{"id":4530,"date":"2010-12-05T10:59:32","date_gmt":"2010-12-05T15:59:32","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=4530"},"modified":"2010-12-05T18:11:23","modified_gmt":"2010-12-05T23:11:23","slug":"a-worthy-cause","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2010\/12\/05\/a-worthy-cause\/","title":{"rendered":"a worthy cause&#8230;"},"content":{"rendered":"<br \/>\n<blockquote>\n<div align=\"center\"><strong><a href=\"http:\/\/blogs.wsj.com\/health\/2009\/08\/20\/caspper-glaxosmithklines-friendly-ghostwriting-program\/\" target=\"_blank\">CASPPER, GlaxoSmithKline&rsquo;s Friendly Ghostwriting Program<\/a><br \/>                 Wall Street Journal <\/strong><br \/>                 By Jacob Goldstein<br \/>                 <strong><font color=\"#990000\">August 20, 2009 <\/font><\/strong><\/div>\n<p align=\"justify\"><img decoding=\"async\" width=\"60\" hspace=\"5\" border=\"1\" align=\"right\" src=\"http:\/\/online.wsj.com\/media\/casper_CV_20090820124118.jpg\" \/>Drug  makers have been taking heat for a while now over ghostwritten articles  in medical journals. Basically, there have been instances where drug  companies went out and found doctors willing to put their names on  articles that the company paid someone else to write or make significant  contributions to.<\/p>\n<div align=\"justify\">So it isn&rsquo;t surprising to learn from the <strong><a target=\"_blank\" href=\"http:\/\/www.latimes.com\/business\/nationworld\/wire\/sns-ap-us-glaxosmithkline-ghostwriting,0,7584289.story\">Associated Press<\/a><\/strong>  that GlaxoSmithKline used this sort of program several years back to  generate articles favorable to its antidepressant Paxil. But the company  gave the program a name too clever for us to pass up: CASPPER. Think of  it as your own friendly ghostwriter&#8230;<\/div>\n<\/blockquote>\n<div align=\"justify\">It&#8217;s a little hard to understand why the doctors exposed for ghost-writing in the recent <a href=\"http:\/\/www.pogo.org\/pogo-files\/letters\/public-health\/ph-iis-20101129.html\" target=\"_blank\"><strong>POGO letter<\/strong><\/a> are even mounting denials. The campaign for <strong>GSK<\/strong>&#8216;s drug, <strong>Paxil<\/strong>, involving ghost-written pro-Paxil medical literature is already common knowledge, and has been for a over a year.                  <\/div>\n<ul>\n<div>&bull; <strong><a target=\"_blank\" href=\"http:\/\/www.boston.com\/news\/nation\/articles\/2009\/08\/20\/glaxosmithkline_used_ghostwriting_to_promote_paxil\/\">Glaxo used ghostwriting to promote Paxil<\/a><br \/>                          <em>Offered to help doctors publish articles on drug<\/em><br \/>                          Boston.com [Associated Press] <\/strong><br \/>                          By Matthew Perrone<br \/>                          August 20, <strong><font color=\"#990000\">2009<\/font><\/strong><\/div>\n<div>&bull; <strong><a target=\"_blank\" href=\"http:\/\/pubrecord.org\/law\/7102\/ghostbusting-paxil-birth-defect\/\">Ghostbusting In Paxil Birth Defect Litigation<\/a><\/strong><br \/>                            <strong>  The Public Record<\/strong><br \/>                               By  Evelyn Pringle<br \/>                              March 3rd, <strong><font color=\"#990000\">2010<\/font><\/strong><\/div>\n<\/ul>\n<div align=\"justify\"><strong><font color=\"#200020\">Evelyn Pringle<\/font><\/strong>&#8216;s article chronicles the trial where much of this information became available &#8211; a successful suit against <strong>GlaxoSmithKline<\/strong> by the family of a child born with a heart defect linked to the drug. <strong>Dr. David Healy<\/strong>, a prominent British Psychopharmacologist, testified about the ghost-writing process at GSK &#8211; naming names and backed up by incriminating subpoenaed documents from the company. In that trial, Dr. Healy laid out how the makers of the drug [<strong>GlaxoSmithKline<\/strong>] marketed it through physicians &#8211; speaking and writing as experts &#8211; who promoted Paxil while minimizing its adverse and sometimes dangerous side effects. He pointed specifically to the marketing firm <strong>Scientific Therapeutic Information<\/strong> [STI] as the ghostwriters in this campaign. He named <strong>Dr. Charles Nemeroff<\/strong>, <strong>Dr. Zach Stowe<\/strong>, and <strong>Dr. Jeffry Newport<\/strong> [of <strong>Emory University Medical School, Department of Psychiatry<\/strong>] as figuring prominently in GSK&#8217;s marketing scheme. Dr. Healy has a personal story of his own about the interference of Pharma in academic medicine. If