{"id":31667,"date":"2013-01-04T08:00:36","date_gmt":"2013-01-04T13:00:36","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=31667"},"modified":"2013-01-04T05:39:27","modified_gmt":"2013-01-04T10:39:27","slug":"speaking-of-persistence","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2013\/01\/04\/speaking-of-persistence\/","title":{"rendered":"speaking of persistence&#8230;"},"content":{"rendered":"<div align=\"justify\">I had a long and complicated look at Major Depressive Disorder, the Bereavement Exclusion, and the proposal to remove it in the DSM-5 a few days ago [<a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2012\/12\/31\/the-what-is-absurd\/\">the <em>what<\/em> is absurd&hellip;<\/a>]. I realized how angry I am that they want to take out the Bereavement Exclusion yet neglect their real task &#8211; revising the whole category [MDD]. I proposed [along with many before me] that MDD itself is a remnant of a political negotiation from long ago rather than a real psychiatric disorder. Adding Grief into the already overcrowded MDD neighborhood seems insulting to patients and colleagues, over and above being irrational. It is so predictably an open invitation for overmedication that their motives and logic don&#8217;t even really matter. Even if they actually believe the forced logic that grieving people with profound symptoms won&#8217;t get necessary treatment [eg antidepressants], they should be able to see that risk\/benefit considerations are prohibitive. Add to that &#8211; nobody wants them to do this other than a few people on the DSM-5 Mood Disorders Work Group. I was actually glad to see that Dr. Frances retains a level-headed approach to the problem:<\/div>\n<blockquote>\n<div align=\"center\"><a target=\"_blank\" href=\"http:\/\/www.psychologytoday.com\/blog\/dsm5-in-distress\/201301\/last-plea-dsm-5-save-grief-the-drug-companies\">Last Plea to DSM 5: Save Grief From the  Drug Companies<\/a><\/div>\n<div align=\"center\"><strong><font color=\"#0066ff\">Psychology Today: DSM5 in Distress<\/font><\/strong>  <br \/>             by Allen Frances, M.D.  <br \/>          January 3, 2013<\/div>\n<p align=\"justify\"><sup><strong>In my list of the 10 worst things about DSM 5, its decision to confuse normal grief with clinical depression earned a very high ranking at second place. DSM 5 will go to press at the end of January. The American Psychiatric  Association has just four more weeks to reverse this dreadful mistake  that flies in the face of clinical common sense and is unsupported by  the limited available science.<\/strong><\/sup><\/p>\n<p align=\"justify\"><sup><strong>The DSM 5 medicalization of grief  has been opposed by editorials and scientific papers in the major  medical and psychiatric journals, by hundreds of newspapers articles,  and by the 200,000 grievers who viewed a moving blog by Joanne  Cacciatore that went viral. So far, APA has lived in its cocoon &#8211; stubbornly sticking to  its senseless decision, oblivious to the intense opposition both from  the experts in the field and from the many people it will mislabel.  Making grief a mental disorder will be a bonanza for drug companies, but  a disaster for grievers.<\/strong><\/sup><\/p>\n<div align=\"justify\"><sup><strong>The decision is also self destructive  for DSM 5 and further undermines the credibility of APA. Psychiatry  should not be mislabeling the normal. Instead, our field should focus  attention on getting more resources for the treatment of patients with  clear and severe mental disorders- those who are now receiving far too  little care as mental health budgets are slashed. This final plea  to reason comes from the three people who have been most active in  protecting grief from being mislabeled as mental illness.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">Dr. Frances reports on the thoughts of three people with hard-won expertise in the treatment of the bereaved:     <\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>The first is <a target=\"_blank\" href=\"http:\/\/drjoanne.blogspot.com\/2012\/12\/the-death-of-sadness-birth-of-mental.html\">Joanne Cacciatore<\/a> &#8211; psychologist, researcher, clinician , bereaved parent, and founder of the MISS Foundation and Center for Loss &amp; Trauma&#8230;:<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong> &quot;It  is simply outrageous that DSM 5 will diagnosis mental disorder in the  normally bereaved as early as two weeks following their loss- thus  encouraging the massive misdiagnosis of grief as Major Depressive  Disorder. Under trained primary care doctors are particularly likely to  confuse grief and depression and to over treat with psychotropic medication.  