{"id":21693,"date":"2012-03-30T17:25:04","date_gmt":"2012-03-30T21:25:04","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=21693"},"modified":"2012-03-30T20:46:54","modified_gmt":"2012-03-31T00:46:54","slug":"the-best-of-times","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2012\/03\/30\/the-best-of-times\/","title":{"rendered":"the best of times&#8230;"},"content":{"rendered":"<br \/>\n<blockquote>\n<div align=\"center\"><u><strong><a href=\"http:\/\/blogs.plos.org\/speakingofmedicine\/2012\/03\/26\/conflicts-of-interest-and-dsm-5-the-media-reaction\/\" target=\"_blank\"><font color=\"#200020\">Conflicts of interest and DSM-5: the media reaction<\/font><\/a><\/strong><\/u><br \/>          <strong><font color=\"#200020\">PLoS<\/font><\/strong><br \/>          By Clare Weaver<br \/>          March 26, 2012<\/div>\n<p>   <\/p>\n<div align=\"justify\"><sup>The fifth edition of the American Psychiatric Association&rsquo;s <em>Diagnostic and Statistical Manual of Mental Disorders <\/em><em>(DSM-5)<\/em><em> <\/em>will  be published next year, but concerns surround its financial competing  interest disclosure policy and the ties its panel members have to drug  companies. Last week <em>PLoS Medicine<\/em> published an <u><strong><a href=\"http:\/\/www.plosmedicine.org\/article\/info%3Adoi%2F10.1371%2Fjournal.pmed.1001190\" target=\"_blank\"><font color=\"#200020\">analysis by Lisa Cosgrove and Sheldon Krimsky<\/font><\/a><\/strong><\/u>  , who examined the disclosure policy and the panel members&rsquo; conflicts  of interest, and call for the APA to make changes to increase  transparency before the manual&rsquo;s publication.<\/p>\n<p>           Within three days of publication the paper had been viewed over 4000  times, and several major media outlets reported on the authors&rsquo; findings  and the wider issues they relate to. In the news section of<u><strong> <a href=\"http:\/\/www.nature.com\/news\/industry-ties-remain-rife-on-panels-for-psychiatry-manual-1.10206\" target=\"_blank\"><em><font color=\"#200020\">Nature<\/font><\/em><\/a><\/strong><\/u>,  Heidi Ledford drew attention to the fact that panel members with  competing interests are not evenly distributed throughout the panel work  groups, commenting that &ldquo;the committees with the highest number of  industrial links are those evaluating conditions for which drugs are the  first-line treatment.&rdquo; She also described the failure of the policy to  require its panel members to specify participation in speakers&rsquo; bureaus,  arrangements &ldquo;in which a company hires someone to give a presentation  about its product.&rdquo;<\/p>\n<p>           The DSM-5 is unpopular for reasons other than its panel members&rsquo; competing interests. Peter Aldhous at <u><strong><a href=\"http:\/\/www.newscientist.com\/article\/dn21580-many-authors-of-psychiatry-bible-have-industry-ties.html\" target=\"_blank\"><em><font color=\"#200020\">New Scientist<\/font><\/em><\/a><\/strong><\/u>  reported on the controversial changes to certain diagnostic categories,  such as the mood disorders group, &ldquo;which proposes including bereaved  people in the definition of major depression,&rdquo; and adds that, according  to critics, &ldquo;definitions of psychiatric illnesses have broadened over  successive editions of the manual as a result of pressure from the  pharmaceutical industry.&rdquo; He also discusses the criticism the DSM  proposals have attracted from psychologists, who &ldquo;tend to favour  counselling over the drug treatments that dominate modern psychiatry,&rdquo;  and links to an <u><strong><a target=\"_blank\" href=\"http:\/\/www.ipetitions.com\/petition\/dsm5\/\"><font color=\"#200020\">online petition<\/font><\/a><\/strong><\/u> calling for greater involvement from psychologists in the DSM-5. Katie Moisse at <u><strong><a href=\"http:\/\/abcnews.go.com\/Health\/MindMoodNews\/dsm-fire-financial-conflicts\/story?id=15909673#.T2mc4rKJUdV\" target=\"_blank\"><em><font color=\"#200020\">ABC News<\/font><\/em><\/a><\/strong><\/u>  quotes David Elkins, president of the American Psychological  Association&rsquo;s society for humanistic psychology and chairman of the  committee responsible for the petition, who is &ldquo;dismayed&rdquo; that seven in  10 DSM-5 task force members have drug company ties.