{"id":33893,"date":"2013-03-07T13:52:30","date_gmt":"2013-03-07T18:52:30","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=33893"},"modified":"2013-03-07T13:58:46","modified_gmt":"2013-03-07T18:58:46","slug":"an-anniversary-2","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2013\/03\/07\/an-anniversary-2\/","title":{"rendered":"an anniversary&#8230;"},"content":{"rendered":"\n<p align=\"center\"><img decoding=\"async\" vspace=\"7\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/jaspers-2.gif\" \/><br \/>               <sup>Kraepelin [1856-1926]&nbsp; Jaspers [1883-1969]&nbsp;&nbsp; Freud [1856-1939]<\/sup><\/p>\n<div align=\"justify\">If you know of <a target=\"_blank\" href=\"http:\/\/en.wikipedia.org\/wiki\/Karl_Jaspers\">Karl Jaspers<\/a>, you were probably one of those philosophy majors who read his commentaries on Kierkegaard and Nietzsche, knowing him as an important  mid-20th century German philosopher. But he was, in fact, a psychiatrist who wrote a classic psychiatric text in 1913 at age thirty, before turning to philosophy some ten years later. I was pointed to this month&#8217;s <em>World Psychiatry<\/em> to look at another article altogether, but I was captured by this editorial marking the hundred year anniversary of Karl Jaspers&#8217; <em>Allgemeine Psychopathologie<\/em> [General Psychopathology] which is as timely today as the day it was written:<\/div>\n<blockquote>\n<div align=\"center\"><strong><font color=\"#200020\">Mental disorders as &ldquo;brain diseases&rdquo; and Jaspers&rsquo; legacy<\/font><\/strong><br \/>                     <sup>by MARIO MAJ <\/sup><br \/>                     <strong><font color=\"#200020\">World Psychiatry<\/font><\/strong>. 2013 12:1-3.<\/div>\n<p>                      <\/p>\n<div align=\"justify\"><sup><strong><img decoding=\"async\" vspace=\"2\" hspace=\"4\" height=\"125\" border=\"1\" align=\"right\" src=\"http:\/\/1boringoldman.com\/images\/jaspers.jpg\" \/>This year we celebrate the 100th anniversary of the publication of the first edition of Karl Jaspers&rsquo; General Psychopathology, and some authors have already noticed significant analogies between the historical moment in which that classical text appeared and the present one. The most striking analogy is that nowadays, exactly like one century ago, the enthusiasm brought about by a period of exceptional progress of research in neurosciences is being followed by some disillusionment, due to the limited relevance of that progress to the elucidation of the pathophysiology of mental disorders. To this disillusionment, the psychiatric field is now reacting in a way that resonates in several respects with Jaspers&rsquo; analysis, making a revisitation of his General Psychopathology extremely useful&#8230;<\/strong><\/sup><\/div>\n<p>            <\/p>\n<div align=\"justify\"><sup><strong><img decoding=\"async\" hspace=\"4\" height=\"155\" border=\"0\" align=\"left\" src=\"http:\/\/1boringoldman.com\/images\/jaspers.gif\" \/>In line with Jaspers&rsquo; analysis is first of all the current acknowledgment of the limitations of the scientific paradigm of 19th century medicine [identifying signs and symptoms, constructing syndromes, taking course into account, and then looking for biological processes that explain the syndromes], when applied to psychiatry. That paradigm seemed to work in the case of general paresis of the insane. However, as Jaspers notices, that disease was not an appropriate &ldquo;model for clinical psychiatric research&rdquo;. In fact, the symptomatic psychoses occurring in general paresis were &ldquo;in no way different from other psychoses associated with brain disease, neither in the psychological symptoms nor in the sequence of psychic phenomena throughout the illness&rdquo;. Apart from general paresis, Jaspers argues, &ldquo;there has been no fulfillment of the hope that clinical observation of psychic phenomena, of the life-history and of the outcome might yield characteristic groupings which would subsequently be confirmed in the cerebral findings&rdquo;. &ldquo;The idea of the disease-entity is in truth an idea in Kant&rsquo;s sense of the world&rdquo;. Even in the cases of schizophrenia and manic-depressive illness, &ldquo;one is always confined to types&rdquo;, that is, &ldquo;fictitious constructs which in reality have fluid boundaries&rdquo;&#8230;.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">When I began in psychiatry, that&#8217;s what I thought and still think. Without really realizing it was happening, I had become more interested in the sick people than the medical diseases that made them sick, and had been drawn to learn more. If I had thought that the mental illnesses were brain diseases, I would&#8217;ve happily stayed in Internal Medicine. When I got to psychiatry and encountered the major psychiatric illnesses like Schizophrenia and Melancholia, I will admit that even in those dire conditions [which I assume are biological], I remained more interested in the afflicted than their afflictions. It is refreshing to read Jaspers&#8217; version of those same kind of thoughts after a third of a century of hearing endlessly from an overly-medicalized psychiatry.