{"id":61884,"date":"2015-12-05T09:22:25","date_gmt":"2015-12-05T14:22:25","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=61884"},"modified":"2015-12-05T10:47:08","modified_gmt":"2015-12-05T15:47:08","slug":"beyond-a-reflection","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2015\/12\/05\/beyond-a-reflection\/","title":{"rendered":"beyond a reflection&#8230;"},"content":{"rendered":"\n<p align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"520\" height=\"47\" border=\"1\" src=\"http:\/\/1boringoldman.com\/images\/occam.jpg\" \/><\/p>\n<p align=\"justify\"><sup><font color=\"#200020\"><em><a href=\"https:\/\/en.wikipedia.org\/wiki\/Occam's_razor\" target=\"_blank\">Occam&rsquo;s razor<\/a>, also known as Ockham&rsquo;s razor, and sometimes expressed in Latin as lex  parsimoniae [the law of parsimony, economy or succinctness], is a  principle that  generally recommends selecting from among competing  hypotheses the one  that makes the fewest new assumptions. The strict translation is &quot;Plurality is not to be posited without necessity.&quot;<\/em><\/font><\/sup><\/p>\n<div align=\"justify\" class=\"small\">In <a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2015\/12\/04\/a-reflection\/\">a reflection&hellip;<\/a> I was talking about screening for depression&nbsp; [waiting room screening], having encountered it as both patient and doctor at the beginning of the week of Thanksgiving. I ended by saying:<\/div>\n<blockquote>\n<div align=\"justify\">But I did decide that chasing this down would be worth the effort. It  might take a while because this has obviously worked its way into  government guidelines. So I&rsquo;m going to table it for a time when I run  out of other things to look into. In the meanwhile, I&rsquo;m going to see how  it worked its way into my clinic.<\/div>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">&#8230;thinking that with all the references that appeared when I looked into the why of things, there was a lot of reading between where I was and where I needed to be to understand why both my personal doctor and the clinic I work in were screening people for depression in the waiting room with questionnaires. So I started looking for meta-analyses and studies to figure it all out. Finding the answer to the why of this business of screening for depression had suddenly come into my life turned out to be much simpler than I thought it might be. <em><font color=\"#200020\">Occam&#8217;s Razor<\/font><\/em> proposes that the simplest explanation is usually right. And this is a prime example.<\/div>\n<p>                  <\/p>\n<div align=\"justify\" class=\"small\">It takes just a couple of representative articles to summarize essence of this story. So let&#8217;s start with Canada. Back in 2005, the <a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC543939\/pdf\/20050104s00022p33.pdf\">Canadian Task Force on Preventive Health Care<\/a> had recommended depression screening. In 2012, there was a strong review article summarizing the available information in the interim. Like the Cochrane Review in <a target=\"_blank\" href=\"http:\/\/1boringoldman.com\/index.php\/2015\/12\/04\/a-reflection\/\">a reflection&hellip;<\/a>, they concluded that the Task Force should reconsider that recommendation:<\/div>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3291670\/\">Rethinking recommendations for screening for depression in primary care<\/a><\/div>\n<div align=\"center\" class=\"small\">by Brett D. Thombs, PhD, James C. Coyne, PhD, Pim Cuijpers, PhD, Peter de Jonge, PhD, Simon Gilbody, DPhil, John P. A. Ioannidis, MD DSc, Blair T. Johnson, PhD, Scott B. Patten, MD PhD, Erick H. Turner, MD, and Roy C. Ziegelstein, MD<\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Canadian Medical Association Journal<\/font><\/strong>. 2012 184[4]:413-418.<\/div>\n<div align=\"center\" class=\"middle\">[<a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3291670\/\">full text online<\/a>]<\/div>\n<p align=\"center\"><strong><font color=\"#200020\">&#8230;<\/font><\/strong><\/p>\n<p align=\"justify\"><em><strong><font color=\"#200020\">Conclusion<\/font><\/strong><\/em>:<br \/>                   The prevalence of depression and the availability of easy-to-use screening instruments make it tempting to endorse widespread screening for the disease. However, screening in primary care is a resource-intensive endeavour, does not yet show evidence of benefit and would have unintended negative effects for some patients. Evidence from one simulation study using Canadian national data found that the overall burden of depression could be reduced by providing more consistent treatment to reduce symptoms and prevent relapse among people with recurrent disorders, but not by increasing treatment through screening.<\/p>\n<p align=\"justify\">We hope that a rigorous review of current evidence will encourage the developers of future guidelines, including members of the Canadian Task Force on Preventive Health Care, to carefully consider their stance on screening for depression. We also hope that, consistent with the 2010 guidelines of the National Institute for Health and Clinical Excellence, such developers will conclude that evidence from well-conducted, randomized, controlled trials of the benefit of screening, in excess of its likely harms and costs, is needed before it can be recommended in primary care settings. Specifically, the benefits and harms of screening should be tested in a trial in which all patients identified as having depression should have access to the same integrated care for their condition, regardless of whether they are identified through screening in the intervention group or via physician recognition and referral in a control group. It is possible that such a trial would find that screening benefits patients to a degree that would justify the cost and the harms associated with the process. Until then, however, given the lack of evidence of benefit from screening and the concerns that we have described, it is not reasonable to simply assume that depression screening is good policy.