{"id":48232,"date":"2014-07-20T22:27:24","date_gmt":"2014-07-21T02:27:24","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=48232"},"modified":"2014-07-21T03:26:06","modified_gmt":"2014-07-21T07:26:06","slug":"our-own-eyes","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2014\/07\/20\/our-own-eyes\/","title":{"rendered":"our own eyes&#8230;"},"content":{"rendered":"<div align=\"justify\">In the first post about the <a href=\"http:\/\/www.bmj.com\/content\/348\/bmj.g3596#aff-1\" target=\"_blank\">Lu et al<\/a> study, I mentioned the CDC 1979-2007 suicide data [see <a href=\"http:\/\/1boringoldman.com\/index.php\/2014\/06\/19\/a-madness-to-our-method\/\" target=\"_blank\">a madness to our method&hellip;<\/a>]. But in <a href=\"http:\/\/1boringoldman.com\/index.php\/2014\/07\/15\/its-origin\/\" target=\"_blank\">its origin&hellip;<\/a>, my post had a broken link to the CDC <a href=\"http:\/\/www.cdc.gov\/healthyyouth\/yrbs\/pdf\/us_suicide_trend_yrbs.pdf\" target=\"_blank\">YRBS<\/a> [Youth Risk Behavior Study] in the Rapid Response by <a href=\"http:\/\/www.bmj.com\/content\/348\/bmj.g3596\/rr\/760706\" target=\"_blank\">Barber et al<\/a>. That was an unfortunate omission as it&#8217;s a center ring piece of information. First, here&#8217;s the CDC Suicide data [1979-2007]:<\/div>\n<div align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"430\" vspace=\"7\" height=\"620\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/suicide-79-07-both.gif\" \/><\/div>\n<div align=\"justify\">Here&#8217;s my graphing of the <a href=\"http:\/\/www.cdc.gov\/healthyyouth\/yrbs\/pdf\/us_suicide_trend_yrbs.pdf\" target=\"_blank\">YRBS<\/a> data [1991-2011]:<\/div>\n<div align=\"center\"><img decoding=\"async\" width=\"400\" vspace=\"7\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/yrbs.gif\" \/><\/div>\n<div align=\"justify\">The <a target=\"_blank\" href=\"http:\/\/www.cdc.gov\/healthyyouth\/yrbs\/\">Youth Risk Behavior Surveillance System<\/a> [YRBSS] was&nbsp; actually new for me. It&#8217;s an every other year survey querying dangerous behaviors in kids 16-19. It looks pretty solid to me and I was glad to find it. Take a look. It certainly doesn&#8217;t confirm the findings of <a href=\"http:\/\/www.bmj.com\/content\/348\/bmj.g3596#aff-1\" target=\"_blank\">Lu et al<\/a> [in fact, most things don&#8217;t].<\/div>\n<p align=\"justify\">I honestly don&#8217;t believe that the black box warnings lead to an increase in either suicides or suicide attempts based on scientific grounds, some of which are shown here. But that&#8217;s not what fuels my writing about this. What keeps me writing is what I do believe, not what I don&#8217;t believe. I&#8217;ve seen two completed suicides from SSRIs that I&#8217;m sure about. Thankfully, neither was a patient of mine, but I was privy to enough information to be unquestioning about what happened. I may fill this blog with graphs and population statistics, but as a clinician, I&#8217;m a one-person-at-a-time doctor. And people like me are at a loss because I can&#8217;t or won&#8217;t report why I can say that with such conviction. I also believe in Akathisia of the kind that&#8217;s described in patient reports, books, on RxISK, in blogs etc. I believe it because I&#8217;ve seen it personally in its very loud forms. I can&#8217;t or won&#8217;t report the stories that lead to that conviction either, so I can only say that I have no doubts. I think the black box warning is correct &#8211; the truth:<\/p>\n<p align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"80\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/tads-3.gif\" \/>&nbsp;<\/p>\n<div align=\"justify\">If someone actually did a non-jury rigged study that said that the black box warning is wrong, I wouldn&#8217;t change a single thing in the way I personally do things. David Healy says why best when he talks about getting doctors to &quot;doubt our own eyes.&quot; See Akathisia once, a dramatic change in personality and the aggression that comes with the drug, that then disappears when the drug is withdrawn, and you&#8217;re on alert. See it the second time and that&#8217;s enough for this old man. It might as well be an epidemic. And given the fact that I&#8217;m an infrequent prescriber, that I&#8217;ve seen it often enough makes it real for me. I would bet it&#8217;s even under-reported because the patients stop <em>that drug<\/em> and don&#8217;t go back to see <em>that doctor<\/em>. I&#8217;ve prescribed SSRIs to adolescents and young adults infrequently, and only when I&#8217;ve said my spiel and am comfortable that I and competent others can keep close tabs. I can&#8217;t imagine anything ever changing that. There have been some successes, some failures, and much indifference. So I&#8217;m glad the black box warning slowed down the accelerating rate of prescribing &#8211; even in an HMO. And what I&#8217;ve seen with my eyes trumps epidemiology on large datasets.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>In the first post about the Lu et al study, I mentioned the CDC 1979-2007 suicide data [see a madness to our method&hellip;]. But in its origin&hellip;, my post had a broken link to the CDC YRBS [Youth Risk Behavior Study] in the Rapid Response by Barber et al. That was an unfortunate omission as [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-48232","post","type-post","status-publish","format-standard","hentry","category-politics"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/48232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=48232"}],"version-history":[{"count":15,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/48232\/revisions"}],"predecessor-version":[{"id":48249,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/48232\/revisions\/48249"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=48232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=48232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=48232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}