Drugs are necessary for the severe symptoms of depression in some  individuals, but there is no evidence they are good for expectable  grief. In fact, the research shows that the bereaved are already being  medicated earlier than can be justified.&quot; &quot;We issue an ardent  appeal to DSM 5. Please, do not medicalize normal grief. It is not at  all pathological to have symptoms that closely resemble mild depression  during bereavement. The Bereavement Exclusion is absolutely necessary to protect against the false positive over diagnosis of depression.  Keep it in place. The bereaved are already vulnerable. So, please take  to heart your responsibility to them- &#8216;first do no harm&#8217;.&quot;<\/strong><\/sup><\/div>\n<\/blockquote>\n<blockquote>\n<div align=\"justify\"><sup><strong>The  second email is from <a target=\"_blank\" href=\"http:\/\/www.griefrecoverymethod.com\">Russell Friedman<\/a>: co-founder of The Grief Recovery  Institute Educational Foundation and co-author of &#8216;The Grief Recovery  Handbook&#8217; and &#8216;When Children Grieve&#8217;:<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong> &quot;One  of the very few defenders of the indefensible DSM 5 decision to  pathologize grief is quoted as saying : &#8216;Well-trained clinicians will be  able to make this distinction [between normal grief and depression] and  most have done so without the help of DSM-5 for many years.&#8217;&quot;<\/strong><\/sup><\/div>\n<p>       <\/p>\n<div align=\"justify\"><sup><strong>&quot;This  is far too optimistic an appraisal &#8211; true only for the distinction  between grief and severe depression. Not even the best trained  clinicians can distinguish grief from mild depression. And a totally  untrained and ill-equipped GP, in his 6-8 minute consultation with the  new widow or widower, might as well be blindfolded and throw darts at  targets marked MDE or Normal Grief, while prescribing unnecessary meds  that will bury the griever&rsquo;s feelings- where they will likely fester. In  its zealous attempt never to miss any possible patient, DSM 5 endorses  further loosening of what are already too loose criteria for depression &#8211;  thus mislabeling grief and potentially hurting many millions of  grievers.&quot;<\/strong><\/sup><\/div>\n<\/blockquote>\n<blockquote>\n<div align=\"justify\"><sup><strong>The third email is <a target=\"_blank\" href=\"http:\/\/www.nyu.edu\/socialwork\/our.faculty\/jerome.wakefield.html\">Jerry Wakefield<\/a>, Professor Of Social  Work and Psychiatry at New York University:<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong> &quot;DSM  5 claims that its decision to relabel mild depressive feelings during  grief as clinical depression was based on scientific evidence. This is  simply not true. In fact, the evidence goes strongly against the  decision. For example, two critical features of clinical  depression are that it predicts a higher likelihood of later recurrence  of new depressive episodes and a highly elevated rate of suicide  attempts. Studies show that the depressive feelings during grief that  the DSM 5 is going to relabel clinical depression do not predict higher  rates of either of these problems.<\/strong><\/sup><\/div>\n<p align=\"justify\"><sup><strong>&quot;The scientific literature  documents that on many other important measures as well, such grief is  unlike clinical depression and more like intense normal emotions that  improve on their own with time. Similar normal feelings of  sadness occur in reactions to other losses, such as marital dissolution,  romantic betrayal, job loss, financial trouble, natural disaster, and a  terrible medical diagnosis. Such reactions are currently diagnosed as  psychiatric disorders when in fact studies show they too are often  normal responses. The evidence indicates that DSM 5 should be narrowing  the category of clinical depression, not broadening it.