Toward a New Era of Trust and Transparency in Clinical Trials JAMA by Kathy L. Hudson, PhD; Michael S. Lauer, MD; and Francis S. Collins, MD, PhD September 16, 2016. Trial Reporting in ClinicalTrials.gov — The Final Rule New England Journal of Medicine by Deborah A. Zarin, M.D., Tony Tse, Ph.D., Rebecca J. Williams, Pharm.D., […]
Today is an anniversary for me. This post from a year ago today … study 329 vi – revisited… Posted on Wednesday 16 September 2015 Well, our RIAT article, Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence, is finally published online at the British Medical Journal. […]
New Study Finds Therapy, Antidepressants Equally Effective At Monetizing Depression NEWS IN BRIEF The Onion. 2015 51[7]:1-2. Noting that similar outcomes were achieved under both approaches, a landmark decade-long study of mental health treatment options published Tuesday has found that talk therapy and antidepressant medications are equally effective at monetizing clinical depression. “Our data indicate […]
I first heard the term ghost-writing used in the scientific literature at the end of 2010 [see roaches…]. I must’ve known what was coming because I added added the roach to the ad image [from something our exterminator said, "For every roach you see, there are a hundred behind the walls"]. Sure enough, six months […]
So what… Miles Davis
I was once a Primary Care Physician of sorts, an internist seeing referrals from general medical officers in a military hospital so I saw a lot of people whose physical complaints reduced down to matters psychological. I think it’s very different now, but thise the latter days of the Viet Nam War, and there was […]
Unless you’re a race car driver with a manual transmission, you don’t notice the dashboard gauge on the far right. You just glance at the speedometer on the left that tells you how fast you’re going [mph]. The tachometer on the right tells you how fast the motor’s turning [rpm]. It lets the speed demon […]
No matter how comprehensive the back-up system for your computer, when lightning strikes, things get lost. After I got my new machine Wednesday afternoon, I commenced reconstituting things – reinstalling software, restoring backed-up documents, email files, graphics, etc. By last night I was pleased with my progress [though cringing at the thought of going through […]
Nosing around about Ketamine, I ran across this draft that I never posted from 2½ years ago: from February 19, 2014: Neuroskeptic has an interesting thing going trying to figure out if the effect on depressed people from Ketamine is because Ketamine is a pharmacologic antidepressant, or, to put it in my own worlds, does […]
If you’re too young to remember what this photo is, it means I’m back…