·terminally·boring·old·man. On the other hand, this is my only available format for communicating. I want to write about the process of evaluating Trials anyway, but I also have a practical reason. A lot of us have clamored for access to the raw data from Clinical Trials, realizing that a […]
"Will this drug help me?" "… hurt me?" "… do nothing?" "What if I don’t take it?" Questions asked as if there’s an answer. But in every case the answer is in the form of likelihoods, not certainties. Each question has "how much?" tacked on – "how much might it help me?" "… hurt me?" […]
"There is only one difference between a bad economist and a good one: the bad economist confines himself to the visible effect; the good economist takes into account both the effect that can be seen and those effects that must be foreseen…" French Journalist/Economist Frédéric Bastiat The Law of Unintended Consequences is an all too […]
em·bar·go noun an official ban on trade or other commercial activity with a particular country. "an embargo on grain sales" verb impose an official ban on (trade or a country or commodity). "the country has been virtually embargoed by most of the noncommunist world" seize (a ship or goods) for state service. The video in […]
a little background music from David Healy… A Milestone in the Battle for Truth in Drug Safety August, 17, 2015 Study329.org: The Panorama Files August, 27, 2015 Study 329: The Timelines August, 31, 2015 Study329.org: Science with a Conscience September, 3, 2015 Original Study 329 Team September, 3, 2015
pen·ance noun: penance; plural noun: penances voluntary self-punishment inflicted as an outward expression of repentance for having done wrong. "he had done public penance for those hasty words" a Christian sacrament in which a member of the Church confesses sins to a priest and is given absolution. At the first of the month, I usually […]
In our recent project, I had to bone up on my statistics. It was actually pretty interesting in that the statistical tests themselves haven’t changed all that much since my hard science days. But it wasn’t like riding a bicycle exactly, more like going to a class reunion where there’s an awkward start, but with […]