{"id":53363,"date":"2015-01-21T08:00:05","date_gmt":"2015-01-21T13:00:05","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=53363"},"modified":"2015-01-21T07:58:37","modified_gmt":"2015-01-21T12:58:37","slug":"currently-unsolved-problem","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2015\/01\/21\/currently-unsolved-problem\/","title":{"rendered":"currently unsolved problem&#8230;"},"content":{"rendered":"<br \/>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"http:\/\/psychnews.psychiatryonline.org\/doi\/full\/10.1176\/appi.pn.2015.1b23\">Protecting Academic Psychiatry<\/a><\/div>\n<div align=\"center\" class=\"big\"><strong><font color=\"#200020\">Psychiatric<\/font><font color=\"#990000\">News<\/font><\/strong><\/div>\n<div align=\"center\" class=\"middle\">Paul Summergrad, M.D.<\/div>\n<div align=\"center\" class=\"small\">January 2015 <\/div>\n<div align=\"center\" class=\"middle\">[<a href=\"http:\/\/psychnews.psychiatryonline.org\/doi\/full\/10.1176\/appi.pn.2015.1b23\" target=\"_blank\">full text on-line<\/a>]<\/div>\n<p>                           <\/p>\n<div align=\"center\"><img loading=\"lazy\" decoding=\"async\" height=\"18\" border=\"0\" width=\"66\" src=\"http:\/\/1boringoldman.com\/images\/snip.gif\" \/> <\/div>\n<div align=\"justify\"><img decoding=\"async\" hspace=\"4\" border=\"0\" width=\"120\" align=\"right\" src=\"http:\/\/1boringoldman.com\/images\/apa-7.gif\" \/>It was<strong><font color=\"#990000\"> APA<\/font><\/strong>, along with<strong><font color=\"#990000\"> NIMH <\/font><\/strong>and <strong><font color=\"#990000\">academic psychiatry leadership<\/font><\/strong> in the  latter part of the last century, that <strong><font color=\"#990000\">helped the field to develop to its  current prominence<\/font><\/strong>. It is incumbent upon us to focus our attention on  these issues so that our academic departments remain strong enough to  allow care, new treatments, and education to move forward effectively at  a time when our services have never been more essential or the  potential for fundamental breakthroughs greater.<\/div>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">It is actually unfair of me to snip out this last paragraph from Dr. Summergrad&#8217;s most recent commentary. He&#8217;s the first thoughtful President of the APA in memorable history, and this piece appropriately focuses on a real problem. He lays out the forces involved reasonably well &#8211; until his last paragraphs where, from my vantage, he could&#8217;ve appropriately written&#8230;<\/div>\n<ul>\n<div align=\"justify\" class=\"small\"><em><font color=\"#200020\">It was APA, along with NIMH and academic psychiatry leadership in the  latter part of the last century that lead the field to its  current dilemma.<\/font><\/em><\/div>\n<\/ul>\n<div align=\"justify\" class=\"small\">&#8230; and been more accurate. Certainly, the problems psychiatry faced fifty years ago were daunting and needed to be addressed. The Community Mental Health Movement collided with changes in the collective American attitude towards government involvement in social issues, and it began to wane before it really got started. The psychoanalytic and other psychotherapeutic paradigms had reached a point of exhaustion, yet remained over-represented in the hierarchy of psychiatry. <img decoding=\"async\" hspace=\"4\" border=\"0\" width=\"120\" vspace=\"5\" align=\"right\" src=\"http:\/\/1boringoldman.com\/images\/apa-10.gif\" \/>Long psychotherapies were being billed to medical insurance, a practice that had to change. And there were competitive wars with other mental health specialties. All were problems in need of urgent attention. While there was nothing so wrong with the manifest solution [the APA&#8217;s DSM-III], the method of change [<a href=\"http:\/\/1boringoldman.com\/index.php\/2015\/01\/14\/post-without-an-end\/\" target=\"_blank\">post without an end&hellip;<\/a>], the over-representation of the neoKraepelinian point of view in the background, and the major unmentioned forces [<em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> and <em><strong><font color=\"#366c81\">Managed Care<\/font><\/strong><\/em>] were&nbsp; specters that would haunt psychiatry&#8217;s rise &quot;to its  current prominence&quot; throughout.