{"id":15237,"date":"2011-10-23T14:30:33","date_gmt":"2011-10-23T18:30:33","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=15237"},"modified":"2011-10-24T10:31:57","modified_gmt":"2011-10-24T14:31:57","slug":"2002","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2011\/10\/23\/2002\/","title":{"rendered":"2002&#8230;"},"content":{"rendered":"\n<p align=\"center\"><iframe loading=\"lazy\" width=\"420\" height=\"315\" src=\"http:\/\/www.youtube.com\/embed\/6RNdXMNJICg?rel=0\" frameborder=\"1\"><\/iframe><br \/> <sup>Paxil ad from 2001<\/sup><\/p>\n<p align=\"center\"><iframe loading=\"lazy\" width=\"420\" height=\"315\" src=\"http:\/\/www.youtube.com\/embed\/WY1HSCumuYY?rel=0\" frameborder=\"1\"><\/iframe><br \/> <sup>Paxil ad from 2002<\/sup><\/p>\n<p align=\"justify\">I just received a copy of a GSK Press Release from 2002, obviously published in response to the ruling in the last post. It speaks to a lot of things, but the central point is how corrupt things had become by then. They still had four years of patent protection ahead of them, and they were determined to milk it for all it was worth. Notice the language highlighted below, also the Key Opinion Leaders available for comment:            <\/p>\n<table width=\"80%\" cellspacing=\"0\" cellpadding=\"5\" border=\"0\" align=\"center\">\n<tr>\n<td>\n<div align=\"justify\"><strong><font color=\"#200020\">Philadelphia, PA, August 20, 2002<\/font><\/strong><\/div>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"justify\">GlaxoSmithKline (NYSE:              GSK) today announced it will appeal a ruling by a U.S. District              Court judge in Los Angeles requiring the company to alter its              television advertising for the anti-depressant Paxil&reg; (paroxetine              hydrochloride) that states that <em>Paxil<\/em> is <strong><font color=\"#200020\">not habit forming<\/font><\/strong>.                        <\/div>\n<p align=\"justify\">&quot;We are very disappointed in the ruling. The US Food and Drug              Administration (FDA) &#8211; and not the courts &#8211; has the expertise and              responsibility for reviewing and regulating pharmaceutical ads,&quot;              said David Stout, president of U.S. Pharmaceuticals at              GlaxoSmithKline. &quot;The <em>Paxil<\/em> television ad was submitted for              FDA review prior to use, and the Agency raised no objections to the              language at issue.&quot;              <\/p>\n<p align=\"justify\">&quot;GSK strongly stands behind the safety and efficacy of              <em>Paxil<\/em>,&quot; said Stout. &quot;Physician organizations like the              American Psychiatric Association have stated that antidepressants              are <strong><font color=\"#200020\">not habit forming<\/font><\/strong>. It is also              important to note that the Court has made <strong><font color=\"#200020\">no finding that              <em>Paxil<\/em> is addictive or induces dependency<\/font><\/strong>.&quot;              <\/p>\n<p align=\"justify\"><em>Paxil<\/em> is a leading selective serotonin reuptake inhibitor              (SSRI) indicated for the treatment of depression and all major              anxiety disorders including social anxiety disorder, panic disorder,              obsessive compulsive disorder, generalized anxiety disorder and              post-traumatic stress disorder.              <\/p>\n<div align=\"justify\">GlaxoSmithKline, one of the world&#8217;s leading research-based              pharmaceutical and health care companies, is committed to fighting              disease by bringing innovative medicines and services to patients              and to the health care providers who serve them. U.S. headquarters              are in Philadelphia, PA, and Research Triangle Park, N.C.              <\/div>\n<hr size=\"1\" \/><\/td>\n<\/tr>\n<tr>\n<td><strong><font color=\"#200020\">Editor&#8217;s Note:<\/font><\/strong><\/td>\n<\/tr>\n<tr>\n<td>\n<div align=\"justify\">The  following physicians are available for comment. To arrange an               interview, please contact Sherri Jaffe at 914 656 5479.