&quot;<\/strong><\/sup><\/p>\n<div align=\"justify\"><sup><strong>&quot;Grieving individuals need and deserve support and frequently consult general physicians seeking help with sleep  or other symptoms. The provision of such help should not be distorted  by a spurious medical diagnosis that is not supported by the scientific  evidence.&quot;<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">And then adds his own commentary:     <\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>Many thanks to all three correspondents for this and  for their previous efforts to save DSM 5 from itself. The need to  preserve Freud&#8217;s valuable distinction between &#8216;Mourning&quot; and  &quot;Melancholia&#8217; seems self evident to everyone except the people  responsible for DSM 5. There was no previous problem in DSM IV  that needed fixing. Grievers who have severe and urgent symptoms-  suicide risk, psychotic symptoms, severe agitation. Inability to  function- have always qualified for the diagnosis of Major Depressive  Disorder; while those having typical symptoms of grief were  appropriately regarded as having a normal, human reaction to a grave  loss. As Dr Wakefield points out, the criteria for mild forms of Major  Depressive Disorder are already too loose when people are experiencing  any kind of loss &#8211; DSM 5 now makes the strange choice of making them  looser.<\/strong><\/sup><\/div>\n<p align=\"justify\"><sup><strong>After 40 years and lots of clinical experience, I can&#8217;t  distinguish at two weeks between the symptoms of normal grief and the  symptoms of mild depression &#8211; and I challenge anyone else to do so. This  is an inherently unreliable distinction. And I know damn well that  primary care doctors can&#8217;t do it in a 7 minute visit. This should have  been the most crucial point in DSM 5 decision making  because primary care docs prescribe 80% of all antidepressants and will  be most likely to misuse the DSM 5 in mislabeling grievers. Drug  companies will probably jump at this golden opportunity to mount a  disease awareness &#8216;educational campaign&#8217; spreading the false DSM 5  gospel that depression can be reliably diagnosed among normal grievers.  And the instinct of primary care docs is always to reach for their  prescription pads or the free samples on the shelf as the quickest way  to get the griever out of the office. Grief is a normal and  inescapable part of the human condition, not to be confused with  psychiatric illness. Let us respect the dignity of mourning and treat it  medically only when it becomes melancholia.<\/strong><\/sup><\/p>\n<div align=\"justify\"><sup><strong>APA needs to  reconsider a really bad decision that will seriously reduce its  credibility and encourage the DSM 5 boycott I am told is now in its  planning stages.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">When I looked at the articles by the Mood Disorder Work Group authors a few days ago [<a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2012\/12\/31\/the-what-is-absurd\/\">the <em>what<\/em> is absurd&hellip;<\/a>], the ten year old article using Wellbutrin to treat grief struck me:<\/div>\n<blockquote>\n<div align=\"center\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11379835\" target=\"_blank\">Bupropion sustained release for bereavement: results of an open trial.<\/a><br \/>                   <sup>by Zisook S, Shuchter SR, Pedrelli P, Sable J, and Deaciuc SC.<\/sup><br \/>                   <strong><font color=\"#200020\">Journal of Clinical Psychiatry<\/font><\/strong>. 2001 62[4]:227-230.<\/div>\n<p>     <\/p>\n<div align=\"justify\"><sup><strong><u><font color=\"#200020\">OBJECTIVE<\/font><\/u>: The present study was conducted to assess whether DSM-IV-defined bereavement responds to bupropion sustained release [SR].<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong><u><font color=\"#200020\">METHOD<\/font><\/u>:  Twenty-two  subjects who had lost their spouses within the previous 6  to 8 weeks  and who met DSM-IV symptomatic\/functional criteria for a  major  depressive episode were evaluated. Subjects completed the  Hamilton  Rating Scale for Depression [HAM-D], the Clinical Global  Impressions  scale, the Texas Revised Inventory of Grief, and the  Inventory of  Complicated Grief at baseline and follow-up. Subjects were  treated with  bupropion SR, 150 to 300 mg\/day, for 8 weeks.