<\/div>\n<p align=\"justify\" class=\"small\">Reading Dr. Summergrad&#8217;s summary of the problems faced by academic psychiatry today is a <em><font color=\"#200020\"><span class=\"st\">d\u00e9j&agrave; vu<\/span><\/font><\/em> for me &#8211; the quicksand I experienced during the late 1970&#8217;s directing an academic psychiatric training program. Put simply, there was <u>no<\/u> fiscal support in sight. Like the Kalahari Desert on a Discovery Channel special, the verdant plains of a forgotten rainy season had given way to a barren desert with no future promise on the horizon. Whether <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> or <em><strong><font color=\"#366c81\">Managed Care <\/font><\/strong><\/em>was involved in bringing about psychiatry&#8217;s radical changes is immaterial now. But in retrospect, their involvement was an integral part of the story going forward. For <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em>, it portended a large potential psychopharmacology market that was realized beyond its value. And for <em><strong><font color=\"#366c81\">Managed Care<\/font><\/strong><\/em>, that dovetailed into a cost cutting windfall. For practicing psychiatrists, it ultimately became a reimbursable commodity &#8211; as medication managers. And there was a lucrative source of grant funds flowing from <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> &#8216;s good fortune into the embattled academic departments. Research in <em>neuro-anything<\/em> flourished, and the <em><strong><font color=\"#366C81\">Clinical Research Industry<\/font><\/strong><\/em> grew like a weed with academic guest-authorship. The other mental health professions prospered &#8211; providing psychotherapy services with negotiated medical payment.<\/p>\n<p align=\"justify\" class=\"small\"><img decoding=\"async\" hspace=\"4\" border=\"0\" width=\"120\" vspace=\"4\" align=\"left\" src=\"http:\/\/1boringoldman.com\/images\/apa-8.gif\" \/>But now it&#8217;s the dry season again. <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> finally exited the picture three years ago, and the impact of its absence on the economy of academic psychiatry is obviously widely felt. The APA&#8217;s recent failed DSM-5 enterprise also did little for the current state of the specialty. There has been more than a quarter-century-long alliance among academic psychiatry departments, the APA, the NIMH, and the pharmaceutical industry. The practice of psychiatry has come to be centered on outpatient medication management, and many patients have been &quot;left behind.&quot; Add in countless examples of scientific misbehavior and misrepresented authorship in the Clinical Trial literature, particularly with these psychoactive drugs. So while the controversies and some of the players may be similar, this is <em>not the same psychiatry<\/em> that faced that dry season in the 1970s. <\/p>\n<div align=\"justify\" class=\"small\">It&#8217;s the comments in the penultimate paragraph of this essay that actually caught my attention&#8230;            <\/div>\n<blockquote>\n<div align=\"justify\">Also, many in the pharmaceutical and biotechnology industries have shifted from clinical neuroscience research to lower-risk areas with more well-developed genetic targets such as oncology. The net result is that clinical research in departments of psychiatry is systemically challenged. The greatest impact of this change in industry funding is, of course, on patients and families. We are deeply in need of new pharmacotherapies and neurotherapeutics based on specific genetic and neuroscience processes. Highly specific treatments, as the physician and noted author Lewis Thomas reminded us, are not only more effective but generally less toxic. These changes in industry funding, when paired with reductions in the true dollar amount of NIH funding, impact the success and potentially the longer-term viability of academic psychiatry departments. All of this is challenging for the field at what should be a time of enormous promise&#8230;<\/div>\n<\/blockquote>\n<ol>\n<li>\n<div align=\"justify\" class=\"small\"><em><strong><font color=\"#200020\">&quot;We are deeply in need of new pharmacotherapies and neurotherapeutics  based on specific genetic and neuroscience processes&quot;. <\/font><\/strong><\/em>          <\/div>\n<div align=\"justify\" class=\"small\">It&#8217;s in the area of Major Depressive Disorders that the notion of &quot;<em>pharmacotherapies and neurotherapeutics  based on specific genetic and neuroscience processes<\/em>&quot; have been most vigorously pursued. Yet:<\/div>\n<ul><span class=\"small\">         <\/p>\n<li>\n<div align=\"justify\">There is no compelling or replicated evidence that what has been called &quot;Major Depressive Disorders&quot; since the DSM-III Revision is a discrete biological or even <span class=\"small\"> clinical <\/span>condition, much less a disorder with either unitary genetic or neuroscientific roots.