"I’m a kind of paranoiac in reverse. I suspect people of plotting to make me happy." Raise High the Roof Beam, Carpenters [1955], J. D. Salinger The last five years of writing about the misadventures of the pharmaceutical industry and the contingency of cooperating KOLs in academic psychiatry and elsewhere have taken something away from […]
It has appeared to me that the die was cast for the DSM-5 long before the revision process proper was ever underway. I’ve repeatedly mentioned the book A Research Agenda for DSM-V – the 2002 book that set the stage for two major conceptual changes: the inclusion of biological parameters and the addition of dimensional […]
Depression Screening and Patient Outcomes in Pregnancy or Postpartum: A Systematic Review by Brett D. Thombsa, Erin Arthursi, Stephanie Coronado-Montoya, Michelle Rosemana, Vanessa C. Delisle, Allison Leavensa, Brooke Levis, Laurent Azoulay, Cheri Smith, Luisa Ciofanik, James C. Coyne, Nancy Feeley, Simon Gilbodym, Joy Schinazin, Donna E. Stewart,and Phyllis Zelkowitz Journal of Psychosomatic Research, online 28 […]
Scientific Pride and Prejudice New York Times By MICHAEL SUK-YOUNG CHWE January 31, 2014 SCIENCE is in crisis, just when we need it most. Two years ago, C. Glenn Begley and Lee M. Ellis reported in Nature that they were able to replicate only six out of 53 “landmark” cancer studies. Scientists now worry that […]
Give the Data to the People New York Times By HARLAN M. KRUMHOLZ FEB. 2, 2014 LAST week, Johnson & Johnson announced that it was making all of its clinical trial data available to scientists around the world. It has hired my group, Yale University Open Data Access Project, or YODA, to fully oversee the […]
Probably the reason that you don’t know about TORDIA [Treatment Of Resistant Depression In Adolescents] is that it was a doomed ship – cursed by fatal design and haunted by a storm of fate. By now you know that the new century of psychopharmacology opened with an all out assault on a new mental illness […]
Karen Wagner on Treating Kids With Antidepressants Fiddamans blog by Bob Fiddaman January 31, 2014 [full text on-line] You’d have to be from the planet Zog if you didn’t know who Karen Wagner was. Her name is synonymous with antidepressant pediatric studies. She added her name to the Paxil 329 ghostwritten paper without actually looking […]
Prenatal Depression in Women Hospitalized for Obstetric Risk by Anna R. Brandon, Madhukar H. Trivedi, Linda S. Hynan, Paula D. Miltenberger, Dana Broussard Labat, Jamie B. Rifkin, and C. Allen Stringer Journal of Clinical Psychiatry. 2008 69[4]: 635–643. [full text on-line] Objective: Little is known about depression during pregnancy in women with high maternal or […]