<\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>In this context, the basic heterogeneity of mental disorders should not be overlooked. &ldquo;Contemporary neo-Kraepelinian American psychiatry &#8230; practices as if there were biological commitments to over 300 DSM-defined entities, while the biological model may apply only to a few mental disorders, for instance, &ldquo;schizophrenia, manic-depressive illness, melancholic depression and obsessive-compulsive disorder&rdquo;. These recent statements resonate with Jaspers&rsquo; classification of mental disorders into three groups &mdash; cerebral illnesses [such as Alzheimer&rsquo;s disease], major psychoses [such as schizophrenia and manic-depressive illness], and personality disorders [including neurotic syndromes and abnormal personalities] &mdash; which are &ldquo;essentially different from each other&rdquo; and not equally amenable to biological research [those of the third group may just represent &ldquo;variations of human nature&rdquo;].<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">&#8230; <em>the biological model may apply only to a few mental disorders, for  instance, &ldquo;schizophrenia, manic-depressive illness, melancholic  depression and obsessive-compulsive disorder.&rdquo;<\/em> Those are the very conditions that I think of as the psychiatric <em>diseases<\/em> &#8211; biological? yes. pathophysiology? unknown so far.<\/div>\n<div align=\"center\"><img decoding=\"async\" height=\"150\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/jaspers-1.gif\" \/><\/div>\n<div align=\"justify\">I had never read about Jaspers&#8217; psychiatrist days. I don&#8217;t think I even knew he was a psychiatrist. My main recollection of him was as an existentialist that was somewhat intelligible to the likes of me [one of the few]. But reading this, I think his change of career was psychiatry&#8217;s loss. This is an eminently sensible way to conceptualize mental disorders. This larger circle [personality disorders &#8211; <em>&ldquo;variations of human nature&rdquo;<\/em>] with its heterogeneity and indistinct borders has been concretely partitioned these days into <em>target symptoms<\/em> for a hungry pharmaceutical industry, and has recently escaped an attempt at inclusion under the biological umbrella without solid evidence that it belongs there [DSM-5]. Our modern classifications are so complicated by disciplines, economics, industries, ideologies, institutions, and the like, it&#8217;s refreshing to read the thoughts of someone who was outside the monotonous contemporary dialogs and primarily thinking about the mentally ill people.<\/div>\n<blockquote>\n<div align=\"justify\"><sup><strong>Finally, Jaspers&rsquo; emphasis on patients&rsquo; &ldquo;working through the illness&rdquo;, of which the &ldquo;laborious development of a delusional system out of delusional experiences&rdquo; is the best example, resonates with the contemporary notion that &ldquo;the role of the person in mental disorder is not peripheral, merely as a passive victim of a disease to be fixed by medicine&rdquo;, and that person&ndash;disorder interactions are crucial in the shaping of psychopathological symptoms. So, not only patients&rsquo; primary subjective experiences should be a major focus of psychopathological and neuroscientific enquiry, but patients&rsquo; &ldquo;attitude to their illness&rdquo; can represent an important target for both research and intervention. These are just a few examples of basic philosophical issues in psychiatry that are as relevant today as they were one century ago. They suggest that, although our diagnostic systems may be devised as &ldquo;atheoretical&rdquo;, contemporary psychiatry does need a guiding philosophy. &ldquo;If anyone thinks he can exclude philosophy and leave it aside as useless, he will eventually be defeated by it in some obscure form or other&rdquo;. This is one of the reasons why a revisitation of Jaspers&rsquo; General Psychopathology, on the occasion of the 100th anniversary of the publication of its first edition, may represent a useful exercise for everyone involved in psychiatric research and practice.<\/strong><\/sup><\/div>\n<\/blockquote>\n<div align=\"justify\">As a philosopher, Jaspers, like many of his contemporaries, worried about the human encounter with technology, science, and collective institutions &#8211; seeing them as barriers to personal freedom. He urged a <em>Transcendence<\/em> of the limits of rational objectivism to achieve what he called <em>Existenz<\/em> &#8211; an authentic subjectivity. Like so many, his career was suspended during the Nazi era when he and his Jewish wife spent the war in fear of the very kinds of technology and ideology he had written about. After the war, he resumed teaching, writing about the German responsibility for the atrocities of the Third Reich [<em>Die Shuldfrage<\/em>]. Where Jaspers&#8217; <em>Allgemeine Psychopathologie<\/em> criticized Kraepelin for an <em>over<\/em>-reliance on a medical model, he would later criticize Freud for <em>over<\/em>-generalizing about human experience from a limited field of observation.