{"id":63389,"date":"2016-02-10T12:46:02","date_gmt":"2016-02-10T17:46:02","guid":{"rendered":"http:\/\/1boringoldman.com\/?p=63389"},"modified":"2016-02-10T13:14:40","modified_gmt":"2016-02-10T18:14:40","slug":"ill-advised","status":"publish","type":"post","link":"https:\/\/1boringoldman.com\/index.php\/2016\/02\/10\/ill-advised\/","title":{"rendered":"ill-advised&#8230;"},"content":{"rendered":"<br \/>\n<blockquote>\n<div align=\"center\" class=\"big\"><a href=\"http:\/\/annals.org\/article.aspx?articleid=2490528\" target=\"_blank\">Screening for Depression in Children and Adolescents:<\/a><\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">U.S. Preventive Services Task Force Recommendation Statement<\/font><\/strong><\/div>\n<div align=\"center\" class=\"small\">by Albert L. Siu, MD, MSPH, on behalf of the U.S. Preventive Services Task Force<\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Annals of Internal Medicine<\/font><\/strong>. Published online 9 February 2016<\/div>\n<div align=\"center\" class=\"middle\">[<a href=\"http:\/\/annals.org\/article.aspx?articleid=2490528\" target=\"_blank\">full text on-line<\/a>]      <\/div>\n<p>         <\/p>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Description<\/font><\/strong><\/em>: Update of the 2009 U.S. Preventive Services Task Force [USPSTF] recommendation on screening for major depressive disorder [MDD] in children and adolescents.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Methods<\/font><\/strong><\/em>: The USPSTF reviewed the evidence on the benefits and harms of screening; the accuracy of primary care&ndash;feasible screening tests; and the benefits and harms of treatment with psychotherapy, medications, and collaborative care models in patients aged 7 to 18 years.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Population<\/font><\/strong><\/em>: This recommendation applies to children and adolescents aged 18 years or younger who do not have a diagnosis of MDD.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Recommendation<\/font><\/strong><\/em>: The USPSTF recommends screening for MDD in adolescents aged 12 to 18 years. Screening should be implemented with adequate systems in place to ensure accurate diagnosis, effective treatment, and appropriate follow-up. [B recommendation] The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for MDD in children aged 11 years or younger.<\/div>\n<\/blockquote>\n<blockquote>\n<div align=\"center\" class=\"big\"><a target=\"_blank\" href=\"http:\/\/annals.org\/article.aspx?articleid=2490526\">Screening for Major Depressive Disorder in Children and Adolescents:<\/a><\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">A Systematic Review for the U.S. Preventive Services Task Force<\/font><\/strong><\/div>\n<div align=\"center\" class=\"small\">by Valerie Forman-Hoffman, PhD, MPH; Emily McClure, MSPH; Joni McKeeman, PhD; Charles T. Wood, MD; Jennifer Cook Middleton, PhD; Asheley C. Skinner, PhD; Eliana M. Perrin, MD, MPH; and Meera Viswanathan, PhD<\/div>\n<div align=\"center\" class=\"middle\"><strong><font color=\"#200020\">Annals of Internal Medicine<\/font><\/strong>. Published online 9 February 2016<\/div>\n<div align=\"center\" class=\"middle\">[<a target=\"_blank\" href=\"http:\/\/annals.org\/article.aspx?articleid=2490526\">full  text on-line<\/a>]<\/div>\n<p>    <\/p>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Background<\/font><\/strong><\/em>: Major depressive disorder [MDD] is common among children and adolescents and is associated with functional impairment and suicide.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Purpose<\/font><\/strong><\/em>: To update the 2009 U.S. Preventive Services Task Force [USPSTF] systematic review on screening for and treatment of MDD in children and adolescents in primary care settings.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Data Sources<\/font><\/strong><\/em>: Several electronic searches [May 2007 to February 2015] and searches of reference lists of published literature.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Study Selection<\/font><\/strong><\/em>: Trials and recent systematic reviews of treatment, test&ndash;retest studies of screening, and trials and large cohort studies for harms.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Data Extraction<\/font><\/strong><\/em>: Data were abstracted by 1 investigator and checked by another; 2 investigators independently assessed study quality.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Data Synthesis<\/font><\/strong><\/em>: Limited evidence from 5 studies showed that such tools as the Beck Depression Inventory and Patient Health Questionnaire for Adolescents had reasonable accuracy for identifying MDD among adolescents in primary care settings. Six trials evaluated treatment. Several individual fair- and good-quality studies of fluoxetine, combined fluoxetine and cognitive behavioral therapy, escitalopram, and collaborative care demonstrated benefits of treatment among adolescents, with no associated harms.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Limitation<\/font><\/strong><\/em>: The review included only English-language studies, narrow inclusion criteria focused only on MDD, high thresholds for quality, potential publication bias, limited data on harms, and sparse evidence on long-term outcomes of screening and treatment among children younger than 12 years.