{"id":23422,"date":"2012-05-17T16:39:02","date_gmt":"2012-05-17T20:39:02","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=23422"},"modified":"2012-05-17T16:39:02","modified_gmt":"2012-05-17T20:39:02","slug":"the-dreams-of-our-fathers-viii","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2012\/05\/17\/the-dreams-of-our-fathers-viii\/","title":{"rendered":"the dreams of our fathers VIII&#8230;"},"content":{"rendered":"\n<div align=\"justify\">So I&#8217;ll begin winding up this journey by starting over. The Psychiatric Department ay Washington University in St. Louis in the 1960s stood as the center of Bological Psychiatry in America. They thought psychoanalysis, a dominant paradigm at the time, had no place in psychiatry either as theoretical base or as political force in organized psychiatry. They particularly opposed the inclusion of the Neuroses in the 1968 DSM-II. Shortly after it was published they published an article [<strong><font color=\"#200020\">Establishment of Diagnostic Validity in Psychiatric Illness: Its Application to Schizophrenia<\/font><\/strong>] with these comments [<strong><font color=\"#990000\">quoted in full this time for a reason<\/font><\/strong>]:<\/div>\n<blockquote>\n<div align=\"justify\"><sup>One of the reasons that diagnostic classification has fallen into disrepute among some psychiatrists is that diagnostic schemes have been largely based upon a priori principles rather than upon systematic studies. Such systematic studies are necessary, although they may be based upon different approaches. We have found that the approach described here facilitates the development of a valid classification in psychiatry. This paper illustrates its usefulness in schizophrenia.<br \/>              <u><strong><font color=\"#200020\">The Five Phases<\/font><\/strong><\/u><br \/>              1.Clinical Description<br \/>              In general, the first step is to describe the clinical picture of the disorder. This may be a single striking clinical feature or a combination of clinical features thought to be associated with one another. Race, sex, age at onset, precipitating factors, and other items may be used to define the clinical picture more precisely. The clinical picture thus does not include only symptoms.<br \/>              2. Laboratory Studies<br \/>              Included among laboratory studies are chemical, physiological, radiological, and anatomical (biopsy and autopsy) findings. Certain psychological tests, when shown to be reliable and reproducible, may also be considered laboratory studies in this context. Laboratory findings are generally more reliable, precise, and reproducible than are clinical descriptions. When consistent with a defined clinical picture they permit a more refined classification. Without such a defined clinical picture, their value may be considerably reduced. Unfortunately, consistent and reliable laboratory findings have not yet been demonstrated in the more common psychiatric disorders.<br \/>            3. Delimitation from Other Disorders<br \/>            Since similar clinical features and laboratory findings may be seen in patients suffering from different disorders (e.g., cough and blood in the sputum in lobar pneumonia, bronchiectasis, and bronchogenic carcinoma), it is necessary to specify exclusion criteria so that patients with other illnesses are not included in the group to be studied. These criteria should also permit exclusion of borderline cases and doubtful cases (an undiagnosed group) so that the index group may be as homogeneous as possible.<br \/>            4. Follow-Up Study<br \/>            The purpose of the follow-up study is to determine whether or not the original patients are suffering from some other defined disorder that could account for the original clinical picture. If they are suffering from another such illness, this finding suggests that the original patients did not comprise a homogeneous group and that it is necessary to modify the diagnostic criteria. In the absence of known etiology or pathogenesis, which is true of the more common psychiatric disorders, marked differences in outcome, such as between complete recovery and chronic illness, suggest that the group is not homogeneous. This latter point is not as compelling in suggesting diagnostic heterogeneity as is the finding of a change in diagnosis. The same illness may have a variable prognosis, but until we know more about the fundamental nature of the common psychiatric illnesses marked differences in outcome should be regarded as a challenge to the validity of the original diagnosis.<br \/>            5. Family Study<br \/>            Most psychiatric illnesses have been shown to run in families, whether the investigations were designed to study hereditary or environmental causes. Independent of the question of etiology, therefore, the finding of an increased prevalence of the same disorder among the close relatives of the original patients strongly indicates that one is dealing with a valid entity. We hope it is apparent that<\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">As we&#8217;ve seen, one on their residents, John Feighner, took it upon himself to construct a taxonomy for psychiatry with their help from the literature based on signs and symptoms which they published [<a target=\"_blank\" href=\"http:\/\/www.scalesandmeasures.net\/files\/files\/Feighner_JP_1972.pdf\"><u><strong><font color=\"#200020\">Diagnostic Criteria for Use in Psychiatric Research<\/font><\/strong><\/u><\/a> &#8211; <a target=\"_blank\" href=\"http:\/\/www.scalesandmeasures.net\/files\/files\/Feighner_JP_1972.pdf\"><u><strong><font color=\"#200020\">full text on-line<\/font><\/strong><\/u><\/a>]. It was a deceptive article requiring a close reading. In an early paragraph, they lodged their complaint about the current system:<\/div>\n<blockquote>\n<div align=\"justify\"><sup>In contrast to the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders (DSM-II), in which the diagnostic classification is based upon the &quot;best clinical judgement and experience&quot; of a committee and its consultants, this communication will present a diagnostic classification validated primarily by follow-up and family studies. The following criteria for establishing diagnostic validity in psychiatric illness have been described elsewhere and may be divided into five phase.