&rdquo;<\/p>\n<p>           Writing for <u><strong><a href=\"http:\/\/californiawatch.org\/dailyreport\/mental-health-panel-has-ties-drugmakers-15339\" target=\"_blank\"><em><font color=\"#200020\">California Watch<\/font><\/em><\/a><\/strong><\/u>,  Bernice Young highlighted the authors&rsquo; findings &ndash; that the proportion  of the DSM-5 panel with financial conflicts of interest between 2006 and  2011 stands at 69% &ndash; and provided a link to the APA&rsquo;s <u><strong><a href=\"http:\/\/www.psych.org\/MainMenu\/Newsroom\/NewsReleases\/2012-News-Releases\/Statement-from-APA-President-John-M-Oldham-MD-on-PLoS-Article.aspx?FT=.pdf\" target=\"_blank\"><font color=\"#200020\">refutation of the paper&rsquo;s conclusions<\/font><\/a><\/strong><\/u>.  This includes a statement saying that many members have now divested  themselves of previously declared competing interests, and that in fact,  for 2012, 72% of panel members declare no financial ties to industry&#8230;<\/sup><\/div>\n<\/blockquote>\n<blockquote>\n<div align=\"center\"><a href=\"http:\/\/blog.oup.com\/2012\/03\/dsm-5-proposals-for-generalized-anxiety-disorder\/\" target=\"_blank\"><u><strong><font color=\"#200020\">DSM-5 Proposals for Generalized Anxiety Disorder<\/font><\/strong><\/u><\/a><br \/>        <strong><font color=\"#200020\">OUPblog <\/font><\/strong><br \/>          By Allan V. Horwitz<br \/>        March 28th, 2012<\/div>\n<p>       <\/p>\n<div align=\"justify\"><sup>&#8230;Nevertheless, the proposed  changes in the Generalized Anxiety Disorder (GAD) have been relatively neglected. Changes in the GAD category are potentially the most important  because they would impact the largest number of people. Anxiety  disorders are the single most common class of mental disorders in the  population and, historically, GAD has been the central anxiety disorder.  The changes that the <em>DSM-5<\/em> anxiety working group proposes for  GAD have the potential to massively increase the number of people  subject to GAD diagnosis and, correspondingly, the number of people at  risk for false positive diagnoses of GAD. <\/p>\n<p>       The <em>DSM-III<\/em>, following Freud,  had defined Generalized Anxiety Disorder as a &ldquo;generalized, persistent&rdquo;  condition that lacked the more specific symptoms characterizing the  other anxiety disorders. It also made it a residual condition that  couldn&rsquo;t be diagnosed in the presence of other anxiety or depressive  conditions, so that its actual prevalence was quite low: patients who  met GAD criteria typically also met criteria for other disorders. The <em>DSM-III-R<\/em>  (1986) abandoned the hierarchical rule that disallowed GAD diagnoses in  the presence of other disorders. It also transformed the nature of GAD  from generalized anxiety to a focus on specific worries, stating: <\/sup><\/div>\n<ul>\n<div align=\"justify\"><sup>Unrealistic or excessive anxiety and worry (apprehensive  expectation) about two or more life circumstances, e.g. worry about  possible misfortune to one&rsquo;s child (who is in no danger) and worry about  finances (for no good reason), for a period of six months or longer,  during which the person has been bothered more days than not by these  concerns.<\/sup><\/div>\n<\/ul>\n<div align=\"justify\"><sup>The central place this definition accords to worries not only changed  the core nature of the diagnosis but also &mdash; given the omnipresence of  things that people have to worry about &mdash; could potentially pathologize  common anxious conditions. However, the many qualifiers such as &ldquo;two or  more life circumstances&rdquo; and examples of limiting diagnoses to anxiety  about children who are &ldquo;in no danger&rdquo; or about finances &ldquo;for no good  reason&rdquo; clearly distinguished realistic worries from anxiety disorders.  