A ghost-writer is a hired writer who takes the data and creates the structure and arguments that will ultimately become the submitted paper – in other words, the author of the first draft. 1boringoldman Is that definition enough to cover what has us all in such an uproar? Maybe not. It does define a ghost-writer […]
Back around the century change, the NIMH funded a number of large clinical trials. While most were more credible than some of the industry offerings, C.A.T.I.E. stood out to me as the solid citizen in the lot. The outcome parameter was genuinely digital, continuation or discontinuation of the medication. The P.I. was Jeffrey Lieberman [next […]
"The medical community is currently trying to come to grips with the idea that much of the clinical trial literature has not been written by named authors, and, instead, has been written by medical writers employed by pharmaceutical companies who are not listed on the author byline. The success of virtually all of the blockbuster […]
As drug industry’s influence over research grows, so does the potential for bias Washington Post By Peter Whoriskey November 24, 2012 The article is long and well done. It tells the story of Avandia and of Cleveland Clinic cardiologist Steven Nissen’s persistence in bringing its toxicity to light. Then there are the usual suspects, Vioxx […]
This is going to be a long post because I couldn’t figure how to parse it into chunks. It’s about Paxil Study 352 mentioned before [go pogo…, closer to becoming indelible…, and recently back on the front burner…]. This first quote is the Study write-up dated 2004 and is as close to the protocol as […]
If we want things to stay as they are, things will have to change. Prince Don Fabrizio Salina in Lampedusa’s The Leopard Why all pharmaceutical research should be made open access The government wants to make all publicly funded research available – but the same must be demanded of pharmas also guardian.co.uk by Cory Doctorow […]
The first time I heard the term Scandal Fatigue, I thought, "Those journalists. They can really come up with some nonsense." If any of them heard my thoughts, I apologize. It’s probably a better diagnosis than some that made it into the DSM-5. It’s a dangerous mental illness, because it dampens the outrage that is […]
"Giovanni Fava has written perceptively about self-interested power elites within academic psychiatry…" Bernard Carroll Dr. Carroll’s comments are always welcomed, but his response to the last post contains a reference to an article by Dr. Giovanni Fava that puts words to a music I haven’t heard in a while. Here’s the abstract, but the full […]