Archives

Archive for April, 2016

a must read…

( OPINION )

Amid Public Feuds, A Venerated Medical Journal Finds Itself Under Attack ProPublica/Boston Globe by Charles Ornstein April 5, 2016 The New England Journal of Medicine is arguably the best-known and most venerated medical journal in the world. Studies featured in its pages are cited more often, on average, than those of any of its peers. […]

a sacred clown…

( OPINION )

“Evidence-based medicine has been hijacked:” A confession from John Ioannidis Retraction Watch by Ivan Oransky March 16th, 2016 John Ioannidis is perhaps best known for a 2005 paper “Why Most Published Research Findings Are False” … Earlier this month, he published a heartfelt and provocative essay in the the Journal of Clinical Epidemiology titled “Evidence-Based Medicine […]

a couple of points…

( OPINION )

The residue of undue influence we call Conflict of Interest spreads like jungle vines in an deserted temple, and the longer the absence, the harder the restoration. In a recent [silly] JAMA Viewpoint article, Confluence, Not Conflict of Interest Name Change Necessary JAMA by Anne R. Cappola and Garret A. September 24, 2015 we were […]

a pipeline rejig…

( OPINION )

In the course of reading about the FDA’s rejection of Lundbeck/Takeda‘s bid for a Cognitive Dysfunction in MDD for Brintellix® [still going strong?…], I ran across another article in FiercePharma, the one that got me thinking about the pipeline in general [the pipeline paradigm…]. It’s about another Lundbeck drug – an Atypical Antipsychotic [Lu AF35700] […]