The <em>DSM-III-R <\/em>also required that symptoms must endure for six  months, reducing the possibility that purely situational anxiety would  be misdiagnosed as GAD. For the most part, the <em>DSM-IV<\/em> maintained the <em>DSM-IIIR<\/em> criteria for GAD. <\/p>\n<p>            The <em>DSM-5<\/em> proposals for Generalized Anxiety Disorder run the  risk of extensively pathologizing what could become an extraordinarily  common disorder. They would lower the duration and severity thresholds  for GAD from six to three months and from three of six to one of four  symptoms, respectively. Moreover, they lack the contextual qualifiers  that the <em>DSM-IIIR<\/em> had used to distinguish disordered from  natural worries: &ldquo;Excessive anxiety and worry (apprehensive expectation)  about two (or more) domains of activities or events (for example,  domains like family, health, finances, and school\/work difficulties).&rdquo;  Worse, the types of worries these criteria specify are exactly the most  common concerns in the population, so that lower thresholds have the  potential to vastly increase the number of people subject to this  diagnosis. The criteria leave unclear what the meaning of &ldquo;excessive&rdquo; is  &mdash; patient self-definition, social norms, clinician judgment, etc. &mdash; so  this qualifier does not provide much help in limiting false positives.  Given the ubiquity  of common worries in the population, these lower thresholds could pave  the way for GAD to replace depression as the most common diagnosis of  twenty-first century psychiatry.<\/p>\n<p>            In certain respects, the <em>DSM-5<\/em> recommendations for  Generalized Anxiety Disorder reverse the ages old dictum that mental  disorders must be without cause, that is, not understandable in terms of  the person&rsquo;s actual life situation. From Hippocrates through the <em>DSM-IV<\/em>  definition of mental illness, worries about family, health, finances,  or work would have been excluded from the domain of mental disorders.  Indeed, they are the very model of conditions that arise with cause. The  <em>DSM-5<\/em> proposals for GAD could classify even the most understandable sorts of worries as mental disorders.<\/sup><\/div>\n<\/blockquote>\n<blockquote>\n<div align=\"center\"><a href=\"http:\/\/www.huffingtonpost.com\/allen-frances\/behavioral-addiction_b_1215967.html\" target=\"_blank\"><u><strong><font color=\"#200020\">Do We All Have Behavioral Addictions? <\/font><\/strong><\/u><\/a><br \/>      <strong><font color=\"#200020\">Huffington Post<\/font><\/strong><br \/>      by Allen Frances<br \/>      03\/28\/2012<\/div>\n<p>    <\/p>\n<div align=\"justify\"><sup>  The relentless march to medicalize normality out of existence  is opening a new and especially ridiculous front.  The DSM-5 suggests  providing a new section for &quot;behavioral addictions.&quot;  The category would  begin life nested alongside the substance addictions and would start  with just one disorder (gambling). Fortunately, none of the other  &quot;behavioral addictions&quot; suggested for DSM-5 would gain official status  as stand-alone diagnoses. But if a clinician felt that someone were  &quot;addicted&quot; to sex, or to shopping, or to the Internet, or to working, or  to video games, or to model railroading, or to whatever else (the list  is long and could easily expand into every area of popular activity),  this could be diagnosed as &quot;Behavioral Addiction Not Otherwise  Specified&quot; and thus receive the dignity of an official DSM code. This  Pandora&#8217;s Box of diagnostic possibilities could turn all  manner of  passionate interests into psychiatric illnesses&#8230;<\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">I love reading things like this. While it might seem discouraging to many that there are so many things wrong right now &#8211; the DSM-Task Force debacle, J&amp;J Trials monthly, blogs everywhere cataloging deceitful science &#8211; <strong><font color=\"#200020\">this is the best of times<\/font><\/strong>. All of this stuff has been going on for years, actually for decades. If you&#8217;re a 70 year old me, the fact that it&#8217;s being talked about and visible in open court, and on Huffington Post and Reuters and the New York Times, is just plain remarkable. In my case, if I said anything about it for the twenty years before this, I was immediately discounted because I was a psychoanalyst [we were the last bad guys]. Nobody says that anymore. It&#8217;s almost like I finally get to be a psychiatrist again &#8211; even though I never stopped being one from my perspective.