<\/p>\n<div align=\"justify\"><strong><font color=\"#200020\">Key points<\/font><\/strong><\/div>\n<ul>\n<li>\n<div align=\"justify\">Screening for depression in primary care is recommended in the United States and Canada under certain conditions, but not in the United Kingdom.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">No trials have found that patients who undergo screening have better outcomes than patients who do not when the same treatments are available to both groups.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">Existing rates of treatment, high rates of false-positive results, small treatment effects and the poor quality of routine care may explain the lack of effect seen with screening.<\/div>\n<\/li>\n<li>\n<div align=\"justify\"><strong><font color=\"#990000\">Developers of future guidelines should require evidence of benefit from randomized controlled trials of screening, in excess of harms and costs, before recommending screening.<\/font><\/strong><\/div>\n<\/li>\n<\/ul>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">And that is, in fact, exactly what the <strong><font color=\"#200020\">Canadian Task Force on Preventive Health Care<\/font><\/strong> recommended the next year:<\/div>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3680556\/pdf\/1850775.pdf\">Recommendations on screening for depression in adults<\/a><\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Canadian Task Force on Preventive Health Care<\/font><\/strong><\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Canadian Medical Association Journal.<\/font><\/strong> 2013 185[9]:775-782.<\/div>\n<div align=\"center\" class=\"middle\">[<a target=\"_blank\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3680556\/pdf\/1850775.pdf\">full text online<\/a>]<\/div>\n<p align=\"center\"><strong><font color=\"#200020\">&#8230;<\/font><\/strong><\/p>\n<p align=\"justify\"><strong><font color=\"#200020\">Conclusion<\/font><\/strong>:<br \/>                Our recommendations highlight the lack of evidence about the benefits and harms of routinely screening for depression in adults. In the absence of a demonstrated benefit of screening, and in consideration of the potential harms, we recommend not routinely screening for depression in primary care settings, either in adults at average risk or in those with characteristics that may increase their risk of depression. However, clinicians should be alert to the possibility of depression, especially in patients with characteristics that may increase their risk of depression, and should look for it when there are clinical clues, such as insomnia, low mood, anhedonia and suicidal thoughts.<\/p>\n<div align=\"justify\"><strong><font color=\"#200020\">Summary of recommendations for clinicians and policy-makers<\/font><\/strong>:<br \/>               Recommendations on screening for depression in primary care settings are provided for people 18 years of age or older who present at a primary care setting with no apparent symptoms of depression. These recommendations do not apply to people with known depression, with a history of depression or who are receiving treatment for depression.<\/div>\n<ul>\n<li>\n<div align=\"justify\">For adults at average risk of depression, we recommend <u>not<\/u> routinely screening for depression. [Weak recommendation; very-low-quality evidence]<\/div>\n<\/li>\n<li>\n<div align=\"justify\">For adults in subgroups of the population who may be at increased risk of depression, we recommend <u>not<\/u> routinely screening for depression. [Weak recommendation; very-low-quality evidence]<\/div>\n<\/li>\n<\/ul>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">Their report is accompanied by a sensible <em><font color=\"#200020\">Commentary<\/font><\/em>:<\/div>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"http:\/\/www.cmaj.ca\/content\/185\/9\/753\">Why screening for depression in primary care is impractical<\/a><\/div>\n<div align=\"center\" class=\"small\">by Roger C. Bland CM MB ChB, David L. Streiner PhD<\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Canadian Medical Association Journal<\/font><\/strong>. 2013 185[9]:753-754.<\/div>\n<div align=\"center\" class=\"middle\">[<a target=\"_blank\" href=\"http:\/\/www.cmaj.ca\/content\/185\/9\/753\">full text online<\/a>]<\/div>\n<p align=\"center\"><strong><font color=\"#200020\">&#8230;<\/font><\/strong><\/p>\n<div align=\"justify\"><strong><font color=\"#200020\">Key points<\/font><\/strong><\/div>\n<ul>\n<li>\n<div align=\"justify\">There is little evidence of sufficient quality to guide practitioners about what type of screening, if any, to use to detect depression in adults in primary care settings.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">The number of false-positive screens with current assessment tools is too high, and the follow-up required to rule them out too time-consuming, to justify routine screening for depression in primary care practices.<\/div>\n<\/li>\n<li>\n<div align=\"justify\">If false-positive screens are not ruled out. patients are at increased risk of receiving the wrong diagnosis and inappropriate treatment.<\/div>\n<\/li>\n<\/ul>\n<\/blockquote>\n<p align=\"center\"><img loading=\"lazy\" decoding=\"async\" width=\"446\" height=\"496\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/cmaj.gif\" \/><br \/>           <sup>Summary for Canada, US, UK<br \/>     table from the<em> Canadian Task Force on Preventive Health Care 2013<\/em><\/sup><\/p>\n<p align=\"justify\" class=\"small\">Screening is not recommended. In the US, it says don&#8217;t screen <u>unless<\/u> you are in a system that can offer full services to evaluate, treat, and follow-up the results. <\/p>\n<div align=\"justify\" class=\"small\"><em><strong><font color=\"#990000\">So you might be asking at this point, &quot;How this is a post to explain why 1boringoldman&#8217;s doctor and 1boringoldman&#8217;s clinic are both doing routine waiting room depression screening?