<\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">Then <strong><font color=\"#200020\">they included the section from their former paper verbatim<\/font><\/strong>, literally word-for-word. I&#8217;ve never seen that in a published paper. Next came the report of two unpublished studies showing high inter-rater reliability, that apparently used some other version of a diagnostic system and could only have antedated John Feighner&#8217;s compilation. Then came what are known as the Feighner Criteria. On the first several readings, I didn&#8217;t know that:<\/div>\n<ul><sup>         <\/p>\n<li>\n<div align=\"justify\">John Feighner was a psychiatery resident<\/div>\n<\/li>\n<li>\n<div align=\"justify\">The criteria came from a literature search, not their own patients<\/div>\n<\/li>\n<li>\n<div align=\"justify\">The criteria were hypothetical and had not been vetted by their 5 phases<\/div>\n<\/li>\n<li>\n<div align=\"justify\">The five phases of diagnosis were not part of generating the criteria but rather cut and pasted from their earlier article<\/div>\n<\/li>\n<li>\n<div align=\"justify\">The reliability figures were from somewhere else antedating the criteria [never ever published]<\/div>\n<\/li>\n<p>         <\/sup><\/ul>\n<div align=\"justify\">Since I figured those things out by going over and over it boring any reader of this series to tears, I find that others already knew it, but it sure wasn&#8217;t apparent to me. I can&#8217;t exactly call that lying, but I would be glad to call it conscious deception. It matters because this diagnostic system became the paradigm for an evidence-based phenomenological approach to psychiatric diagnosis &#8211; <strong><font color=\"#200020\">validity<\/font><\/strong> certified by their mentioned phases and <strong><font color=\"#200020\">reliability<\/font><\/strong> tested in the field &#8211; none of which ever happened.<\/div>\n<p align=\"justify\">For Dr. Spitzer, charged with the task of redesigning the DSM-II, the Feighner Criteria were a godsend. They gave him a descriptive system to work with and allies who shared his disaffection with the psychoanalysts and their influence on the DSM-II. In his 1974 meta-analysis using Kappa, he demonstrated the unreliability of the DSM-II system and introduced the Feighner Criteria as a template for the Research Diagnostic Criteria [RDC] being tested in an NIMH study with Dr. Robins, a leader of the St. Louis Group [<u><strong><a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2012\/05\/08\/box-scores\/\"><font color=\"#200020\">box scores and kappa&hellip;<\/font><\/a><\/strong><\/u>]. In 1978, they published reliability studies for the RDC and the DSM was born [<u><strong><a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2012\/05\/12\/the-dreams-of-our-fathers-i\/\"><font color=\"#200020\">the dreams of our fathers I&hellip;<\/font><\/a><\/strong><\/u>]. In 1991, in response to challenges that his criteria in the DSM-III had not followed the phases described in these early papers, Dr. Spitzer admitted that they had not validated the catergories as described by Robins and Guze, but continued to contend that there was no etiological bias towards biology, a point he made again in 2001 [<u><strong><a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2012\/05\/13\/dreams-of-our-fathers-ii\/\"><font color=\"#200020\">dreams of our fathers II&hellip;<\/font><\/a><\/strong><\/u>].<\/p>\n<p align=\"justify\">In poring over this, I&#8217;ve come to see this process as having two distinct dreams. Everybody involved wanted the psychoanalytic influence gone. John Feighner was an young resident who dreamed of making concrete sense of psychiatric diagnosis using the literature to build a phenomenological template. Robert Spitzer had the same goal &#8211; a descriptive DSM-III like the one he created. He says he didn&#8217;t have an etiologic focus or bias. So I lump the two of them together. The St. Louis Group at Barnes Hospital had a definite etiologic focus &#8211; biology, data, biology. They dreamed of picking up where Kraepelin left off and building not only a neo-Kraepelinian DSM-III, but a neo-Kraepelinian psychiatry: <\/p>\n<ul>\n<div align=\"justify\"><sup>1. Psychiatry is a branch of medicine. <\/sup><\/div>\n<div align=\"justify\"><sup>2. Psychiatry should utilize modern scientific methodologies and base its practice on scientific knowledge.<\/sup><\/div>\n<div align=\"justify\"><sup>3. Psychiatry treats people who are sick and who require treatment.<\/sup><\/div>\n<div align=\"justify\"><sup>4. There is a boundary between the normal and the sick.<\/sup><\/div>\n<div align=\"justify\"><sup>5. There are discrete mental illnesses.&nbsp; They are not myths, and there are many of them.<\/sup><\/div>\n<div align=\"justify\"><sup>6. The focus of psychiatric physicians should be on the biological aspects of illness.<\/sup><\/div>\n<div align=\"justify\"><sup>7. There should be an explicit and intentional concern with diagnosis and classification.<\/sup><\/div>\n<div align=\"justify\"><sup>8. Diagnostic criteria should be codified, and a legitimate and valued area of research should be to validate them.<\/sup><\/div>\n<div align=\"justify\"><sup>9. Statistical techniques should be used to improve reliability and validity.<\/sup><\/div>\n<\/ul>\n<div align=\"justify\">And so in 1980, the DSM-III expunged the psychoanalytic\/psychological bent from the diagnostic system and largely from psychiatry while creating a descriptive system that proposed to cover the full territory of mental illness by being etiologically neutral for anything unproven. But the parallel dream of the St. Louis Group, a full scale medical\/biologic system and psychiatry lived on in the white space on the Manual&#8217;s pages. Spitzer&#8217;s dream was realized. The dreams from St. Louis were launched.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>So I&#8217;ll begin winding up this journey by starting over. The Psychiatric Department ay Washington University in St. Louis in the 1960s stood as the center of Bological Psychiatry in America. They thought psychoanalysis, a dominant paradigm at the time, had no place in psychiatry either as theoretical base or as political force in organized [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-23422","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23422","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=23422"}],"version-history":[{"count":10,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23422\/revisions"}],"predecessor-version":[{"id":44670,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23422\/revisions\/44670"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=23422"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=23422"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=23422"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}