{"id":23824,"date":"2012-05-27T08:13:55","date_gmt":"2012-05-27T12:13:55","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=23824"},"modified":"2012-05-27T08:38:49","modified_gmt":"2012-05-27T12:38:49","slug":"a-hard-lesson","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2012\/05\/27\/a-hard-lesson\/","title":{"rendered":"a hard lesson&#8230;"},"content":{"rendered":"<br \/>\n<blockquote>\n<div align=\"center\"><a href=\"http:\/\/www.huffingtonpost.com\/allen-frances\/spitzer-recants-why-cant-_b_1548027.html\" target=\"_blank\"><u><strong><font color=\"#200020\">Spitzer Recants: Why Can&#8217;t APA Admit Mistakes and Correct Them<\/font><\/strong><\/u><\/a><br \/>    <strong><font color=\"#006699\">Huffington Post<\/font><\/strong><br \/>    by Allen Frances<br \/>    05\/26\/2012<\/div>\n<p>    <\/p>\n<div align=\"justify\"><sup>Ben Carey&#8217;s <u><strong><font color=\"#200020\"><a target=\"_blank\" href=\"http:\/\/www.nytimes.com\/2012\/05\/19\/health\/dr-robert-l-spitzer-noted-psychiatrist-apologizes-for-study-on-gay-cure.html?_r=1&#038;emc=eta1\">front page story<\/a><\/font><\/strong><\/u> in the <em>New York Times<\/em> movingly recounts Bob Spitzer&#8217;s apology for an ill-advised study he conducted more than a decade ago. The background is dramatic. Spitzer had been a hero to the gay and  lesbian community because he was the person most responsible for  removing homosexuality from DSM II. Lifting the cloud of mental disorder  from sexual choice was a big step in the civil rights movement that  only now is bringing full equality. I once attended an award dinner  honoring Bob for his contributions to the gay\/lesbian cause. I never saw  a group more appreciative or a recipient so proud. How surprising then that Spitzer would later publish a  methodologically flawed paper suggesting that psychotherapy might have  some value in changing sexual orientation. Bob had serious misgivings  almost immediately when fundamentalists exploited the paper to pursue  their anachronistic agenda. He decided recently to make a very <u><strong><font color=\"#200020\"><a target=\"_blank\" href=\"http:\/\/www.usatoday.com\/news\/health\/story\/2012-05-18\/researcher-apologizes-for-study-of-gay-therapy\/55068504\/1\">public apology<\/a><\/font><\/strong><\/u>.   &quot;I believe I owe the gay community an apology for my study making  unproven claims of the efficacy of reparative therapy. I also apologize  to any gay person who wasted time and energy undergoing some form of  reparative therapy because they believed that I had proven that  reparative therapy works with some `highly motivated&#8217; individuals.&quot;<\/p>\n<p>     Let&#8217;s compare Bob&#8217;s forthrightness to the consistently evasive  stonewalling that has characterized every step in the development of DSM  5. The American Psychiatric Association has a lot to apologize for &#8212;  but instead maintains a doggedly defensive posture that prevents insight  and self correction. Bob was the first to point out the absurdity of the DSM 5  confidentiality agreements and to predict the poor results that would  come from the resulting secretive and closed process. Each of his dire  predictions has turned out to be right on target. DSM 5 badly missed  every one of its <u><strong><font color=\"#200020\"><a target=\"_blank\" href=\"http:\/\/www.huffingtonpost.com\/allen-frances\/dsm-5-freezes-out-its-sta_b_1269838.html\">deadlines<\/a><\/font><\/strong><\/u>  &#8212; then with time running short, it quietly cancelled its quality  control step because publishing profits trumped the public trust of  producing a safe product. No apology for that.<\/p>\n<p>     When its field trial results were unacceptably low by historical  standards, DSM 5 lowered its standards rather than working to improve  its product to meet them. Again no apology. DSM 5 persists in offering proposals that would inappropriately inflict  the label mental disorder on many millions of people now considered  normal. These suggestions are unsupported by science and are strongly  opposed by 51 mental health associations &#8212; but APA continues to refuse  demands for independent external review. The shabby DSM 5 enterprise has reduced the credibility of psychiatry  and the stature of the APA. It may well have forfeited APA&#8217;s right to  continue as custodian of the DSM franchise. Yes, indeed, APA has a lot  to apologize for and DSM 5 has a long way to go before it will be safe  and scientifically sound&#8230;<\/p>\n<p>     And Bob Spitzer has shown the way. A clear parallel can be drawn  between Bob&#8217;s openly apologizing and withdrawing his paper and the need  for APA to apologize and to withdraw its untenable proposals, end its  closed process, and drop its slavish adherence to unrealistic timelines. If a legendary figure like Bob can correct his mistakes, surely the  APA can do the same &#8212; for the sake of protecting our patients and  keeping the mental health field united.<\/p>\n<p>       There is always regret for having made errors along the way, but the  far greater shame is in pressing forward when your own results reveal  them. Inertia is one of the most powerful forces in nature &#8212; it takes  real courage to oppose it. If APA changes gears, none of us is going to  say, &quot;I told you so!