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Archive for April, 2012

not there…

DSM-5 Status of Psychotic Disorders: 1 Year Prepublication EDITORIAL by Rajiv Tandon and William T. Carpenter, Jr. Schizophrenia Bulletin. 2012 38[3]:369–370. EPub April 13, 2012 The Psychosis Work Group, of which the authors are members, will complete work in 2012. Final recommendations must be reviewed and approved in order for full text to go to […]

pay the price…

J&J’s Gorsky Should Be Forced to Testify in Suit, U.S. Says Reuters By Margaret Cronin Fisk Apr 13, 2012 Johnson & Johnson’s recently named Chief Executive Officer Alex Gorsky should be ordered to give sworn testimony in a lawsuit claiming the company paid kickbacks to influence sales of the antipsychotic drug Risperdal to nursing home […]

someday soon…

DSM-5 Track at the 2012 APA Annual Meeting Philadelphia, PA; May 5-9, 2012 DSM-5: Research and Development Saturday, May 5, at 9-10:30 a.m. Chair: David Kupfer, M.D.; Co-Chair: Darrel A. Regier, M.D., M.P.H Presenters: Darrel A. Regier, M.D., M.P.H. Lawson Wulsin, M.D. David Goldberg, M.D. William E. Narrow, M.D., M.P.H. Field Trial Testing of Proposed […]

an anatomy of a deceit 6…
    anticipated and forestalled

What makes these recent articles of Dr. Gibbons so remarkable is that the issue being debated has been covered so many times before with the same, monotonous arguments. Since the beginning of the Prozac Era, clinicians have seen and reported cases where the Selective Serotonin Reuptake Inhibitors can, on occasion, have a paradoxical effect causing […]

an anatomy of a deceit 5…
    the purloined letter

Nihil sapientiae odiosius acumine nimio Nothing is more hateful to wisdom than excessive cleverness This epigraph to The Purloined Letter attributed by Poe to Seneca was not found in Seneca’s known work. It is from Petrarch’s treatise "De Remediis utriusque Fortunae". [ref] I thought I had my ducks in a row, so I submitted my […]

an anatomy of a deceit 4…
    the letter

SUBMITTED FOR PUBLICATION to the Archives of General Psychiatry April 6, 2012 390 words, two tables, 9 references Safety and Efficacy of Antidepressant Medication in Youths Dear Sir, This meta-analysis [1][2] is deeply flawed by inappropriate data selection and computational irregularities invalidating the interpretation of their conclusions. By using only adult venlafaxine trials, they eliminated […]

an anatomy of a deceit 3…
    readin’ and writin’ and ‘rithmetic

Almost everyone knows what a p value is – how probable is it that a difference is real and not just a sampling error? And we know p < 0.05 is good enough; p < 0.01 is real good; and p < 0.001 is great. In this case, the outcome variable was the CDRS-R [Child […]

an anatomy of a deceit 2…
    the fog comes on little cat feet

Benefits From Antidepressants: Synthesis of 6-Week Patient-Level Outcomes From Double-blind Placebo-Controlled Randomized Trials of Fluoxetine and Venlafaxine by Robert D. Gibbons, PhD; Kwan Hur, PhD; C. Hendricks Brown, PhD; John M. Davis, MD; and J. John Mann, MD Archives of General Psychiatry. Published online March 5, 2012. … Conclusions: To our knowledge, this is the […]

an anatomy of a deceit 1…
    introduction

I’ve borrowed my title from Marcie Wheeler’s book [Anatomy of Deceit]. She wrote a detailed narrative of the Bush Administration’s lying us into the Invasion of Iraq and the cover-up that followed, specifically involving Joseph Wilson and his wife, Valerie Plame – the outed CIA Agent. Marcie Wheeler is a Comparative Literature Ph.D. who wrote […]

an old n=1 type…

Here are the references for the two groups studying the "ultra high risk" patients… Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms. by McGorry PD, Yung AR, Phillips LJ, Yuen HP, Francey S, Cosgrave EM, Germano D, Bravin J, McDonald T, […]