I really have a distaste for grant applications. I did some when I was an NIH Fellow in the bronze age and much later wrote periodic training grants. I get it why one has to fill out all that stuff and look endlessly at the endless guidelines, but getting it doesn’t erase the tedium of […]
Drug regulator destroys Prozac research The Sunday Times by George Arbuthnott and Jonathan Leake 23 March 2014 No, I didn’t make the print disappear. It faded behind a right pricey Sunday Times paywall. If there’s anything to the story, the whole thing ought to show up on the Internet sooner or later. And I’m curious […]
Psycritic wrote a post in response to my on the wrong side of the equation… where I was making an analogy between dress designers having to constantly generate new products to keep the game going and some of our psychiatric KOLs who seem lost without something new from the psychopharmacologic pipeline. He had another take […]
[click for source] hat tip to jamzo… I don’t really know anything about patents and drug exclusivity in the UK. I presume it’s somewhat similar to the US [on the left][if that’s wrong, someone let me know]. The upper graph is number of prescriptions and the bottom graph is overall cost. I thought it was […]
In the summer of 2003, Dan Markingson became intensely psychotic with apocalyptic delusions and the belief that he would be called to become a murderer. After threatening to kill his mother, he was involuntarily hospitalized in the Fall and started on antipsychotic medication [Risperdal]. After several days, he was involuntarily committed to the mental hospital […]
A couple of months ago, when I first heard the testimony of AbbVie’s lawyer Neal Parker at the Brussels Conference on Data Transparency by the European Medicines Agency, I was horrified – an emotion I don’t often feel [a deal-breaker?…]. He’s a fast talker and is obviously emotionally engaged in his topic, and I couldn’t follow […]
No, I’m not going to try to spin the Battle of Gettysburg back in 1863 into something about the pharmaceutical industry and medicine. But I am going to talk about it anyway: I grew up in the South in a place where Civil War Cannons and Monuments were as common as bus stops. As a […]
Several weeks ago in no country for old men…, I mentioned a study that found some new SNPs associated with Schizophrenia [Genome-wide association analysis identifies 13 new risk loci for schizophrenia] that estimated that 8,300 SNPs would be involved accounting for 32% of the liability for the disorder [how these numbers were derived is beyond […]
Remember the DSM-5 Task Force? The Field Trials? The debates about what to call Dr. Biederman’s Bipolar youth once we got over them being Bipolar? The solution was Disruptive Mood Dysregulation Disorder [DMDD]. This time last year, we got to see the DSM-5 Field Trials, and DMDD didn’t fare very well, as it turned out […]
Pharmaceutical firms paid to attend meetings of panel that advises FDA Washington Post By Peter Whoriskey October 6, 2013 A scientific panel that shaped the federal government’s policy for testing the safety and effectiveness of painkillers was funded by major pharmaceutical companies that paid hundreds of thousands of dollars for the chance to affect the […]