<\/div>\n<div align=\"justify\"><em><strong><font color=\"#200020\">Conclusion<\/font><\/strong><\/em>: No evidence was found of a direct link between screening children and adolescents for MDD in primary care or similar settings and depression or other health-related outcomes. Evidence showed that some screening tools are accurate and some treatments are beneficial among adolescents [but not younger children], with no evidence of associated harms.<\/div>\n<\/blockquote>\n<div align=\"justify\" class=\"small\">There was a time in the not so distant past when childhood and adolescence were simply seen as the period before adulthood &#8211; a time for physical development, learning, and training. But later views had a different take on things &#8211; childhood as a sequential unfolding of multiple inter-related developmental lines that condense in adolescence with the formation of a core identity and personality that more or less persist throughout the remaining life cycle. Childhood was no longer seen as a waiting period for little men and little women to grow up. It was <strong><font color=\"#200020\">Child Development<\/font><\/strong>, and the nuances were of central importance to educators, parents, law-makers, and mental health specialists. Many of the disturbances of childhood and adolescence were seen as developmental deviations, and the efforts of people involved were directed towards moving the patient back into the main stream of development. <\/div>\n<p align=\"justify\" class=\"small\">I came to psychiatry drawn by the psychological struggles apparent in so many of the medical patients I&#8217;d seen along the way. I just didn&#8217;t get it. And learning to view them in the context of the person&#8217;s whole biography was, in itself, worth the price of admission for me. When the DSM-III with its expanded focus on distinct disorders came along, I was neither interested nor able to go back, so I went away. I understood and even agreed with many of the criticisms of what had been before, but I couldn&#8217;t live with the baby in the bathwater problem. I see non-melancholic depression as a signal that something&#8217;s wrong that needs attending rather than just a symptom to be treated. And that&#8217;s particularly true in adolescence and young adulthood. I really don&#8217;t think there&#8217;s a unitary disease, Major Depressive Disorder [MDD], even in adulthood, but I <em><font color=\"#200020\">double-dog-really<\/font><\/em> don&#8217;t think it exists in children and adolescents &#8211; certainly not in the way these articles imply. Five years volunteering in a Child and Adolescent clinic after retirement only reinforced these views.<\/p>\n<p align=\"justify\" class=\"small\">So as important as I think it is to attend to depression in adolescents, this recommendation and the accompanying review just seem way off the mark. And to present this slide as an updated &quot;Systematic Review&quot; is ludicrous:<\/p>\n<p align=\"center\" class=\"small\"><img decoding=\"async\" width=\"460\" border=\"0\" src=\"http:\/\/1boringoldman.com\/images\/screening.png\" \/><br \/><sup>[truncated to fit]<\/sup><\/p>\n<div align=\"justify\" class=\"small\">While it&#8217;s similar to the <a href=\"https:\/\/www.google.com\/url?sa=t&#038;rct=j&#038;q=&#038;esrc=s&#038;source=web&#038;cd=3&#038;ved=0ahUKEwiJh87P5O3KAhWKWh4KHcFCB80QFggsMAI&#038;url=http%3A%2F%2Fwww.uspreventiveservicestaskforce.org%2FHome%2FGetFile%2F1%2F538%2Fchdeprrs%2Fpdf&#038;usg=AFQjCNFxk6d6_22PweHTSNlJMViCXQwr8g&#038;sig2=FB-7xEMkifZalDzmSO-uDg&#038;cad=rja\" target=\"_blank\">2009 recommendation<\/a>, it&#8217;s a missed opportunity to give this issue a thorough review. So <em><font color=\"#200020\">perhaps well-intended, but definitely ill-advised<\/font><\/em> is all I can think of to say. . <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Screening for Depression in Children and Adolescents: U.S. Preventive Services Task Force Recommendation Statement by Albert L. Siu, MD, MSPH, on behalf of the U.S. Preventive Services Task Force Annals of Internal Medicine. Published online 9 February 2016 [full text on-line] Description: Update of the 2009 U.S. Preventive Services Task Force [USPSTF] recommendation on screening [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_forum_subforum_count":0,"footnotes":""},"categories":[5],"tags":[],"class_list":["post-63389","post","type-post","status-publish","format-standard","hentry","category-opinion"],"_links":{"self":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/63389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/comments?post=63389"}],"version-history":[{"count":10,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/63389\/revisions"}],"predecessor-version":[{"id":63400,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/posts\/63389\/revisions\/63400"}],"wp:attachment":[{"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/media?parent=63389"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/categories?post=63389"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/1boringoldman.com\/index.php\/wp-json\/wp\/v2\/tags?post=63389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}