&quot; We&#8217;re going to applaud and feel proud that APA is  finally on the right track. As with Bob Spitzer, sometimes the greatest  honor is to admit mistakes and do the very best we can to correct them. If it fails to reform DSM 5 now, the APA leadership will have much  more to apologize for in the future &#8212; to its members, to our  colleagues, and of course most important to our patients.<\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">Psychiatry was under siege in the 1970s on any number of fronts but one of the main areas was the heavy influence of psychoanalysis which was, itself, not amenable to scientific proof. In response, psychiatry rededicated itself to the scientific method and the watchwords <em>evidence-based medicine<\/em> &#8211; hard work given the subjectivity of mental illness itself. It has been a rocky road and we&#8217;ve learned more than we ever wanted to know about the many ways scientific methodology can be twisted and distorted, but the general commitment perseveres. That commitment was launched by the process of the diagnostic revision called the DSM-III released in 1980. I&#8217;ve been reviewing those days in other posts, and while I&#8217;ll find plenty to criticize, I can&#8217;t argue that Dr. Spitzer certainly brought as much of the scientific method as he could muster to the process. The major example is the use of the Kappa Statistic to quantify reliability &#8211; a statistic basically developed to fit the task.<\/div>\n<p align=\"justify\">Psychiatry is again under siege. This time, it&#8217;s not for being unscientific. It&#8217;s because there has been so much deceitful science, pseudoscience, including gross negligence in conflicts of interest and a remarkable amount of <em>data-massage<\/em> and <em>fudging<\/em> in reported studies. And once again, the focus of the siege is on a revision of our diagnostic system. This particular group, the DSM-5 Task Force, actually started its life with the battle-cry of putting psychiatry on an even more solid scientific footing, but the longed-for breakthroughs failed to materialize. And in their own process, they failed to follow one of the cardinal rules of good science &#8211; hands-on attention to procedures and details &#8211; that failure nowhere more apparent than in the recently released Field Trials for reliability which so badly missed the mark.<\/p>\n<p align=\"justify\">One can make a reasonable analogy between the DSM-5 Field Trials and our ubiquitous clinical drug trials. The point was to test the new proposals from the group for reliability. They came up short [attenuated psychosis, mixed anxiety and depression]. But something else happened. The <em>active comparators<\/em> [generalized anxiety disorder, major depressive disorder], diagnoses found reliable in the past, had some of the lowest Kappa values. In clinical trial parlance, <strong><font color=\"#200020\">the Field Trials were a <em>failed study<\/em><\/font><\/strong>. And this is where psychiatry as a science has floundered. This is where rampant <em>data-massage<\/em> and <em>fudging<\/em> has corrupted our whole field.<\/p>\n<p align=\"justify\">A <em>failed study<\/em> is not a <em>negative study<\/em>. In a <em>negative study<\/em>, the new diagnoses would&#8217;ve been declared unreliable, but the reliability of the old standbys would&#8217;ve been maintained. So don&#8217;t add the new proposals to the Manual. This was a <em>failed study<\/em>. New proposals <u>and<\/u> the oldies were unreliable. It doesn&#8217;t matter how much work has gone into things, or how much is riding on the outcome, <strong><font color=\"#200020\">the scientific thing to do is reach no conclusions, and start anew<\/font><\/strong>.<\/p>\n<div align=\"justify\">In the example Dr. Frances uses here, Dr. Spitzer decided he&#8217;d used a flawed methodology and reached a wrong conclusion, so he retracted his study. And that&#8217;s what the DSM-5 Task Force can give to psychiatry at this point &#8211; following the commitment to the rules of science no matter how hard it is. That would be a fine legacy, an example that might do a lot for our morale, our reputation, and our future. It&#8217;s the lesson we badly need to learn&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Spitzer Recants: Why Can&#8217;t APA Admit Mistakes and Correct Them Huffington Post by Allen Frances 05\/26\/2012 Ben Carey&#8217;s front page story in the New York Times movingly recounts Bob Spitzer&#8217;s apology for an ill-advised study he conducted more than a decade ago. The background is dramatic. Spitzer had been a hero to the gay and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-23824","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23824","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=23824"}],"version-history":[{"count":15,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23824\/revisions"}],"predecessor-version":[{"id":23839,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/23824\/revisions\/23839"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=23824"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=23824"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=23824"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}