you don&#8217;t know the story, here&#8217;s a start:          <\/div>\n<ul><img decoding=\"async\" hspace=\"4\" height=\"120\" border=\"1\" align=\"right\" src=\"http:\/\/www.harvardsquarelibrary.org\/HarvardPressBooks\/history_images\/science\/healy.jpg\" alt=\"Dr. David Healy\" title=\"Dr. David Healy\" \/><\/p>\n<div align=\"justify\">&bull; <a href=\"http:\/\/en.wikipedia.org\/wiki\/David_Healy_%28psychiatrist%29\" target=\"_blank\"><strong>David Healy [Psychiatrist]<\/strong><\/a><br \/>            Wikipedia<br \/>      [on-line encyclopedia]       <\/div>\n<div align=\"justify\">&bull; <a href=\"http:\/\/www.pharmapolitics.com\/index.html\" target=\"_blank\"><strong>The David Healy Affair<\/strong><\/a><br \/>              by Bruce Charlton<br \/>              October 2001<\/div>\n<div>&bull; <strong><a href=\"http:\/\/www.healyprozac.com\/default.htm\" target=\"_blank\">Let Them Eat Prozac<\/a><\/strong><br \/>           by David Healy<br \/>      [personal website]          <\/div>\n<\/ul>\n<div align=\"justify\">Like Dr. Healy, I have some personal reasons for being upset about all of this. In 1974, I changed careers from Internal Medicine to Psychiatry and Psychoanalysis because of an interest in the mind, and I never looked back. I was in academic medicine at Emory University after retraining. In the early 1980&#8217;s, a new Chairman arrived, and it was clear that my interests were not compatible with the wave of Biological Psychiatry that was sweeping the specialty, and I left for private practice, continuing to teach in the Psychoanalytic Institute, but no longer involved with the Psychiatry Department. At that time, I wasn&#8217;t bitter and enjoyed my private practice. A few years later, Dr. Nemeroff became Chairman. I had little to no contact with him, but heard plenty. During the decade that followed, Psychiatry changed so much I hardly recognized it. The journals were filled with drug research and meetings became monotonous and boring.<\/div>\n<p align=\"justify\">I learned about the new drugs, and found that the SSRI&#8217;s were effective in controlling depressive and obsessive compulsive symptoms in certain cases, and so I prescribed them, but my main work was as a psychotherapist and psychoanalyst. I personally thought that the &quot;Biological Wave&quot; was something of a fad that would pass in time &#8211; finding its appropriate place. But then I began to realize, along with lots of other colleagues, that the &quot;Biological Wave&quot; was more than a fad, it had a <u>motor<\/u> &#8211; the Pharmaceutical Industry looking for profit. I resented the intrusion of Drug Companies into the practice of Psychiatry and into academic medicine &#8211; the place where practitioners looked for guidance. As time went on, I further learned that the intrusion had reached <u>criminal<\/u> proportions with university physicians in on the the game. That is absolutely infuriating! And a lot of it was centered at my University [Emory], in my town [Atlanta, Georgia], where I practiced &#8211; so I&#8217;m hardly unbiased in this matter. That is my own conflict of interest statement <em>in toto<\/em>.<\/p>\n<p align=\"justify\">The more I read these stories, the more it just seems like a racket, the stuff of flim-flam men and bilko artists. The newer drugs are real &#8211; they aren&#8217;t snake oil or magic bracelets. But they&#8217;re certainly not all there is to treating mental illness. And they are potentially dangerous. We physicians have a covenant with our patients to do no harm in our efforts to help them. And these distortions and manipulations of scientific information directly impede our ability to keep that bargain. It&#8217;s a practical matter. There was a time when books like Nemeroff and Schatzberg&#8217;s <strong><font color=\"#200020\">Recognition and Treatment of Psychiatric Disorders: A Psychopharmacology Handbook for Primary Care<\/font><\/strong> would have kept us abreast of advances and dangers of newer medications. But not so much any more. If that book had said &quot;Commissioned by the makers of Paxil,&quot; I would&#8217;ve known how to read it [or not read it]. But it didn&#8217;t say that. This kind of thing has become way too common and made us appropriately suspicious of our own literature. Industry financed ghost-writing has regularly found its way into our best journals. <\/p>\n<div align=\"justify\">When the <a href=\"http:\/\/www.pogo.org\/pogo-files\/letters\/public-health\/ph-iis-20101129.html\" target=\"_blank\"><strong>POGO letter<\/strong><\/a> came out, the Dean of the Miller School of Medicine in Miami, Dr. Pascal Goldschmidt, defended Drs. Nemeroff and Schatzberg <a href=\"http:\/\/www.miamiherald.com\/2010\/12\/02\/1953955\/um-prof-accused-of-ghostwriting.html\" target=\"_blank\"><strong>saying<\/strong><\/a>:<\/div>\n<blockquote>\n<div align=\"justify\">&quot;It  is unfortunate that two individuals who have contributed so much to  the  medical discipline of psychiatry, Drs. Charles Nemeroff and Alan   Schatzberg, and to the health of so many patients with dreadful   psychiatric illnesses here in the U.S. and beyond, are exposed to such   an unreliable and unfounded challenge to their reputation.