<\/div>\n<p>     <\/p>\n<div align=\"justify\">Stepping back from the loftier interface between science and philosophy that are such a pleasure for an old man to think about, Jaspers the psychiatrist, the philosopher, and the person presaged and lived through many of the issues that plague the psychiatry of 2013. Author Mario Maj points to the obvious:<\/div>\n<ul>\n<div align=\"justify\"><sup><strong>&quot;The most striking analogy is that nowadays, exactly like one century  ago, the enthusiasm brought about by a period of exceptional progress of  research in neurosciences is being followed by some disillusionment,  due to the limited relevance of that progress to the elucidation of the  pathophysiology of mental disorders.&quot;<\/strong><\/sup><\/div>\n<\/ul>\n<div align=\"justify\">I agree with Maj, but see that more as an expected phase in the exhaustion of a scientific paradigm &#8211; the swinging of a pendulum. But what I do ponder is how this particular <em>scientific<\/em> revolution in psychiatry in 1980 gave rise to such a widespread level of corruption in both individuals and institutions. Jaspers turned to philosophy after World War I, warning about existential despair and the threats to individuals in the face of ideology, scientific technology, and political institutions. He then had to live through the worst perversion of those very things the world has ever known, Hitler&#8217;s Germany, kept in place by a powerful German industrial complex. One must always be careful about analogizing anything to the Nazis, such an easy place for exaggeration, but the massive intrusion of industry into the field of psychiatry does touch a similar point. Much of the psychiatric literature that followed our <em>scientific revolution<\/em> and open commitment to <em>evidence-based medicine<\/em> will stand in history as a testament to a perversion of those very principles in the service of commercial goals. Jaspers felt that all of German Society was culpable for the Nazi atrocities. I think he would similarly hold the whole of psychiatry responsible for the many misadventures of the last thirty years. And back to Jaspers the psychiatrist. He saw three different versions of the psychiatric disorders:<\/div>\n<ul>\n<div align=\"justify\"><sup><strong>&#8230; Jaspers&rsquo; classification of mental disorders into three groups &mdash;  cerebral illnesses [such as Alzheimer&rsquo;s disease], major psychoses [such  as schizophrenia and manic-depressive illness], and personality  disorders [including neurotic syndromes and abnormal personalities] &mdash;  which are &ldquo;essentially different from each other&rdquo; and not equally  amenable to biological research [those of the third group may just  represent &ldquo;variations of human nature&rdquo;].<\/strong><\/sup><\/div>\n<\/ul>\n<div align=\"justify\">I don&#8217;t doubt that <em>a few<\/em> of the inhabitants of Jaspers&#8217; greater circle [personality disorders &#8211; <em>&ldquo;variations of human nature&rdquo;<\/em>] may turn out to have <em>some<\/em> biologic aspect to their illnesses, and that <em>some<\/em> may be genuinely helped by mood altering drugs. But the recurrent rhetoric of organized and academic psychiatry that the great hope for these people is in biological research and pharmacologic treatment strikes me as delusional [a delusion = a fixed, false belief]. What Jaspers said a century ago remains true:<\/div>\n<ul>\n<div align=\"justify\"><sup><strong>&#8230; &ldquo;there has been no fulfillment of the hope that clinical observation  of psychic phenomena, of the life-history and of the outcome might yield  characteristic groupings which would subsequently be confirmed in the  cerebral findings&rdquo;. &ldquo;The idea of the disease-entity is in truth an idea  in Kant&rsquo;s sense of the world&rdquo;.<\/strong><\/sup><\/div>\n<\/ul>\n<div align=\"justify\">The only difference is that we&#8217;ve amassed a lot more <em>cerebral findings<\/em> these days. And for that matter, we&#8217;ve made up a whole lot more <em>disease entities<\/em>&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Kraepelin [1856-1926]&nbsp; Jaspers [1883-1969]&nbsp;&nbsp; Freud [1856-1939] If you know of Karl Jaspers, you were probably one of those philosophy majors who read his commentaries on Kierkegaard and Nietzsche, knowing him as an important mid-20th century German philosopher. But he was, in fact, a psychiatrist who wrote a classic psychiatric text in 1913 at age thirty, [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-33893","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/33893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=33893"}],"version-history":[{"count":61,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/33893\/revisions"}],"predecessor-version":[{"id":44870,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/33893\/revisions\/44870"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=33893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=33893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=33893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}