<\/div>\n<p align=\"justify\">I&#8217;m a southerner, born in 1941 just before Pearl Harbor. I love the South and grew up standing when they played Dixie. I didn&#8217;t know how fortunate I was to grow up in an anti-racist family. My father was an immigrant Italian who had felt the sting of prejudice and my mother was a Georgia Peach, but she had a father who had quit the Klan as a young man and made &quot;the change&quot; in a big way. The open &quot;trouble&quot; in the South started when I was in high school, and by college, I was on board the Civil Rights train, as was my mother, as was my now wife who I met in Medical School. I remember the days in the mid-1960s when it finally became okay to be on that train. It started slowly, but then built steadily. From where I sat, it started changing when those four little girls were killed in the Birmingham bombing, and it has crept upward since.<\/p>\n<p align=\"justify\">I think of that now because it&#8217;s discouraging when we look at the abysmal behavior of the DSM-5 Task Force, or read things like my last post where an article that shouldn&#8217;t have been published is touted so highly. I feel discouraged when I look at the APA Meeting Brochure and see people presenting who I think should&#8217;ve been removed from the membership roster altogether. But then a friend down the road calls for me to turn on CBS Sunday Morning because they&#8217;re talking about antidepressants, or when I run across an article in the Press without even looking for it about the antipsychotics. The reason <strong><font color=\"#200020\">this is the best of times<\/font><\/strong> is that this is what it feels like when things begin to change. It always feels this way. Discouraging. Too slow. <em>They<\/em> are too powerful. <em>They<\/em> act as if nothing needs changing.<\/p>\n<p align=\"justify\">Segregation, Women&#8217;s Rights, Johnson&#8217;s Viet Nam, Bush&#8217;s Iraq, Gay Rights, now Pharma&#8217;s psychiatry &#8211; these things come in waves. Just few more insiders [like Allen Frances], the clear unearthing of a few more scandals [plenty to chose from], another Senator Grassley or two [very key], and the pace will pick up &#8211; wait and see. The other reason <strong><font color=\"#200020\">this is the best of times<\/font><\/strong>, is that once things become clear to enough people at large, then you&#8217;ve got to do something about what&#8217;s wrong, and that&#8217;s plenty tricky, shoals everywhere. So <strong><font color=\"#200020\">this is the best of times<\/font><\/strong> right now because all we have to do is keep pointing out what&#8217;s wrong &#8211; which is a piece of cake compared to what comes next.<\/p>\n<div align=\"justify\">When I was a boy, I used to marvel at how the old people thought. Something would come up and the adults would be up in arms, but the old people weren&#8217;t. They&#8217;d talk about the Depression, or FDR, or WWII or something equally historic. They&#8217;d seen the world not come to an end enough times and could sit in front of a television and remember the first radio they ever heard. There was a balance unavailable to the younger adults. I may not be old enough for that much perspective, but I&#8217;m old enough to know that the strangle-hold the pharmaceutical industry and their misguided friends have had on the mental health world is on the wane. It has been a very long wait. I honestly didn&#8217;t think I&#8217;d ever even see it at all&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Conflicts of interest and DSM-5: the media reaction PLoS By Clare Weaver March 26, 2012 The fifth edition of the American Psychiatric Association&rsquo;s Diagnostic and Statistical Manual of Mental Disorders (DSM-5) will be published next year, but concerns surround its financial competing interest disclosure policy and the ties its panel members have to drug companies. 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