Fraud in the Scientific Literature New York Times Editorial October 5, 2012 A surprising upsurge in the number of scientific papers that have had to be retracted because they were wrong or even fraudulent has journal editors and ethicists wringing their hands. The retracted papers are a small fraction of the vast flood of research […]
Words Matter NIMH Director’s Blog By Thomas Insel October 02, 2012 Those who constructed the DSM were looking for a common language to describe symptoms, not a common biology or a common treatment. As someone who entered psychiatry pre-DSM-3, I can attest to the value of a common language. But there have been costs as […]
David Kessler’s expert report is as damaging as Rothman’s from the earlier Texas Trial. Here’s just a paragraph from an Excerpta Medica document presented to Janssen in 2003: The original article [Abstract below] doesn’t mention Tim Coffey anywhere. This list of articles are the influential articles that launched Risperdal’s wide use. Note that the Aman […]
Former FDA chief David Kessler says J&J broke the law in promoting Risperdal The Philadelphia Inquirer by David Sell October 4, 2012 Former U.S. Food and Drug Administration Commissioner David Kessler, a pediatrician by training, said that Johnson & Johnson and its Janssen subsidiary broke the law in marketing its antipsychotic drug Risperdal for use […]
Finding the actual data from Study 329 posted in early August was invigorating [a movement…]. I could finally have a go at looking at the things I’d only been able to guess about before. For example, I knew that the authors of that Study had abandoned a primary outcome parameter [HAM-D either ≤50% baseline or […]
Misconduct accounts for the majority of retracted scientific publications by Ferric C. Fang, R. Grant Steen, and Arturo Casadevall Proceedings of the National Academy of Sciences. 2012 Oct 1. [Epub ahead of print] A detailed review of all 2,047 biomedical and life-science research articles indexed by PubMed as retracted on May 3, 2012 revealed that […]
[reference] As many times as I’ve read about ghost-writing, I still find it jarring. This is the format of the Rothman Report, the questions Dr. Rothman was asked with his answer followed by the examples from the subpoenaed documents that lead him to his conclusions" [reference] [reference] I could go on and on cutting out […]
Jury Hears From Teen Boy’s Doc At Risperdal Trial Law360 By Matt Fair September 28, 2012 In a video deposition shown to jurors Friday, the doctor of a teenager claiming he grew breasts after taking the antipsychotic drug Risperdal said that the boy suffered from severe developmental and behavioral problems, and that he was unaware […]
While Freud’s advice about the dangers of therapeutic zeal was directed at overly ambitious psychotherapists, it might’ve been decent advice for the modern NIMH and academic research community. Though an outsider in the world of neuroscience, it seemed to me that there was a glaring paradox in the time-frame when psychiatry actually became so much […]
BIAS ALERT: I am constitutionally biased against Clinical Research Organizations and the ACRO as they currently exist. I don’t trust recruited patient data. I’m suspicious of the big push for globalization. And I think their association with medical writing firms and advertising is beyond suspicious. I’m sure that my reaction has to do with some […]