As I tried to say in proxies…, while I can find plenty to criticize about the Clinical Research industry, I’ve realized that the problems come after the blind is broken, not before – that thing called publication bias. I mentioned two studies along the way by the same group about publication bias in psychiatric studies. Here […]
In September, I noticed yet another John Mann/Robert Gibbons article in a major journal proposing that an FDA Warning be ignored [Varenicline, Smoking Cessation, and Neuropsychiatric Adverse Events] [very monotonous…]. I wrote then: When you happen onto a really long blog post with lots of quotes, you can usually count on the fact that the […]
I try not to be boring and tedious, but sometimes it just can’t be helped. This post isn’t yet another commentary on Paxil Study 329, but it’s in the mix. It’s a timeline about all the studies SKB and GSK did on Paxil in adolescents. I think it’s of interest, but it may put others […]
UPDATE 10:41 PM: [beginning at 1:37] “Well what we’ve done – well sequentially we’ve been increasing the level of data transparency around the data we generate on clinical trials. So we’ve been publishing clinical trials summaries for a while. We’ve now committed the publish all of our clinical trial reports that are detailed reports of […]
reckon this is real?
I must’ve been pretty angry when I wrote that last post because my computer went belly-up in the process. Back in a while when the new one appears…
This is a reposting from August [a little light reading…]. Today, Ed Silverman of Pharmalot has an interview with Marc Rodwin, the Safra Fellow who put this collection together [see Pharma Corruption Hurts Patient Care & Medical Knowledge: Rodwin Explains]. It’s a good interview and a heady collection, but well worth the investment… Institutional Corruption […]
So last week I had my best ever idea yet [they already don’t…], and Nick took pity on that post [thanks Nick] because it looked lonely with no comments. Undeterred, I’m having another shot at it. The gist of things is that I think we’re trying to intervene at the wrong level. Clinical Trials are […]
I swore off political blogging after the 2008 election. I had avoided political commentary even at cocktail parties from the end of the Viet Nam War until the invasion of Iraq. I have no desire to go back to that. But this morning when I read this, I thought it had something to say about […]
In case you haven’t noticed, European [and World] psychiatry is pulling away from American psychiatry at a fairly brisk pace. Reform of the alliance between the pharmaceutical giants and medicine is centered in Europe [the EMA, the British Journal of Medicine, AllTrials, etc]. Articles critical of the DSM-5 are common in the European journals, but […]