Shorty Rogers Quintet
Bud Shank Quartet
Usually, when we think of circuits, we think about a roughly circular path that ends in the same place it started, then repeats – like an electrical circuit or Escher’s fantastic circuit. But when people are talking about neural circuits, they seem to be using the term more like it’s used in the phrase, circuit […]
The Randomized Clinical Trial of a psychoactive drug follows a monotonous and simple course: a Protocol defines how the study is to be conducted and analyzed the protocol is submitted to the Institutional Review Board [IRB] on approval of the protocol, the trial is Registered on clinicaltrials.gov the Trial is conducted, double blinded the Results […]
The citalopram CIT-MD-18 pediatric depression trial: Deconstruction of medical ghostwriting, data mischaracterisation and academic malfeasance by Jureidini, Jon, Amsterdam, Jay, McHenry, Leemon International Journal of Risk & Safety in Medicine. 2016 28[1]:33-43. OBJECTIVE:Deconstruction of a ghostwritten report of a randomized, double-blind, placebo-controlled efficacy and safety trial of citalopram in depressed children and adolescents conducted in […]
It may seem peculiar, but it makes sense to me. As a young guy in medicine, I was pulled in two directions – research into things we don’t yet know, and the application of things we do know. The former was where my mind naturally headed, but the latter was what gave me a sense […]
Five years ago, I ran across an Australian company called Brain Resources. It appeared to be primarily a Brain Training enterprise, but they were into a lot of other things too. They were financing iSPOT, a clinical trial of personalized medicine trying to predict antidepressant drug choice based on Genetic and/or other testing. And they […]
All this talk of the recent suicide statistics and what they might mean isn’t my native land. I’m more used to thinking about suicide and meaning[s] one case at a time. I recalled something from my earliest days as a resident. One of the first lectures we had was about the standard suicide statistics. You […]
Dr. Insel’s selection as Director of the NIMH in 2002 was a surprise choice. After losing his position in the NIMH Intramural program, he came to Atlanta to head the Yerkes Primate Center. After one term, he was not reappointed [the scuttle-but – too controlling] and then became Director of a Translational Center, a research […]
All Aboard! As the ripples from the recently released suicide figures spread across the water, the usual suspects are being lined up to take the blame: not enough antidepressants, too many antidepressants, biomedical psychiatry, the American Psychiatric Association, the FDA’s Black Box Warning, Tom Insel’s NIMH, Managed Care, the Pharmaceutical Industry, Hospital Corporations, things like […]