&quot; But that&#8217;s because you&#8217;re not thinking about the right thing &#8211; that Occam&#8217;s Razor proposes that the simplest explanation is usually right. And the answer is pretty simple. They&#8217;re doing waiting room<\/font><\/strong><\/em><em><strong><font color=\"#990000\"><em><strong><font color=\"#990000\"> depression<\/font><\/strong><\/em> screening because they&#8217;re getting paid to do waiting room<\/font><\/strong><\/em><em><strong><font color=\"#990000\"><em><strong><font color=\"#990000\"> depression<\/font><\/strong><\/em> screening.<\/font><\/strong><\/em><\/div>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"https:\/\/www.cms.gov\/medicare-coverage-database\/details\/nca-decision-memo.aspx?NCAId=251\">Decision Memo for Screening for Depression in Adults [CAG-00425N]<\/a><\/div>\n<div align=\"center\" class=\"big\"><strong><font color=\"#200020\">Centers for Medicare &amp; Medicaid Services [CMS]<\/font><\/strong><\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Final Decision<\/font><\/strong><\/div>\n<div align=\"center\" class=\"small\">October 14, 2011<\/div>\n<div align=\"center\" class=\"middle\">[<a target=\"_blank\" href=\"https:\/\/www.cms.gov\/medicare-coverage-database\/details\/nca-decision-memo.aspx?NCAId=251\">full text on-line<\/a>]<\/div>\n<p align=\"justify\">The Centers for Medicare &amp; Medicaid Services [CMS] has determined  that the evidence is adequate to conclude that screening for depression  in adults, which is recommended with a grade of B by the U.S.  Preventive Services Task Force [USPSTF], is reasonable and necessary for  the prevention or early detection of illness or disability and is  appropriate for individuals entitled to benefits under Part A or  enrolled under Part B. <\/p>\n<div align=\"justify\"><strong><font color=\"#990000\">Therefore CMS will cover annual screening for depression for Medicare  beneficiaries in primary care settings that have staff-assisted  depression care supports in place to assure accurate diagnosis,  effective treatment and follow-up.<\/font><\/strong>  For the purposes of this decision  memorandum:<\/div>\n<ul>\n<li>\n<div align=\"justify\">A primary care setting is defined as one in which there is  provision of integrated, accessible health care services by clinicians  who are accountable for addressing a large majority of personal health  care needs, developing a sustained partnership with patients, and  practicing in the context of family and community.  Emergency  departments, inpatient hospital settings, ambulatory surgical centers,  independent diagnostic testing facilities, skilled nursing facilities,  inpatient rehabilitation facilities and hospice are not considered  primary care settings under this definition.<\/div>\n<\/li>\n<li>\n<div align=\"justify\"><strong><font color=\"#990000\">At a minimum level, staff-assisted depression care supports  consist of clinical staff [e.g., nurse, physician assistant] in the  primary care setting who can advise physician of screening results and  who can facilitate and coordinate referrals to mental health treatment.<\/font><\/strong><\/div>\n<\/li>\n<\/ul>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">Medicare [and Medicaid?] pays for waiting room screening for depression in adults once a year. The whole text is online to read. They review much of the same information in the other pieces above. They allow all sorts of screening instruments [the PHQ-9 seems the shortest]. They&#8217;ve softened the U.S.  Preventive Services Task Force [USPSTF] recommendation that you only screen if you have full services to evaluate and deal with what you find out. All they require is that an assigned somebody inform the doctor of the results and then make a referral to some mental health asset. I suppose that could mean a local mental health center [or in the case of our clinic, me]. <em><strong><font color=\"#990000\">Best I can tell, they pay $17 and change for the yearly screening<\/font><\/strong><\/em>, and in the Medicare\/Medicaid world where reimbursement is generally slim, every little bit counts. Having achieved something of a handle on the why of things, I think that&#8217;s enough for the moment and I&#8217;ll defer my editorial comments to the next post. I may not have the details totally right, but I think I&#8217;m hearing the right music. As they say, &quot;<em><font color=\"#200020\">Close enough for government work<\/font><\/em>&quot;&#8230; <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Occam&rsquo;s razor, also known as Ockham&rsquo;s razor, and sometimes expressed in Latin as lex parsimoniae [the law of parsimony, economy or succinctness], is a principle that generally recommends selecting from among competing hypotheses the one that makes the fewest new assumptions. The strict translation is &quot;Plurality is not to be posited without necessity.&quot; In a [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-61884","post","type-post","status-publish","format-standard","hentry","category-opinion"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/61884","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=61884"}],"version-history":[{"count":30,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/61884\/revisions"}],"predecessor-version":[{"id":61914,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/61884\/revisions\/61914"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=61884"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=61884"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=61884"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}