{"id":10825,"date":"2011-07-01T10:12:10","date_gmt":"2011-07-01T14:12:10","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=10825"},"modified":"2011-07-01T16:52:07","modified_gmt":"2011-07-01T20:52:07","slug":"bipolar-kids-my-take-from-coby","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2011\/07\/01\/bipolar-kids-my-take-from-coby\/","title":{"rendered":"bipolar kids: my take from COBY&#8230;"},"content":{"rendered":"\n<div align=\"justify\">The <strong><font color=\"#990000\">DSM-III<\/font><\/strong> [1980] fractionated what had been called Manic Depressive Illness into two disorders &#8211; Major Depression, Recurrent and Bipolar Disorder[s] &#8211; based on the presence of a Manic Episode. It had a category &#8211; Atypical Bipolar Dsorder &#8211; for cases that did not meet their full criteria for Mania. In the <strong><font color=\"#990000\">DSM-IIIR<\/font><\/strong> [1988], they added that group as Bipolar Disorder NOS [and mentioned that it was being called &quot;Bipolar II&quot;]. By the coming of the <strong><font color=\"#990000\">DSM-IV<\/font><\/strong> [1994], that group had become Bipolar II. Now, in the <strong><font color=\"#200020\">COBY<\/font><\/strong> Study, Bipolar NOS is defined as another member of the family:<\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>Children  and adolescents aged 7 to 17 years 11 months (mean&plusmn;SD  age, 13.0&plusmn;3.1  years) whose primary diagnoses were DSM-IV BP-I or BP-II  or an  operationalized definition of BP-NOS were enrolled in the COBY  study.  Because the DSM-IV definition of BP-NOS is vague, BP-NOS was  defined as  the presence of clinically relevant BP symptoms that did not  fulfill the  DSM-IV criteria for BP-I or BP-II. In addition, subjects  were required  to have a minimum of elated mood plus 2 associated DSM-IV  symptoms or  irritable mood plus 3 DSM-IV associated symptoms, along  with a change in  the level of functioning, duration of a minimum of 4  hours within a  24-hour period, and at least 4 cumulative lifetime days  meeting the  criteria.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">And notice that the <em><strong><font color=\"#200020\">Polarity of the Index Episode<\/font><\/strong><\/em> in those cases is also <em><strong>Not otherwise specified<\/strong><\/em>:  <\/div>\n<div align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"453\" vspace=\"5\" height=\"115\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/bp-6.gif\" \/><\/div>\n<div align=\"justify\">Furthermore, in their new Bipolar NOS, between 30 and 40% of the cases don&#8217;t even have a periodic illness:  <\/div>\n<div align=\"center\"><img decoding=\"async\" width=\"400\" vspace=\"5\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/bp-2.gif\" \/><\/div>\n<div align=\"center\"><img decoding=\"async\" width=\"400\" vspace=\"5\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/bp-5.gif\" \/><\/div>\n<div align=\"justify\">So if&nbsp; <strong><font color=\"#400040\">Bipolar II<\/font><\/strong> is <strong><font color=\"#400040\">Bipolar Lite<\/font><\/strong>, then I guess that their version of <strong><font color=\"#400040\">Bipolar NOS<\/font><\/strong> is <strong><font color=\"#400040\">Bipolar UltraLite<\/font><\/strong>. I&#8217;m being facetious because I feel like I&#8217;m being played in this Study. It hides too much. I&#8217;d like to see a symptom breakdown, for example. The DSM isn&#8217;t solid enough to accept without some proof. Evidence-based medicine calls for evidence. And their&nbsp; comments about &quot;subsyndromal&quot; symptoms or:<\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>&#8230; a minimum of elated mood plus 2 associated DSM-IV  symptoms or   irritable mood plus 3 DSM-IV associated symptoms, along  with a change  in  the level of functioning, duration of a minimum of 4  hours within a   24-hour period, and at least 4 cumulative lifetime days  meeting the   criteria.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">feels contrived. So, I think they&#8217;re stretching the diagnosis of Bipolar Disorder to fit their preconceived notions. I admit to being a &quot;preconceived&quot; skeptic myself. For thirty years, I&#8217;ve been looking for the promised cohort of mis-diagnosed Bipolar adults, and they haven&#8217;t materialized. And since I&#8217;ve been working in the general clinics after my retirement, I&#8217;ve had to learn not to wince when people say, &quot;I&#8217;ve been diagnosed Bipolar&quot; or &quot;Do you think I might be Bipolar?&quot; There are some, sure enough, but the majority are people with longstanding characterologic problems of various sorts who take Bipolar medicines [which have not altered the course of their lives, by their own admission]. So I&#8217;m staying Kraepelinian, at least with adults.<\/div>\n<p align=\"justify\">On the other hand, I accept that the <strong><font color=\"#200020\">COBY<\/font><\/strong> Study has a respectable number of <strong><font color=\"#400040\">Bipolar I<\/font><\/strong> kids that seem to have all the right stuff for the diagnosis &#8211; duration of episode, appropriate periodicity, syndrome specific symptoms, family history. So, my take from this study is that I&#8217;m not a bipolar-kids-deny-er, just someone who thinks they&#8217;re pushing the diagnosis way further than they ought to. It makes perfect sense that the disorder would start in childhood, but I&#8217;d still like to see cases from childhood that went on to develop &quot;classic&quot; Manic Depressive adulthoods [and I&#8217;d still like to see a case in <em>the flesh<\/em>!].  <\/p>\n<div align=\"justify\">I&#8217;m particularly interested in the child and adolescent diagnostic category because I see them now [there&#8217;s not anyone else to see them here in the woods]. I may not know all I need to know to see them, but I&#8217;m way ahead of the alternatives. And I see lots of kids on Atypicals or some kind of Mood Stabilizers for questionable reasons, even by <strong><font color=\"#200020\">COBY <\/font><\/strong>standards. So I have first-hand knowledge that kids are being over-medicated or badly medicated. I have yet to see a child that fits these criteria, but I&#8217;ll keep looking. There are a couple of adolescents I&#8217;d give a <em>maybe<\/em> &#8211; usually with a <em>very<\/em> Bipolar parent. <\/div>\n","protected":false},"excerpt":{"rendered":"<p>The DSM-III [1980] fractionated what had been called Manic Depressive Illness into two disorders &#8211; Major Depression, Recurrent and Bipolar Disorder[s] &#8211; based on the presence of a Manic Episode. It had a category &#8211; Atypical Bipolar Dsorder &#8211; for cases that did not meet their full criteria for Mania. In the DSM-IIIR [1988], they [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-10825","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/10825","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=10825"}],"version-history":[{"count":24,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/10825\/revisions"}],"predecessor-version":[{"id":10849,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/10825\/revisions\/10849"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=10825"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=10825"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=10825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}