<\/div>\n<div align=\"justify\">  <\/div>\n<p align=\"justify\"><strong><font color=\"#200020\">Charles  B. Nemeroff<\/font><\/strong> MD, PhD, Reunette W. Harris Professor and               Chairman, Department of Psychiatry and Behavioral Sciences, Emory               University School of Medicine<\/p>\n<div align=\"justify\">  <\/div>\n<p align=\"justify\"><strong><font color=\"#200020\">Alan  F. Schatzberg<\/font><\/strong> MD, Professor and Chairman, Department of               Psychiatry and Behavioral Sciences, Stanford University Medical               School<\/p>\n<div align=\"justify\">   <\/div>\n<p align=\"justify\"><strong><font color=\"#200020\">Vivien  K. Burt<\/font><\/strong> MD, PhD, Professor of Clinical Psychiatry, UCLA               School of Medicine; Director, Women&#8217;s Life Center, UCLA               Neuropsychiatric Institute and Hospital<\/p>\n<div align=\"justify\">  <\/div>\n<p align=\"justify\"><strong><font color=\"#200020\">David V Sheehan<\/font><\/strong> MD, MBA, Professor of Psychiatry, University of              South Florida College of Medicine, Tampa Florida<\/p>\n<hr size=\"1\" \/>\n<div align=\"justify\">                <sup>&quot;Let&#8217;s Talk Facts About              Depression,&quot; American Psychiatric  Association,               http:\/\/www.psych.org\/public_info\/depression.cfm              <\/sup> <\/div>\n<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">In the 2001 ad above, they say, &quot;<em>Paxil is non-habit forming<\/em>.&quot; In the 2002 version, they say, &quot;<em>Paxil is non-habit forming<\/em>,&quot; but add, &quot;<em>Don&#8217;t stop taking Paxil before talking to your doctor<\/em>.&quot; Those are the ads that lead to the ruling referred to in the press release:<\/p>\n<p align=\"justify\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" border=\"0\" align=\"right\" hspace=\"4\" height=\"166\" src=\"http:\/\/1boringoldman.com\/images\/ssri-2.gif\" \/>The person that got me focused on this topic actually started on Paxil in 2002 when she was 14 years old. By 2002, withdrawal obviously wasn&#8217;t well enough known publicly to keep people from starting patients on it. In 2002, the Internet wasn&#8217;t full of personal reports, e-books about getting off of it, or youtube advice videos. At that time, Paxil was in its prime. Drs. Nemeroff and Schatzberg had signed on to a ghost-written <a href=\"http:\/\/1boringoldman.com\/index.php\/2010\/12\/01\/roaches\/\" target=\"_blank\"><u><strong><font color=\"#200020\">textbook<\/font><\/strong><\/u><\/a> a couple of years before that was being handed out to Primary Care Physicians leaning doctors towards Paxil. Dr. Martin Keller et al had just published a <a href=\"http:\/\/1boringoldman.com\/index.php\/2011\/05\/07\/retract-study-329\/\" target=\"_blank\"><u><strong><font color=\"#200020\">paper<\/font><\/strong><\/u><\/a> claiming it was effective in depressed adolescents. That was the infamous Study 329 now widely discredited that failed to mention the akisthisia and the suicidal thoughts in that age group. 2002 was also the year when the BBC program, <strong><font color=\"#660033\">Panorama<\/font><\/strong>, did a <a target=\"_blank\" href=\"http:\/\/news.bbc.co.uk\/2\/hi\/programmes\/panorama\/2982797.stm\"><u><strong><font color=\"#200020\">series<\/font><\/strong><\/u><\/a>  on Paxil [Seroxat] in October.  The program received 1400 emails in response [still available on their <u><a target=\"_blank\" href=\"http:\/\/news.bbc.co.uk\/2\/hi\/programmes\/panorama\/2991893.stm\"><strong><font color=\"#200020\">website<\/font><\/strong><\/a><\/u>] and was a wake-up call for many. ABC Primetime did a similar series here in 2004 [ <a target=\"_blank\" href=\"http:\/\/abcnews.go.com\/Health\/story?id=311956&#038;page=1\"><u><strong><font color=\"#200020\">Drug Maker Withheld Paxil Study Data<\/font><\/strong><\/u><\/a>  ]. But 2002 was still an arrogant time at GSK, in spite of the growing disquiet.<\/p>\n<div align=\"justify\">And the bloggers increasingly emerged with their personal stories of Paxil [Seroxat] withdrawal &#8211; for example <strong><a target=\"_blank\" href=\"http:\/\/seroxatsecrets.wordpress.com\/\"><font color=\"#200020\">Seroxat secrets&#8230;<\/font><\/a><\/strong> Bob&#8217;s blogroll lists the many others:<\/div>\n<blockquote>\n<div align=\"center\"><strong><a target=\"_blank\" href=\"http:\/\/seroxatsecrets.wordpress.com\/2006\/12\/page\/2\/\"><font color=\"#200020\">The start of it all<\/font><\/a><\/strong><br \/>      <strong><a target=\"_blank\" href=\"http:\/\/seroxatsecrets.wordpress.com\/\"><font color=\"#6666ff\">Seroxat secrets&#8230;<\/font><\/a><\/strong><br \/>      by Bob Fiddaman<br \/>      December 18, 2006<\/div>\n<p align=\"justify\"><sup>I  first took Seroxat [Paxil in the USA] in 1997. I finally decided to   stop taking it in May 2004 and it then took me 22 months to slowly wean   off the drug. All in all I have lost almost 10 years of my life to this   drug. I want to share with you what I&rsquo;ve found out since May 2004.  