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">There is no compelling or replicated evidence that the current psychoactive drugs are disease or disorder specific.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">For these reasons, the NIMH has abandoned the DSM-system altogether and is now chasing other rainbows [the <a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3341647\/\">RDoC<\/a>].<\/div>\n<\/li>\n<li>\n<div align=\"justify\">Studies claiming treatment specificity based on biological markers remain in the range of speculation in spite of intense and expensive efforts otherwise.<\/div>\n<\/li>\n<p>         <\/span><\/ul>\n<div align=\"justify\" class=\"small\">This is the almost ubiquitous future-think &#8211; always looking for something <em>just around the corner<\/em> or <em>down the pike<\/em>, things that never seem to arrive. <\/div>\n<\/li>\n<li>\n<div align=\"justify\" class=\"small\"><em><strong><font color=\"#200020\">&quot;These changes in industry funding, when paired with reductions in the  true dollar amount of NIH funding, impact the success and potentially  the longer-term viability of academic psychiatry departments.&quot;<\/font><\/strong><\/em><\/div>\n<div align=\"justify\" class=\"small\">While the extent of the industry support of academic psychiatry departments has been widely known about for some time, here, <font color=\"#200020\">Dr. Summergrad implies that their very <em><strong>&quot;longer-termed viability&quot;<\/strong><\/em> has depended on that industry support<\/font>. He&#8217;s not talking about gravy, or even dessert, he&#8217;s talking about meat and potatoes here &#8211; basic sustenance. Thinking back, there was no way that the academic department I was a member of in the late 1970s could&#8217;ve survived long term once the government and private hospital support began to dry up. There is essentially no university institutional support or service derived income for post-graduate psychiatric education like there is in other medical specialties.      <\/div>\n<\/li>\n<\/ol>\n<div align=\"justify\" class=\"small\">There are certainly lots of things that suggest that there&#8217;s more than a spiritual tie to <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> among academic psychiatry departments and the APA. It&#8217;s been more like <em>Superglue<\/em>, or maybe a <em>Joint Account<\/em>. <\/div>\n<ul><span class=\"small\">     <\/p>\n<li>\n<div align=\"justify\">The APA bet their whole ship on the DSM-5 making a definitive transition to a biological paradigm with no solid evidence to back up such a shift in tow. Why? It was as bad a bet in 2002 [<a href=\"http:\/\/1boringoldman.com\/wp-admin\/www.unc.edu\/%7Edlinz\/Papers\/A%20Research%20Agenda%20for%20DSM-V.pdf#page=18\" target=\"_blank\">A Research Agenda for DSM-V<\/a>] when they announced their plan as it was in 2011 when they had to call it off [<a href=\"http:\/\/ajp.psychiatryonline.org\/article.aspx?articleID=115987#B6\" target=\"_blank\">Neuroscience, Clinical Evidence, and the Future of Psychiatric Classification in DSM-5<\/a>]. <\/div>\n<\/li>\n<li>\n<div align=\"justify\">When the scientific and financial misbehavior of ranking members of the APA or academic psychiatry have been exposed, we haven&#8217;t heard a peep out of the APA or, for that matter, the NIMH. Why not?   <\/div>\n<\/li>\n<li>\n<div align=\"justify\">The NIMH under Stephen Hyman and Tom Insel have preferentially funded and supported innumerable large scale psychopharmacology trials.Why?<\/div>\n<\/li>\n<li>\n<div align=\"justify\">When it became apparent that <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> was abandoning CNS drug development, there was a collective wail heard from every rafter, followed by an all out [and ongoing] campaign to woo them back. Why so loud? so passionate?   <\/div>\n<\/li>\n<li>\n<div align=\"justify\">The number of highly placed academics who have been willing to sign on to shaky industry funded clinical trials or industry speaker bureaus is&nbsp;<strike> shocking&nbsp;<\/strike> <span class=\"small\">surprising<\/span>. Why so many?   <\/div>\n<\/li>\n<p>     <\/span><\/ul>\n<div align=\"justify\" class=\"small\">I think that I&#8217;ve been naive all along, quantitatively blind. We all know that <em><strong><font color=\"#366c81\">PHARMA <\/font><\/strong><\/em>has been throwing money at academic psychiatrists and their departments since early on in this age of psychopharmacology, but I think I saw it as something like supplemental income, Before I read the phrase, &quot;<font color=\"#990000\"><em><strong>the longer-term viability of academic psychiatry departments<\/strong><\/em><\/font>,&quot; it hadn&#8217;t really occurred to me that the <em><strong><font color=\"#366c81\">PHARMA <\/font><\/strong><\/em>money was <u>the<\/u> vital artery supporting the body of psychiatric education. <em><strong><font color=\"#200020\">The conflict of interest implications of an academic psychiatry that is dependent on industry funding for survival are obvious to anyone that looks &#8211; mind boggling. <\/font><\/strong><\/em><\/div>\n<p align=\"justify\" class=\"small\">I don&#8217;t mean to malign Dr. Summergrad in discussing his comments. I appreciate his candor and his commitment to education. He is both a Department Chairman [Tufts] and the President of the American Psychiatric Association, and he&#8217;s speaking from experience about a problem that is fundamental and has to be addressed &#8211; financing the academic psychiatry programs that teach medical students and residents in psychiatry. It was a front-burner problem in the 1970s when I was a part of it and experienced it first hand. And it&#8217;s apparently a big problem now. In the interim, it appears that the income from industry flowing in by various routes has kept the wolf away from the door. Unlike the way things work in most academic settings, in the clinical part of medical education, almost no one gets paid just to teach &#8211; no ivory tower. Except for a few administrators, the full-time faculty have clinical jobs [<em>and also teach<\/em>]. There are also huge volunteer physician faculties who teach for no pay except an academic credential [clinical faculty], a parking sticker, a library card, and maybe free access to the school gym. But there are still plenty of expenses, and the residents have to be paid. Grants may fund research but they don&#8217;t fund the necessary infrastructure.<\/p>\n<div align=\"justify\" class=\"small\">I wish I could say something positive to industry for their generous support of medical education. Unfortunately, such lofty motives don&#8217;t come close to describing how all of this went down. It would be more accurate to say that <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> bought themselves a tract of academic psychiatry real estate, and parlayed it into an extremely profitable investment by hook or crook. Rather than lament <em><strong><font color=\"#366c81\">PHARMA<\/font><\/strong><\/em> moving on, we would do better to celebrate the exodus and lock the door behind them &#8211; even though it leaves organized and academic psychiatry with a huge, currently unsolved problem. Perhaps we can find a less destructive solution this time around&#8230;<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Protecting Academic Psychiatry PsychiatricNews Paul Summergrad, M.D. January 2015 [full text on-line] It was APA, along with NIMH and academic psychiatry leadership in the latter part of the last century, that helped the field to develop to its current prominence. It is incumbent upon us to focus our attention on these issues so that our [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-53363","post","type-post","status-publish","format-standard","hentry","category-opinion"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/53363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=53363"}],"version-history":[{"count":103,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/53363\/revisions"}],"predecessor-version":[{"id":53467,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/53363\/revisions\/53467"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=53363"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=53363"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=53363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}