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Archive for May, 2011

on another topic…

This afternoon, my wife had gone to the store and I flipped on the television. I think I was looking for the weather this weekend for an event, but it was on a news channel, and they were talking about the pear tree that survived 911 and has been replanted at Ground Zero. I think […]

Godzilla vs. Ghidorah [the Three Headed Monster from Outer Space]

  circa 1964 Okay, so my Japanese filmography is a little off. The first Godzilla versus movie pitted Godzilla against King Kong [right]. I just couldn’t resist the Godzilla vs. Ghidorah the Three Headed Monster from Outer Space visual to describe the coming face off over the fate of personalized medicine in psychiatry between Evian […]

the race for biomarkers…

Dual medications for depression increases costs, side effects with no benefit to patients UT Southwestern Medical Center May 2, 2011 Taking two medications for depression does not hasten recovery from the condition that affects 19 million Americans each year, researchers at UT Southwestern Medical Center have found in a national study.“Clinicians should not rush to […]

the inertia of ink…

You know, once you get into these drug industry matters, it just keeps on coming. Pharmalot, Soulful Sepulcher, Is Something Not Quite Right With Stan [hat tip to stan] are all over a recent article in PLoS Medicine about Abilify as a maintenance Bipolar therapy: Aripiprazole in the Maintenance Treatment of Bipolar Disorder: A Critical […]

the list…

I don’t know Dr. Maurizio Fava or anything about him other than he’s at Mass General and his name in embeded in the author lists of STAR*D. So I’m using him as a straw man simply because of his conflict of interest declaration on the recent CO-MED publication. In the ProPublica Dollars for Docs Database, […]

either way…

from the NIMH Grant Description: The results of the STAR*D trial prompted the next follow-on effectiveness trial study for the treatment of MDD, "Combining Medications to Enhance Depression Outcomes [CO-MED]." The CO-MED trial, supported by this contract modification, addresses the following specific questions regarding the use of combination medication therapy: Do patients who receive combination […]

the $tealthy $eduction $ummit…

Identifying KOLs and their Expertise to Increase Product Education and Awareness Bridging KOL Relationships within a Company to Enhance Team Dynamics Identifying the Changing Landscape of KOLs while Continuing to Improve the Sponsoring Company’s Overall Reputation Providing Insight, Suggestions, and Strategies to further Engage and Collaborate with KOLs Using Digital Tools and Online Communities What […]

another “dud”…

CO-MED was published on-line yesterday [see co-med?…, re: CO-MED…]. It was a study  where depressed subjects were tried on monotherapy versus two-drugs therapy. There was no Placebo group. The three groups in the study were: Escitalopram [Lexapro] Plus Placebo (N=224) Sustained-Release Bupropion [Wellbutrin SR] Plus Escitalopram [Lexapro] (N=221) Extended-Release Venlafaxine [Effexor XR] Plus Mirtazapine [Remeron] […]

tora bora belated…

I wish I could feel joy about Bin Laden’s demise. I would have felt that in December 2001… TORA BORA REVISITED: HOW WE FAILED TO GET BIN LADEN AND WHY IT MATTERS TODAY COMMITTEE ON FOREIGN RELATIONS UNITED STATES SENATE By John F. Kerry NOVEMBER 30, 2009 Removing the Al Qaeda leader from the battlefield […]

the vacuum…

So I’m in Raleigh to hear my daughter sing Elijah with the Raleigh Chorus [she’s got the solos] and we meet for coffee this morning. She’s a Clinical Psychologist and she’s talking about an anorexia client of hers she’s mentioned before [a ‘young’ 19 year old]. My daughter says, "She stopped her Prozac and her […]