the silent treatment…

Posted on Tuesday 11 September 2012

I’m running out of titles – all quiet on the western front, the sounds of silence, the silent treatment – ways to describe the status of the DSM-5 Revision. There’s suddenly nothing to say. The full report on the field trials has yet to appear. The PR site, DSM-5 Facts, won’t even come up right now, but on my last fly-by, it looked the same as it looked in May. Google news finds neither David Kupfer nor Darrel Regier in anything recent. My understanding is that the DSM-5 Task Force is to present the final product to the APA Board of Trustees in November, a month or so hence. Dr. Allen Frances has gone quiet. Suzy Chapman’s blog, dxrevisionwatch.com, the usual resource for matters DSM-5 is likewise quiet. She did report that HHS announced a delay until October 2014 for the implementation of the ICD-10-CM –


[click the graphic for the original]

– and wondered if the HHS decision might spark a delay with the DSM-5, but it didn’t. Apparently the DSM-5 is on schedule. As for the DSM-5 site, if it has been updated recently, I can’t find where. During these several months of silence, I’ve thought about the DSM-5 off and on. Silence would be a good space for pondering, but there’s nothing much to ponder.

From my vantage as someone watching from the outside, it seems like the DSM-5 effort was begun at the crest of a movement, setting out to extend the biological paradigm to new heights with A Research Agenda for DSM-5:
    In the ongoing quest to improve our psychiatric diagnostic system, we are now searching for new approaches to understanding the etiological and pathophysiological mechanisms that can improve the validity of our diagnoses and the consequent power of our preventive and treatment interventions venturing beyond the current DSM paradigm and DSM-IV framework. This thought-provoking volume produced as a partnership between the American Psychiatric Association, the National Institute of Mental Health, the National Institute on Alcohol Abuse and Alcoholism, and the National Institute on Drug Abuse represents a far-reaching attempt to stimulate research and discussion in the field in preparation for the eventual start of the DSM-V process, still several years hence. The book:

    • Explores a variety of basic nomenclature issues, including the desirability of rating the quality and quantity of information available to support the different disorders in the DSM in order to indicate the disparity of empirical support across the diagnostic system.
    • Offers a neuroscience research agenda to guide development of a pathophysiologically based classification for DSM-V, which reviews genetic, brain imaging, postmortem, and animal model research and includes strategic insights for a new research agenda.
    • Presents highlights of recent progress in developmental neuroscience, genetics, psychology, psychopathology, and epidemiology, using a bioecological perspective to focus on the first two decades of life, when rapid changes in behavior, emotion and cognition occur…
It’s important to note that this was a dramatic change. This was not the atheoretical descriptive DSM-III, this was to be the neuroscience based DSM-5 – something quite different from before. It was the dream of Robins and Guze coming to life at last. And for four years they had a series of conferences with experts discussing the clinical neuroscientific aspects of psychiatric conditions. During that four years, they failed to notice two things – what happened and what didn’t happen.

What happened? Academic Psychiatry and the Pharmaceutical Industry were increasingly implicated in a series of scandals culminating in a Senate investigation of prominent academic psychiatrists for payola and suits against the companies for fraud. "Psychiatric Expertise" was under suspicion. What didn’t happen? The anticipated neuroscience breakthroughs failed to materialize – the best that came from research was still promising or less. And the large NIMH drugs trials were hardly inspiring. The lofty goals from A Research Agenda for DSM-5 didn’t materialize. Had they noticed along the way, they could’ve changed gears and taken on improving the DSM-IV [their task in the first place]. But that’s not what they did. They added a bunch of idiosyncratic things and didn’t do much to fix the DSM-IV’s problems. When they began to talk publicly about where they were headed, their predecessors were aghast  and sounded alarms. Even then, they could’ve still turned things around. But that’s not what they did.

So it became too late. Their research agenda went nowhere – a failed enterprise. The delegated task of actually revising the DSM-IV stayed on the back burner too long and didn’t get done – so much for the other half which became an equally failed endeavor. The one-shot Field Trials were embarrassing. Throw in some arrogance in a time for humility and those peculiar diagnoses, and you have a perfect storm. The DSM-5 revision has allowed itself to become associated with the general disappointment in an oversold psychopharmacology, a lack of palpable progress in neuroscience, and the waves of scandal involving the the relationship between commercial enterprises and academic psychiatry.

 

There really isn’t much left to ponder in their silence…
  1.  
    jamzo
    September 12, 2012 | 12:55 PM
     

    FYI

    Millions Of Asthmatics May Fare Well Skipping Daily Steroids, Study Finds

    In a study that may overturn long-held guidelines for mild persistent asthma sufferers, researchers have found that people who inhale asthma medicine only when they have symptoms fare just as well as those who take daily inhaled steroid

    “The goal of our study was to compare different approaches to adjusting inhaled corticosteroid treatment on the frequency and severity of asthma attacks and on quality of life,’’ Boushey said. “This is not a treatment breakthrough but it may possibly open the door to a new approach to treatment, and it will certainly be considered by the expert panel for the NIH’s guidelines for asthma treatment.

    “This approach allows personalization of treatment and is easy for patients. Also, it could hypothetically result in saving $2 billion a year in medication costs,’’ Boushey said.

    UCSF co-authors are John V. Fahy, MD, a professor of pulmonary medicine, and Stephen C. Lazarus, MD, a professor of clinical medicine. The lead authors are William J. Calhoun, MD, and Bill T. Ameredes, PhD, of the University of Texas Medical Branch.

    “This is a step forward in asthma management,’’ Calhoun said. “It enables patients to use their steroids only when they have symptoms. It is ‘temporal personalization,’ adjusting medication on a day to day basis.’’

    http://commonhealth.wbur.org/2012/09/asthmatics-skip-daily-steroids

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