I took a several week unpaid leave of absence from blogging and email commerce to do a number intense project. I found that I just couldn’t do it if I thought about anything else. I finished the part that had to be done yesterday, and look forward to returning to my normal mental life. Looking […]
I got an email asking if I was sick [because I’ve been quiet for a week]. No, I am just knee deep in a project that involves scrolling through endless monotonous spreadsheets, and I just can’t look at a computer after a few [or more] hours of that. Probably another week more I would guess. […]
Don’t be alarmed. This isn’t one of those long boring posts with formulas and numbers. The graphic below is just window dressing to make one simple point: I’ve been writing a mini-tutorial for evaluating Clinical Trials, and this spreadsheet will generate the needed information in the absence of Data Transparency. All we need for the […]
The Categorical Variables just get one post. It’s not because they aren’t important. It’s because I’ve already said what I’m up to in this series. And because they’re easy… METHOD 1: the spreadsheet I thought it would be easiest to start with the spreadsheet itself this time because the column headings make it easy to […]
Being born in early December 1941 meant that I came in at the end of the last movie just when the next one was starting. And by the time I came into awareness, there were a couple of realities that for all I knew had always been in place – the Iron Curtain and the […]
Robert Spitzer, 83, Dies; Psychiatrist Set Rigorous Standards for Diagnosis New York Times By Benedict Carey December 26, 2015 The Passing of Robert Spitzer Architect of the DSM Psychology Today By Edward Shorter December 28, 2015 Setting the Record Straight: The Psychiatric Legacy of Robert Spitzer Mad in America By Bonnie Burstow, PhD January 05, […]
In a way, what I’m trying to do here is at cross purposes with some of my own beliefs. Short term Randomized Clinical Trials [RCTs] can tell us whether a drug has the desired medicinal properties; something about the strength of those properties; the incidence of early adverse effects; and can identify some but certainly […]
Generally, folk heros are from the past like John Henry and represent some laudable principle – like man versus machine. Back in the upside-down years of the 60s, Arlo Guthrie had a shot with his endless comical antiwar song, Alice’s Restaurant. The premise, however, was dead serious. When enough people get behind a needed change, […]
I got a bit garbled at the end of the last post, so let me start over. I’ve been looking at these two studies, each of which have four groups – placebo and three doses of medication. My table shows three pairwise comparisons in two articles – placebo vs each dose of Brexpiprazole: The results […]