{"id":24982,"date":"2012-07-05T00:01:34","date_gmt":"2012-07-05T04:01:34","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=24982"},"modified":"2012-07-05T01:33:55","modified_gmt":"2012-07-05T05:33:55","slug":"learnt-from-the-mistakes-that-were-made","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2012\/07\/05\/learnt-from-the-mistakes-that-were-made\/","title":{"rendered":"&#8220;learnt from the mistakes that were made&#8221;&#8230;"},"content":{"rendered":"\n<p align=\"justify\">GSK Study 329 has become the symbol of the corruption of the psychiatric literature [<u><strong><a href=\"http:\/\/1boringoldman.com\/index.php\/2011\/05\/07\/retract-study-329\/\" target=\"_blank\"><font color=\"#200020\">retract study 329&hellip;<\/font><\/a><\/strong><\/u>]. As we all know, The published article concluded, &quot;<strong><font color=\"#200020\">Paroxetine is generally well tolerated and effective for major depression in adolescents<\/font><\/strong>.&quot; Among the <a href=\"http:\/\/www.justice.gov\/opa\/gsk-docs.html\" target=\"_blank\"><u><strong><font color=\"#200020\">documents<\/font><\/strong><\/u><\/a> released with the $3B fining of GSK [<a href=\"http:\/\/www.pharmalot.com\/2012\/07\/biggest-deal-ever-glaxo-pays-3b-for-bad-behavior\/\" target=\"_blank\"><u><strong><font color=\"#200020\">Biggest Deal Ever: Glaxo Pays $3B For Bad Behavior<\/font><\/strong><\/u><\/a>], there were <a href=\"http:\/\/www.justice.gov\/opa\/documents\/gsk\/complaint-ex1.pdf\" target=\"_blank\"><u><strong><font color=\"#200020\">several memos<\/font><\/strong><\/u><\/a> that made it infinitely clear that GSK knew that it was a negative study:<\/p>\n<p align=\"center\"><a href=\"http:\/\/www.justice.gov\/opa\/documents\/gsk\/complaint-ex1.pdf\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"272\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/paxil-329-1.gif\" \/><\/a><\/p>\n<p align=\"center\"><a href=\"http:\/\/www.justice.gov\/opa\/documents\/gsk\/complaint-ex1.pdf\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"310\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/paxil-329-2.gif\" \/><\/a><\/p>\n<p align=\"center\"><a href=\"http:\/\/www.justice.gov\/opa\/documents\/gsk\/complaint-ex1.pdf\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"281\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/paxil-329-3.gif\" \/><\/a><\/p>\n<p align=\"justify\">There have been numerous calls for a retraction of the ghost-written article [published in the <em><strong><font color=\"#400040\">Journal of the Academy of Child and Adolescent Psychiatry<\/font><\/strong><\/em> in 2001] [including <a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/letter-to-dr-andres-martin\/\"><u><strong><font color=\"#200020\">my own<\/font><\/strong><\/u><\/a>]. The most recent appeal was to Brown University itself [<u><strong><a href=\"http:\/\/1boringoldman.com\/index.php\/2012\/02\/03\/why-not-now\/\" target=\"_blank\"><font color=\"#200020\">why not now?&hellip;<\/font><\/a><\/strong><\/u>], but it was rejected:<\/p>\n<table width=\"450\" cellspacing=\"0\" cellpadding=\"2\" border=\"0\" align=\"center\">\n<tr>\n<td align=\"center\"><img decoding=\"async\" width=\"450\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/brown.jpg\" \/>                   <\/td>\n<\/tr>\n<tr>\n<td align=\"center\"><a target=\"_blank\" href=\"http:\/\/www.browndailyherald.com\/u-will-not-support-keller-retraction-1.2694739#.TyxKY-Rq33k\"><u><strong><font color=\"#3a1e1a\">U. will not support Keller retraction<\/font><\/strong><\/u><\/a><br \/>                   by Sahil Luthra<br \/>              February 3, 2012<br \/>           &nbsp;<\/td>\n<\/tr>\n<tr>\n<td align=\"justify\">The University will not support an effort to retract  a controversial  study co-authored by Professor of Psychiatry and Human  Behavior Martin  Keller, wrote Edward Wing, dean of medicine and  biological sciences, in a  recent letter to the global nonprofit Healthy  Skepticism. The study &mdash; commonly referred to as Study 329 &mdash; identified  the drug Paxil  as an effective combatant of adolescent depression.  Since its  publication in 2001, the study has raised concerns due to  findings that  link Paxil to higher rates of suicidal tendencies.<br \/>           &nbsp;<\/td>\n<\/tr>\n<tr>\n<td align=\"justify\"> \tCiting claims that Keller&rsquo;s study intentionally  misrepresented the effectiveness of Paxil  by suppressing data, Healthy  Skepticism asked the University to write  to the Journal of the American  Academy of Child and Adolescent  Psychiatry and request a retraction of  the findings, The Herald reported  in November. Jon Jureidini,  a  co-author of the Healthy Skepticism letters and a professor at the   University of Adelaide in Australia, received Wing&rsquo;s most recent reply   on Monday. In an email to The Herald, Jureidini  wrote that Healthy  Skepticism would not be discouraged by the  University&rsquo;s response,  though he added he was unsure how the group would  proceed. &quot;One hopes  that universities are leaders in moral and scientific  integrity, but  how can they expect students to acquire such values when  their behavior  directly contradicts their stated policies?&quot; wrote  Healthy Skepticism  co-author Leemon  McHenry in an email to The Herald. McHenry is also a  researcher,  lecturer and part-time professor at California State  University in  Northridge&hellip;<\/td>\n<\/tr>\n<\/table>\n<p>  <\/p>\n<div align=\"justify\">In light of this <a href=\"http:\/\/www.pharmalot.com\/2012\/07\/biggest-deal-ever-glaxo-pays-3b-for-bad-behavior\/\" target=\"_blank\"><u><strong><font color=\"#200020\">recent settlement<\/font><\/strong><\/u><\/a> in which GSK admitted its transgressions, it&#8217;s time for this article to finally be retracted:<\/div>\n<blockquote>\n<div align=\"justify\"><sup>In an unusual mea culpa, Glaxo offered the closest statement to an  outright apology that any drugmaker has made to date in response to such  allegations. &ldquo;Today brings to resolution difficult, long-standing  matters for GSK,&rdquo; Glaxo ceo Andrew Witty says in a <u><strong><a href=\"http:\/\/www.gsk.com\/media\/pressreleases\/2012\/2012-pressrelease-1164663.htm\" target=\"_blank\">statement<\/a><\/strong><\/u>.  &ldquo;Whilst these originate in a different era for the company, they cannot  and will not be ignored. On behalf of GSK, I want to express our regret  and reiterate that we have learnt from the mistakes that were made.&rdquo;<\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">So long as that article stands as part of our literature, it&#8217;s hard to buy that they&#8217;ve really &quot;learnt from&quot; their mistakes&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>GSK Study 329 has become the symbol of the corruption of the psychiatric literature [retract study 329&hellip;]. As we all know, The published article concluded, &quot;Paroxetine is generally well tolerated and effective for major depression in adolescents.&quot; Among the documents released with the $3B fining of GSK [Biggest Deal Ever: Glaxo Pays $3B For Bad [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-24982","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/24982","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=24982"}],"version-history":[{"count":9,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/24982\/revisions"}],"predecessor-version":[{"id":24991,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/24982\/revisions\/24991"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=24982"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=24982"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=24982"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}