I&rsquo;ve  discovered how dangerous SSRIs can be and how dangerous the big  drug  companies are &ndash; especially GlaxoSmithKline [who make Seroxat].<\/sup><\/p>\n<p align=\"justify\"><sup>I  think at this point I must mention the drug regulators here in the  UK [The MHRA] and the FDA in America. If you&rsquo;re new to all this you  might  think they are the organisations that we can trust to keep us safe  from  nightmare drugs like Seroxat. Not the case I&rsquo;m afraid.<\/sup><\/p>\n<div align=\"justify\"><sup>The  public has been let down by them on all too many occasions. I&rsquo;ve   become very cynical since May 2004 and as I&rsquo;ve learnt more and more and I   have to say it looks from here as if the MHRA and The FDA are more   concerned with protecting the Pharmaceutical companies than protecting   the public. There&rsquo;s a lot of money to be made from selling new drugs to  the world  &ndash; a lot of money indeed. It doesn&rsquo;t seem to matter if the  drugs don&rsquo;t  quite work as well as they should or if people can become  addicted to  them. In the case of Seroxat, Glaxo has simply hidden trial  data that  shows how dangerous Seroxat really is. In this Blog I&rsquo;ll be  naming and shaming the guilty and I&rsquo;ll be telling the truth about  Seroxat.<\/sup><\/div>\n<\/blockquote>\n<p>     Here&#8217;s what Dr. David Healy had to say about Paxil Withdrawal in his 2004 book, <u><strong><font color=\"#200020\">Let Them Eat Prozac<\/font><\/strong><\/u> [page 270]:                   <\/p>\n<ul>\n<div align=\"justify\"><sup>Until very recently, Glaxo-Smith-Klein said &quot;withdrawal&quot; reactions are rare on Paxil, and when they do happen, they are mild and self limiting. But now it seems that these drugs, which were not supposed to cause dependence because they were &quot;antidepressants&quot; cause more serious dependence than the benzodiazepines ever did&#8230; Long before Paxil came to market, as I became aware while accessing SmithKline&#8217;s archive in the <em>Tobin<\/em> case in March 2001, SmithKline was aware that healthy volunteers who had only been taking Paxil for a few weeks had difficulties on withdrawal. In the mid-1980s, SmithKline had run healthy volunteer studies in which a large portion of the volunteers had distinct withdrawal syndromes after a brief exposure to paroxetine. These details, including the death of one volunteer have not been published&#8230;<\/sup><\/div>\n<\/ul>\n<div align=\"justify\">In fact, &quot;Withdrawal&quot; was used to SmithKline&#8217;s advantage:<\/div>\n<ul>\n<div align=\"justify\"><sup>Despite this, SmithKline designed long-term treatment trials in which patients who had responded to Paxil were re-randomized to either continuing Paxil or a switch to placebo. Similar studies were carried out on Zoloft. The difficulties of those switching to placebo were interpreted as new illness episodes, and on this basis the companies were granted licenses to claim that Paxil and Zoloft were prophylactic in depression&#8230;<\/sup><\/div>\n<\/ul>\n<div align=\"justify\">   I&#8217;ve just touched the tip of the iceberg of the voluminous literature now documenting GSK&#8217;s deceit about Paxil withdrawal [among other things]. One might say, &quot;Why keep bringing it up? 2002 was a long time ago.&quot; Well, it didn&#8217;t feel like a long time ago to me yesterday when I was talking to my friend&#8217;s daughter who had spent the night before in an Emergency Room being treated for the symptoms she developed after trying, once again, to get off the drug she&#8217;s been on for nine years. It felt like right now&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Paxil ad from 2001 Paxil ad from 2002 I just received a copy of a GSK Press Release from 2002, obviously published in response to the ruling in the last post. It speaks to a lot of things, but the central point is how corrupt things had become by then. They still had four years [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-15237","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/15237","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=15237"}],"version-history":[{"count":31,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/15237\/revisions"}],"predecessor-version":[{"id":15304,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/15237\/revisions\/15304"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=15237"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=15237"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=15237"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}