medicine at its worst…

Posted on Monday 8 August 2011


More Antidepressants Are Given Without Diagnosis
Pharmalot
by Ed Silverman
August 5th, 2011

Should a patient first be diagnosed with a psychiatric problem before receiving a prescription? Well, nearly 73 percent of antidepressants prescribed in the US in 2007 were generated without a psychiatric diagnosis, up from nearly 60 percent in 1996. And the percentage of antidepressants prescribed to patients without a diagnosis more than doubled to 6.4 percent from 2.5 percent of all visits to docs who were not psychiatrists, according to a study in Health Affairs.

To be more specific, among primary care providers, antidepressant prescriptions rose from 3.1 percent during that period to 7.1 percent. And among other docs who are not psychiatrists, visits without a psychiatric diagnosis grew from 1.9 percent to 5.8 percent. Meanwhile, antidepressants prescribed with a psychiatric diagnosis increased to 2.4 percent from 1.7 percent…

Although the researchers acknowledge the results do not specifically indicate a rise in inappropriate use of antidepressants, they argue the findings suggest that antidepressants are being prescribed for uses not supported by clinical evidence. They noted that patients who were prescribed the pills by docs other than psychiatrists and not diagnosed with a psychiatric disorder tended to suffer from diabetes, heart disease, or multiple medical conditions; have excessive fatigue and headaches; and to complain of nonspecific pain or abnormal sensations…
Here’s the referenced abstract…
Proportion Of Antidepressants Prescribed Without A Psychiatric Diagnosis Is Growing
by Ramin Mojtabai and Mark Olfson
Health Affairs [2011] 30:1434-1442.

Over the past two decades, the use of antidepressant medications has grown to the point that they are now the third most commonly prescribed class of medications in the United States. Much of this growth has been driven by a substantial increase in antidepressant prescriptions by nonpsychiatrist providers without an accompanying psychiatric diagnosis. Our analysis found that between 1996 and 2007, the proportion of visits at which antidepressants were prescribed but no psychiatric diagnoses were noted increased from 59.5 percent to 72.7 percent. These results do not clearly indicate a rise in inappropriate antidepressant use, but they highlight the need to gain a deeper understanding of the factors driving this national trend and to develop effective policy responses. To the extent that antidepressants are being prescribed for uses not supported by clinical evidence, there may be a need to improve providers’ prescribing practices, revamp drug formularies, or vigorously pursue implementation of broad reforms of the health care system that will increase communication between primary care providers and mental health specialists.
Here lies the essence of the issue raised by Drs. Mojtabai and Olfson – they propose that we "vigorously pursue implementation of broad reforms of the health care system that will increase communication between primary care providers and mental health specialists," thinking that this rise in the inappropriate prescription of antidepressants might be curbed if the primary care physicians would communicate more with psychiatrists. That’s completely wrong, totally backwards. This rise in the inappropriate prescription of antidepressants is because of the communication between primary care providers and mental health specialists – specifically psychiatrists [kols] on pharmaceutical speaker’s bureaus who travel the country touting the wonders of the antidepressants, implicitly [and explicitly] encouraging their use [aided by patient requests from the television ads that end, "Ask your doctor if antidepressant x is right for you"].

That’s the whole point of this and many other blogs that endlessly document the fact that the pharmaceutical companies have paid many millions of dollars to psychiatrists to actively teach primary care physicians to give their patients antidepressants. In my last post, I mentioned a ghostwritten editorial "authored" by several prominant psychiatrists saying:
    The weight of evidence is so persuasive that there should never again be a valid reason for not aggressively seeking out and treating depression in medically ill patients. Increasing awareness, reducing stigma, and maintaining a high level of vigilance for depression in medically ill patients must become a priority for clinicians.
I called the psychiatrists behind this collusion with the pharmaceutical companies a fraternity of pseudoscientists… – a harsh indictment – but it is an indictment much easier to prove than the effectiveness of antidepressants in medically ill people. The findings above are the result of an irresponsible campaign by drug manufacturers aided by way too many psychiatrists that has resulted in massive corporate profits, but has been of questionable benefit for patients or, in fact, the legitimacy of the psychiatric profession.

The great irony is that the antidepressants in question are now mostly out of patent, so we are left with the wreckage of this campaign and these same forces at work to add other drugs to treat "treatment resistant depression" in the patients who predictably didn’t respond as advertised in the first round. This is medicine at its worst…

Update: Oh look! They’re reporting the same phenomenon with the Atypical Antipsychotics. My comment: "Ditto!". Hat Tip to Soulful Sepulcher!
National Trends in the Antipsychotic Treatment of Psychiatric Outpatients With Anxiety Disorders
by Comer JS, Mojtabai R, and Olfson M.
American Journal of Psychiatry 2011 Jul 28. [Epub ahead of print]

Objective: The purpose of the present study was to examine patterns and recent trends in the antipsychotic medication treatment of anxiety disorders among visits to office-based psychiatrists in the United States.
Method: Annual data from the 1996-2007 National Ambulatory Medical Care Survey were analyzed to examine the patterns and trends in antipsychotic medication treatment within a nationally representative sample of 4,166 visits to office-based psychiatrists in which an anxiety disorder was diagnosed.
Results: Across the 12-year period, antipsychotic prescriptions in visits for anxiety disorders increased from 10.6% (1996-1999) to 21.3% (2004-2007). Over the study period, the largest increase in antipsychotic prescribing occurred among new patient visits. Antipsychotic prescribing also significantly increased among privately insured visits and visits in which neither antidepressants nor sedative/hypnotics were prescribed. Among the common anxiety disorder diagnoses, the largest increase in antipsychotic medication treatment was observed in visits for panic disorder. Antipsychotic prescribing rose from 6.9% (1996-1999) to 14.5% (2004-2007) among visits for anxiety disorders in which there were no co-occurring diagnoses with an indication approved by the Food and Drug Administration for antipsychotic medications.
Conclusions: Although little is known about their effectiveness for anxiety disorders, antipsychotic medications are becoming increasingly prescribed to psychiatric outpatients with these disorders.
  1.  
    SG
    August 8, 2011 | 2:28 PM
     

    You know, I can’t resist. Allow me this indulgence. The Onion, America’s best satire newspaper, just published an article entitled, “Pfizer launches ‘Zoloft for Everything’ Ad Campaign.” What’s most frightening about this (fake) article is how eerily accurate it is, considering what we know about psych med prescriptions. You know this country’s flushed when reality mirrors a fake news article!

    LINK: http://www.theonion.com/articles/pfizer-launches-zoloft-for-everything-ad-campaign,297/

  2.  
    Peggi
    August 9, 2011 | 7:11 AM
     

    Thank you, SG. I don’t usually start my days laughing but sure did today because of this Onion article.

  3.  
    August 10, 2011 | 12:52 AM
     

    America has a problem if so many ppl need antipsychotics! such an enormous, dangerous side effect profile for anxiety meds!

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