{"id":31728,"date":"2013-01-05T22:27:28","date_gmt":"2013-01-06T03:27:28","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=31728"},"modified":"2013-01-05T22:32:21","modified_gmt":"2013-01-06T03:32:21","slug":"unchanged","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2013\/01\/05\/unchanged\/","title":{"rendered":"unchanged?&#8230;"},"content":{"rendered":"<div>Just another small point about the Field Trial editorial, this part of the editorial didn&#8217;t make any sense to me:<\/div>\n<blockquote>\n<div align=\"center\"><a href=\"http:\/\/ajp.psychiatryonline.org\/article.aspx?articleID=1555604\" target=\"_blank\" title=\"[full text on-line]\">The Initial Field Trials of DSM-5: New Blooms  and Old Thorns<\/a><br \/>               <sup>by Robert Freedman, David A.  Lewis, Robert Michels, Daniel S. Pine, Susan K. Schultz, Carol A. Tamminga, Glen O. Gabbard, Susan Shur-Fen Gau, Daniel C. Javitt, Maria A. Oquendo, Patrick E. Shrout, Eduard Vieta, and Joel Yager <\/sup><br \/>               <strong><font color=\"#004400\">American Journal of  Psychiatry<\/font><\/strong> 2013 170:1-5.<\/div>\n<p>     <\/p>\n<div align=\"justify\"><sup><strong>The questionable reliability of major depressive disorder, <font color=\"#660033\">unchanged  from DSM-IV<\/font>, is obviously a problem. Major depressive disorder has  always been problematic because its criteria encompass a wide range of  illness, from gravely disabled melancholic patients to many individuals  in the general population who do not seek treatment. Although symptom  severity on the Hamilton Depression Rating Scale distinguishes those  patients who respond more specifically to pharmacotherapy, the DSM-IV  criteria do not capture that distinction.  A second problem not resolved by the DSM-IV criteria is the common  co-occurrence of anxiety, which markedly diminishes the effects of  antidepressant treatment.  The DSM-5 work group decided not to change the criteria for major  depressive disorder from DSM-IV and instead created other diagnoses for  the mixture between anxiety and depression. However, these efforts did  not improve the poor reliability of DSM-IV depression; &ldquo;mixed anxiety  and depression&rdquo; has a kappa of 0&#8230;<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">The comment about the reliability [kappa] of major depressive disorder being &quot;<strong><font color=\"#660033\">unchanged  from DSM-IV<\/font><\/strong>&quot; didn&#8217;t fit with my information. The DSM-5 Field Trials for MDD reported kappa = 0.25 with 95% CL [0.13-0.36]. I just happen to own a used copy of the DSM-IV Sourcebook Volume 4:<\/div>\n<div align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"119\" vspace=\"5\" height=\"179\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/dsm-iv-source.gif\" \/><\/div>\n<div align=\"justify\">I bought it for the following paragraph alone. I wanted to see if the DSM-5 Standards had been redefined as Dr. Frances reported in his blog. This is what the DSM-IV Sourcebook said:<\/div>\n<div align=\"center\"><img decoding=\"async\" width=\"482\" vspace=\"5\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/dsm-iv-kappa.gif\" \/><\/div>\n<div align=\"justify\">Dr. Frances spoke the truth. And this was the standard reportedly used by the DSM-5 Task Force:<\/div>\n<blockquote>\n<div align=\"center\"><strong><font color=\"#200020\">DSM-5: How Reliable Is Reliable Enough?<\/font><\/strong><br \/>                      <sup>by Helena  Chmura Kraemer, David J. Kupfer, Diana E. Clarke,  William E. Narrow, and Darrel A. Regier<\/sup><br \/>                      <strong><font color=\"#004400\">American Journal of Psychiatry<\/font><\/strong> 2012 169:13-15.<\/div>\n<p>  <\/p>\n<div align=\"justify\"><sup><strong>&#8230; to see a &kappa;<sub>I<\/sub> for a DSM-5 diagnosis above 0.8 would be almost miraculous; to see &kappa;<sub>I<\/sub> between 0.6 and 0.8 would be cause for celebration. A realistic goal is &kappa;<sub>I<\/sub> between 0.4 and 0.6, while &kappa;<sub>I <\/sub>between  0.2 and 0.4 would be acceptable.<br \/>  <\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">So, I opened the book again to the chapter on the DSM-IV Field Trials for major depressive disorder that showed a table with the multiple comparisons they did for reliability [kappa]:<\/div>\n<div align=\"center\"><img decoding=\"async\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/dsm-iv-mdd.gif\" \/><\/div>\n<div align=\"justify\">I don&#8217;t see anything like a kappa = 0.25, no matter what they compared with what. So I have no clue what &quot;<strong><font color=\"#660033\">unchanged  from DSM-IV<\/font><\/strong>&quot; means&#8230;<\/div>\n<hr size=\"1\" \/>\n<div align=\"justify\"><sup><strong>By the way, if anyone&#8217;s looking for a DSM-IV Sourcebook Volume 4, I&#8217;ve got one I&#8217;ll let go of for a song&#8230;<\/strong><\/sup><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Just another small point about the Field Trial editorial, this part of the editorial didn&#8217;t make any sense to me: The Initial Field Trials of DSM-5: New Blooms and Old Thorns by Robert Freedman, David A. Lewis, Robert Michels, Daniel S. Pine, Susan K. Schultz, Carol A. Tamminga, Glen O. Gabbard, Susan Shur-Fen Gau, Daniel [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-31728","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=31728"}],"version-history":[{"count":10,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31728\/revisions"}],"predecessor-version":[{"id":31738,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/31728\/revisions\/31738"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=31728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=31728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=31728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}