&rdquo;<\/div>\n<\/blockquote>\n<div align=\"justify\">Well Goldschmidt&#8217;s defense is &quot;unreliable and unfounded.&quot; I would have a very different take on the &quot;contributions&quot; of Drs. Nemeroff and Schatzberg. The evidence is mounting daily that there has been something very rotten in the state of academic Psychiatry for a very long time &#8211; at Emory, at Stanford, at Yale, at Penn, at Brown, in Miami &#8211; and it&#8217;s high time it comes to an end. Biological Psychiatry is actually too important to the practice of medicine and Psychiatry to leave in the hands of compromised academicians, ghost-writers, and Pharmaceutical Marketing departments. So I find myself falling into the ranks of people who stalk this topic &#8211; hoping to spread the alarm. <\/div>\n<ul>\n<div>&bull; <strong><a href=\"http:\/\/www.nytimes.com\/2010\/11\/30\/business\/30drug.html\" target=\"_blank\">Drug Maker Wrote Book Under 2 Doctors&rsquo; Names, Documents Say<\/a> <br \/>             NewYork Times<\/strong><br \/>             By DUFF WILSON<br \/>             November 29, 2010<\/div>\n<div><strong>&bull; <a href=\"http:\/\/www.browndailyherald.com\/letter-faults-brown-for-inaction-on-professor-1.2421259\" target=\"_blank\">Letter faults Brown for inaction on professor<\/a><br \/>                       The Brown Daily Herald<\/strong><br \/>                       By Sarah Mancone<br \/>                       December 3, 2010<\/div>\n<div>&bull; <strong><a href=\"http:\/\/www.stanforddaily.com\/2010\/12\/01\/professor-apa-dispute-ghostwriting-allegation\/\" target=\"_blank\">Professor, APA dispute ghostwriting allegation<\/a><\/strong><br \/>                       <strong>Stanford Daily<\/strong><br \/>                       by Elizabeth Titus<br \/>                       December 4, 2010<\/div>\n<div>&bull; <a href=\"http:\/\/www.yaledailynews.com\/news\/2010\/dec\/03\/med-prof-accused-ghostwriting\/\" target=\"_blank\"><strong>Med prof accused of ghostwriting<\/strong><\/a><br \/>                    <strong>Yale Daily News<\/strong><br \/>                       By Traci Tillman<br \/>                       December 3, 2010<\/div>\n<div>&bull; <a href=\"http:\/\/www.miamiherald.com\/2010\/12\/02\/1953955\/um-prof-accused-of-ghostwriting.html\" target=\"_blank\"><strong>UM prof accused of submitting ghostwritten textbook<\/strong><\/a><br \/>                 <strong>Miami Herald<\/strong><br \/>                 BY JOHN DORSCHNER<br \/>                 12.02.10<\/div>\n<div>&bull; <strong><a href=\"http:\/\/carlatpsychiatry.blogspot.com\/2010\/12\/nemeroff-and-schatzbergs-textbook.html\" target=\"_blank\">Nemeroff and Schatzberg&rsquo;s &ldquo;Textbook&rdquo; Pushed Paxil<\/a>           <\/strong>           <br \/>           <strong>Carlat Psychiatry blog<\/strong><br \/>                      by Danny Carlat<br \/>                      12\/03\/2010 <\/div>\n<\/ul>\n<div>I&#8217;m fine with being there. It&#8217;s a pretty decent group to be with &#8211; and it&#8217;s certainly a worthy cause&#8230; <\/div>\n","protected":false},"excerpt":{"rendered":"<p>CASPPER, GlaxoSmithKline&rsquo;s Friendly Ghostwriting Program Wall Street Journal By Jacob Goldstein August 20, 2009 Drug makers have been taking heat for a while now over ghostwritten articles in medical journals. Basically, there have been instances where drug companies went out and found doctors willing to put their names on articles that the company paid someone [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-4530","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/4530","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=4530"}],"version-history":[{"count":0,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/4530\/revisions"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=4530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=4530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=4530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}