<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong><u><font color=\"#200020\">RESULTS<\/font><\/u>: Improvement  was noted in both depression and grief intensity. For the  intent-to-treat group. 59% experienced a reduction of <u>&gt;<\/u>  50% on  HAM-D scores. The correlations between changes in the HAM-D  scores and  the grief scale scores were high, ranging from 0.61 [p =  .006] to 0.44  [p = .054].<\/strong><\/sup><\/div>\n<div align=\"justify\"><sup><strong><u><font color=\"#200020\">CONCLUSION<\/font><\/u>:  Major depressive symptoms  occurring shortly after the loss of a loved  one [i.e., bereavement]  appear to respond to bupropion SR. Treatment of  these symptoms does not  intensify grief; rather, improvement in  depression is associated with  decreases in grief intensity. The results  of this study challenge  prevailing clinical wisdom that DSM-IV-defined  bereavement should not be  treated. Larger, placebo-controlled studies  are indicated.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">That study had no control group so it really shouldn&#8217;t even be in the mix, but there was something else, &quot;<em>Twenty-two  subjects who had lost their spouses <strong><font color=\"#200020\">within the previous 6  to 8 weeks<\/font><\/strong>  and who met DSM-IV symptomatic\/functional criteria for a  major  depressive episode were evaluated.<\/em>&quot; Even they waited a considerably greater time than they&#8217;re suggesting in their appeasment plans for the DSM-5. <\/div>\n<p> <\/p>\n<div align=\"justify\">Another thing that I thought as I read through all those articles was:<\/div>\n<ul>\n<div align=\"justify\"><sup><strong>&quot;The fact that they interpreted their results as meaning the Bereavement  Exclusion needs to be abolished is a telling, and very discouraging. To  me it means that they have come to see the DSM-III, DSM-IV, and now  DSM-5 definition of Major Depressive Disorder as a sacrosanct entity  unto itself rather that just a list made at some point in history for  reasons having to do with an anachronistic political squabble within  psychiatry. They&rsquo;ve confused the signifier with the signified&#8230;&quot;<\/strong><\/sup><\/div>\n<\/ul>\n<div align=\"justify\">I still feel surprised that they can be this far off the mark and apparently not know it. They&#8217;re missing the boat about Grief, plain and simple. They&#8217;re off the mark about the motives of Dr. Frances who is trying his best to keep them from jumping into the deep end of the pool without knowing how to swim. And they&#8217;re assuming a right to make an arbitrary and counter-intuitive change with neither scientific evidence nor credible argument. If they persist and send the DSM-5 to the printer with the Bereavement Exclusion removed, they are as much as admitting that it is no longer the <strong><font color=\"#200020\">Diagnostic and Statistical Manual<\/font><\/strong> <strong><font color=\"#200020\">of Mental Disorders<\/font><\/strong>. It&#8217;s something else, maybe a <strong><font color=\"#200020\">Manual of Psychiatric Opinion &#8211; APA style<\/font><\/strong>, and they&#8217;d best make a drastic cut in the number of copies they order, because they are claiming an authority that they haven&#8217;t earned. They&#8217;ve spent a lot of time and money on this revision, and they&#8217;re about to throw it all away for no apparent reason. The vote is in and counted&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>I had a long and complicated look at Major Depressive Disorder, the Bereavement Exclusion, and the proposal to remove it in the DSM-5 a few days ago [the what is absurd&hellip;]. I realized how angry I am that they want to take out the Bereavement Exclusion yet neglect their real task &#8211; revising the whole [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-31667","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=31667"}],"version-history":[{"count":15,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31667\/revisions"}],"predecessor-version":[{"id":31677,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31667\/revisions\/31677"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=31667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=31667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=31667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}